A5100741041- Epilepsy research and treatment
- Particle physics theoretical and experimental studies
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Plant Disease Management Techniques
- Metabolism and Genetic Disorders
- Nematode management and characterization studies
- Parkinson's Disease Mechanisms and Treatments
- Particle Detector Development and Performance
- Neurogenesis and neuroplasticity mechanisms
- Neurological disorders and treatments
- Autoimmune Neurological Disorders and Treatments
- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Fungal Biology and Applications
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Plant Disease Resistance and Genetics
- Plant Virus Research Studies
- Vector-borne infectious diseases
- Cytomegalovirus and herpesvirus research
- Infectious Encephalopathies and Encephalitis
China Meteorological Administration
2024
Chongqing Academy of Agricultural Sciences
2018-2023
Nanjing Medical University
2008-2022
Nanjing Brain Hospital
2009-2022
Chinese Academy of Agricultural Sciences
2010-2019
Affiliated Hospital of North Sichuan Medical College
2019
Shanghai Veterinary Research Institute
2019
Leibniz Institute for Jewish History and Culture – Simon Dubnow
2014
Institute of Physics, Academia Sinica
2010-2011
Institute of Vegetables and Flowers
2010
Uncertainty exists over the size of potential beneficial effects medical treatments targeting hematoma growth in intracerebral hemorrhage (ICH). We report associations parameters on clinical outcomes pilot phase, Intensive Blood Pressure Reduction Acute Cerebral Hemorrhage Trial (INTERACT1) (ClinicalTrials.gov NCT00226096).In randomized patients with both baseline and 24-hour brain CT (n = 335), between measures absolute relative 90-day poor death dependency (modified Rankin Scale score 3-5)...
Herein, the fermentation and digestion behavior of Volvariella volvacea polysaccharide (VVP) were examined through in vitro simulation experiment. The results revealed that succeeding simulated salivary gastrointestinal digestion, molecular weight VVP was reduced by only 8.9 %. In addition, reducing sugar, uronic acid, monosaccharide composition Fourier transform infrared spectroscopy characteristics did not change significantly, which indicate saliva-gastrointestinal could digest VVP....
Background Little is known regarding the role of microbiome paranasal sinuses and its contribution to sinus mucosal health disease. Consequently, we examined chronic rhinosinusitis patients with polyps (CRSwNP) a control population provide new insights into microbiota associated pathogenesis CRSwNP. Methods Fifty‐nine CRSwNP 27 controls were enrolled in study. The bacterial communities middle meatus detected using 16S ribosomal RNA (rRNA)‒targeted Illumina MiSeq sequencing after microbial...
China produces the largest amount of spent mushroom substrate (SMS) in production industry. The SMS are residual compost waste that can lead to environmental pollution. Recycling as fertilizer is a growing opportunity for agriculture, but its efficiency relatively low. In this study, we introduced novel application strategy industry turn conventional into renewable biochar SMS. A cultivation experiment with oyster (Pleurotus ostreatus) was conducted evaluate benefits producing edible...
Background and Purpose— We aimed to develop a risk score (intracerebral hemorrhage–associated pneumonia score, ICH-APS) for predicting hospital-acquired stroke-associated (SAP) after ICH. Methods— The ICH-APS was developed based on the China National Stroke Registry (CNSR), in which eligible patients were randomly divided into derivation (60%) validation (40%) cohorts. Variables routinely collected at presentation used SAP For testing added value of hematoma volume measure, we separately 2...
Although studies have explored some dietary patterns for Parkinson's disease (PD), more other and food item under the pattern are needed to investigate. This study aimed identify categories of PD further explore association single with PD.The 2015-2018 US National Health Nutritional Examination Survey (NHANES) database was used data extraction. The on demographics nutrient intake were collected. Dietary derived from by factor analysis. between or using logistic regression analysis in overall...
Potassium is a nutrient element necessary for tobacco growth. Tobacco leaves with high potassium content are elastic and tough, rich in oil. And the same time, can also improve scent aromatic value of flue-cured by regulating synthesis hydrocarbons leaves.. It an important quality indicator tobacco. However, concentration most areas China generally lower than global standard Two genotypes were grafted to each other under different levels test whether plant growth be improved grafting The all...
The low Potassium (K) content in flue-cured tobacco leaves severely restricts the development of China's high-quality cigarette industry. To determine whether quality can be improved by grafting, a cross-grafting experiment two different K-efficiency strain (Yunyan 87, main cultivar. WuFeng No.2, K-efficient genotype) was carried out. Measurement data from field with three K supply levels (0,135 and 270 kg K2O ha−1) four grafting combinations ['Wufeng No. 2'(W), 'Yunyan 87'(Y), Y/W (Y...
To evaluate the non-inferiority of pramipexole extended-release (ER) versus immediate-release (IR) in Chinese patients with Parkinson's disease (PD) a double-blind, randomized, parallel-group study.Subjects were idiopathic PD diagnosis ≥ 2 years prior to trial, age 30 old at diagnosis, and Modified Hoehn Yahr score 2-4 during 'on'-time. Subjects received treatment ER (n=234) or IR (n=239). Non-inferiority was based on primary endpoint, change from baseline end maintenance (week 18) UPDRS...
