Zhang R, Wang H, Tian Y-Y, Yu X, Hu T, Dummer PMH. Use of cone-beam computed tomography to evaluate root and canal morphology mandibular molars in Chinese individuals. International Endodontic Journal, 44, 990–999, 2011. Aim To the configuration permanent first second molar teeth a subpopulation using (CBCT). Methodology Patients who required CBCT radiographic examinations as part their routine examination, diagnosis treatment planning, were enrolled. Cases where anatomy was compromised by...

To investigate variations in root canal configuration the maxillary permanent molar teeth of a Chinese subpopulation using cone-beam computed tomography (CBCT).A total 269 patients with healthy, untreated, well-developed molars were enrolled, including those suffering facial trauma, and who required pre-operative assessment for implants. Radiographic examination by CBCT was conducted as part their routine examination, diagnosis treatment planning. Overall, 299 first 210 second examined vivo...

To evaluate the external and internal anatomy of maxillary first premolar teeth in a Chinese subpopulation using cone-beam computed tomography (CBCT).A total 300 CBCT images involving were obtained from 241 patients who underwent scanning as part an oral dental examination for bone mass before placement implants or to locate impacted orthodontic therapy. Tooth position, number roots, canal configuration, canals apical foramina per root investigated. The Fisher's exact test was used analyse...

Curcumin exhibits anti-inflammatory effects and has been suggested as a treatment for inflammatory diseases. The aim of this study was to investigate the curcumin on lipopolysaccharide induced response in rat gingival fibroblasts vitro ligation-induced experimental periodontitis vivo, speculate possible mechanism curcumin. were incubated with different concentrations absence or presence (LPS). Concentrations interleukin-1β(IL-1β), tumor necrosis factor-α (TNF-α), osteoprotegerin (OPG)...

Both substance P and hypoxia-inducible factor 1 alpha (HIF-1α) are involved in inflammation angiogenesis. However, the relationship between HIF-1α rat periodontitis is still unknown.Ligation-induced was established to observe distribution expression of by immunohistochemistry. Rat gingival fibroblasts were cultured stimulated with Porphyromonas gingivalis lipopolysaccharide (LPS). Recombinant applied elaborate vitro. Primary mouse bone marrow-derived macrophages (BMMs) isolated effect on...

Multiple idiopathic external cervical root resorption is a rare condition with numerous predisposing factors that have not yet been clearly elucidated. In addition, its diagnosis and treatment pose challenges for clinicians, thus, the extraction of involved teeth commonly performed. Here, we report 29-year-old pregnant woman no contributory medical or family/social history who experienced progressed aggressively all permanent teeth. This case unique owing to involvement Reports multiple are...

Abstract Background The mandibular second molars demonstrate variations on root and canal morphology. aim of this study was to investigate all the morphology analyze morphological in patients by gender age a Chinese population use CBCT imaging. Methods Cone-beam computed tomographic images 1200 bilateral were obtained from 600 (300 females 300 males) who required preoperative assessment for implant surgery, surgical removal impacted teeth, orthodontic treatment, surgery maxillofacial tumour...

Background Nerve and its related factors in the occurrence development of periodontitis are worthy further study. Denervation research is a useful addition to nerve innervation studies. The aim this study establish rat model inferior alveolar transection combined with ligature‐induced elucidate effects denervation on periodontitis. Material Methods Sixty‐four Wistar rats were distributed four groups randomly: ligation (L); (D); ligation+denervation ( LD ); normal (N) as control. A...

Background and Objective Periodontal ligament‐associated protein‐1 ( PLAP ‐1) is an important regulator of osteogenic differentiation periodontal ligament cells plays role in the homeostasis tissues. But ‐1 periodontitis poorly understood. Expressions experimental are observed to elucidate whether gets involved pathogenesis periodontitis. Material Methods Wistar rats were randomly allocated two groups (n = 6/group): Ligation group Control group. expression was assessed by...

Characterizations of rat mandibular second molar extraction socket with significantly different buccal and lingual alveolar ridge width remain unclear.To observe alterations in the after molars, to examine processes healing an experimental model absorption preservation.Eighteen Wistar rats were included divided into six groups regarding time study. Bilateral molars extracted. The tooth sockets took 0, 1.5, 2, 3, 4 8 weeks healing. Histological observation, tartrate-resistant acidic...

Abstract It has been known that periodontal ligament‐associated protein‐1 (PLAP‐1/Asporin) not only inhibits cartilage formation in osteoarthritis, but it also influences the healing of skull defect. However, effect and mechanism PLAP‐1/Asporin on mutual regulation osteoclasts osteoblasts periodontitis are clear. In this study, we utilized a gene knockout (KO) mouse model to research unknown issue. We cultured bone marrow mesenchymal stem cells with Porphyromonas gingivalis...

The aim of the present study was to assess roles periodontal ligament‑associated protein‑1 (PLAP‑1) in osteogenic differentiation rat bone marrow stromal cells (rBMSCs) and osteoclast activation during repair defects. Male, 6‑week‑old, Wistar rats treated with defects were randomly assigned 3 groups: PLAP‑1‑transfected rBMSC group (PLAP‑1 group), empty vector‑transfected (vector group) normal (control group). Specimens obtained at 2, 4 6 weeks post‑surgery. Histological observation...

Neural stem cells (NSCs) are multipotent that generating various neural cells, including neurons, astrocytes and oligodendrocytes. This showed NSCs is an ideal candidate in the application of disease treatment. In current study, we established a simple efficient method to promote viability induce differentiation by stimulating with magnesium.The proliferation was determined MTT assay immunostaining. The behavior alteration measured rotorod test Morris water maze.Magnesium enhanced NSCs....

The study is to verify whether Calcitonin gene related peptide (CGRP) gene-modified rat bone mesenchymal stem cells (BMSCs) are promising seed with great potential repair defect. A recombinant lentiviral vector overexpressing CGRP peptide, pLenO-DCE-CGRP, was constructed and transfected into rBMSCs obtain stable expression. Differently rBMSCs: CGRP- modified (CGRP group), empty vector- (Vector group) normal (Control were transferred collagen scaffold skull defects (n=6). Skull specimens...