Indirubin-3′-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play obligate role in neuronal apoptosis Alzheimer's disease. Here, we found that indirubin-3′-monoxime improved the morphology increased survival rate SH-SY5Y cells exposed to amyloid-beta 25–35 (Aβ25–35), also suppressed by reducing tau phosphorylation at Ser199 Thr205. Furthermore, inhibited glycogen synthase kinase-3β (GSK-3β). Our results suggest reduced Aβ25–35-induced suppressing...
Laboratory and field culture experiments have been carried out at two sites which show that temperature soil moisture significantly affected nitrogen mineralization in the a tobacco field. Intermittent leaching under aerobic incubation conditions was adopted to develop dynamic simulation models of organic different regimes (10, 15, 20, 25, 30, 35, 20 °C) gravimetric content (0.1, 7%, 13%, 20%, 27%, 33%, 40%, 47%, 53%). The results highest N rate appeared 35°C lowest 10°C. Soil rate, as by...
This paper reported an unusual manifestation of a 19-year-old Chinese male patient presented with complex phenotype mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome Kearns–Sayre (KSS). He was admitted to our hospital the chief complaint "acute fever, headache slow reaction for 21 days". initially misdiagnosed as "viral encephalitis". man significant past medical history intolerating fatigue paroxysmal neurobehavioral attacks that started about 10...
Rhipicephalus haemaphysaloides is a widespread tick species in China and other South East Asian countries, where it the vector of many pathogens. The objective this study was to role serpin (serine protease inhibitor) during tick-host interaction. differentiation bone marrow-derived dendritic cells (BMDC) induced vitro, effect RHS2 on maturation DCs evaluated. effects T cell activation cytotoxic lymphocytes' (CTLs) activity were analyzed by flow cytometry. Antibody subtypes after...
In the previous study, we investigated alleviation effect of grafting on potassium uptake in roots and tobacco growth inhibition under low stress. However, stress perception coping mechanism at whole plant level is not clear now. order to clearly understand impact deficit responding tobacco, a mutual experiment has been conducted two varieties ('Wufeng No.2' 'Yunyan 87') different K supply (5 mmol L- 1 0.5 K).The results show that compared with self-rooted seedlings, significantly increased...
Background: Pramipexole (PPX), a non-ergot dopamine receptor agonist, is first-line treatment for Parkinson’s disease (PD). A critical dose level above which better benefit-to-harm ratio exists has not been examined. Methods: Chinese PD patients (n=464) were retrospectively analyzed by PPX maintenance dose, stage, combined levodopa and baseline tremor contribution. The sum score of Baseline Activities Daily Living (part II) Motor Examination (III) the Unified Disease Rating Scale (UPDRS...
Recent reports suggest that bone marrow stromal cells may be induced into neural both in vivo and vitro. The factors regulate the differentiation mechanism involved, however, remains unclear. Here we demonstrated granulocyte-macrophage colony-stimulating factor (GM-CSF), a potent hematopoietic factor, was able to enhance of cells. Moreover, found GM-CSF receptors are abundantly distributed significantly upregulated phosphorylation cAMP-responsive element binding protein These findings...
This study is aimed at investigating the lymphocyte subsets of cerebrospinal fluid (CSF) to provide possible differential diagnostic values and better understand pathophysiological mechanism underlying autoimmune encephalitis (AE) infectious lymphocytic encephalitis. A series CD markers, including CD3/4/8/20 representing different types developmental stages lymphocytes, were used count corresponding subpopulations CSF from clinical laboratory confirmed cases anti-N-methyl-D-aspartate...
Potassium deficiency is a major problem limiting tobacco ( Nicotiana tabacum ) growth, and grafting has the potential to alleviate it. To compare photosynthetic performance of grafted under different potassium levels, Yunyan 87 (main cultivar) Wufeng No. 2 (potassium high-efficiency were selected conduct mutual trials in form hydroculture with two supply levels (5 mmol·L −1 K 0.5 K). The plant gas exchange parameters, chlorophyll fluorescence, initial ribulose-1,5-bisphosphate...
A dynamical valence and sea quark mixing model is shown to fit the baryon ground state properties as well spin content of nucleon. The relativistic correction ${q}^{3}\ensuremath{\leftrightarrow}{q}^{3}q\overline{q}$ transition terms induced by axial vector current $\overline{\ensuremath{\psi}}\stackrel{\ensuremath{\rightarrow}}{\ensuremath{\gamma}}{\ensuremath{\gamma}}^{5}\ensuremath{\psi}$ in this space responsible for reduction.
This study was to investigate the differences of lymphocyte in cerebrospinal fluid ( CSF ) patients with syphilis meningitis SM and tuberculous TBM for new diagnostic insights. Totally, 79 cases 45 were enrolled. In , CD 4, RO or 20 positive lymphocytes detected by immunohistochemistry. The proportion 4 T cells significantly higher than that (p < 0.05). After medical therapy, there a decline trend T‐cell both groups less ratio increased group 20B not obviously different between two during...
Adult, male, Sprague-Dawley rats were injected with granulocyte-macrophage colony-stimulating factor-transfected bone marrow stromal cells (GM-CSF-BMSCs) into the ischemic boundary zone at 24 hours after onset of middle cerebral artery occlusion. Results showed reduced infarct volume, decreased number apoptotic cells, improved neurological functions, increased angiogenic factor expression, and vascular density in that underwent GM-CSF-BMSCs transplantation compared BMSCs group. Experimental...