A5012927531- Nutrition and Health in Aging
- Head and Neck Cancer Studies
- Attention Deficit Hyperactivity Disorder
- Oral health in cancer treatment
- Cancer Diagnosis and Treatment
- Frailty in Older Adults
- Childhood Cancer Survivors' Quality of Life
- Dysphagia Assessment and Management
- Clinical Nutrition and Gastroenterology
- Nutritional Studies and Diet
- Genetics and Neurodevelopmental Disorders
- Functional Brain Connectivity Studies
- Cancer Immunotherapy and Biomarkers
- Genetic Associations and Epidemiology
- Health, Environment, Cognitive Aging
- Cancer Risks and Factors
- Diet and metabolism studies
- Health and Lifestyle Studies
- Cancer, Lipids, and Metabolism
- Body Composition Measurement Techniques
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Epigenetics and DNA Methylation
- Substance Abuse Treatment and Outcomes
- Skin Protection and Aging
Institut Català d'Oncologia
2016-2025
Vall d'Hebron Institut de Recerca
2019-2024
Universitat Autònoma de Barcelona
2019-2024
Institut d'Investigació Biomédica de Bellvitge
2013-2024
Universitat de Barcelona
2017-2024
Institut Català d'Ornitologia
2018-2024
Vall d'Hebron Hospital Universitari
2019-2023
Bellvitge University Hospital
2017-2022
Duran i Reynals Hospital
2012-2020
Ajuntament de L’Hospitalet
2018
Compelling evidence supports alterations in gut microbial diversity, bacterial composition, and/or relative abundance of several taxa attention-deficit/hyperactivity disorder (ADHD). However, findings for ADHD are inconsistent among studies, and specific microbiome signatures the remain unknown. Given that previous studies have mainly focused on pediatric form involved small sample sizes, we conducted largest study to date compare gastrointestinal composition 100 medication-naïve adults with...
Substance use disorder (SUD) often co-occur at high prevalence with other psychiatric conditions. Among them, attention-deficit and hyperactivity (ADHD) is present in almost one out of every four subjects SUD associated higher severity, more frequent polysubstance dependence increased risk for mental health problems patients. Despite studies suggesting a genetic basis the co-occurrence these two conditions, factors involved joint development both disorders mechanisms mediating causal...
Patient Generated Subjective Global Assessment (PG-SGA) is a validated tool for nutrition evaluation in patients with cancer.The aim of our study was to estimate the prevalence malnutrition head and neck cancer at diagnosis evaluate independent prognostic factors from PG-SGA.All outpatients attending Head Neck Cancer Multidisciplinary Meeting primary diagnosis, staging treatment were evaluated by an oncology dietitian using patient generated subjective global assessment (PG-SGA). Patients...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental that often persists into adulthood. There growing evidence epigenetic dysregulation participates in ADHD. Given only limited number of epigenome-wide association studies (EWASs) ADHD have been conducted so far and they mainly focused on pediatric population-based samples, we performed an EWAS clinical sample adults with We report one CpG site four regions differentially methylated between...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental that results from the interaction of both genetic and environmental risk factors. Genome-wide association studies have started to identify multiple loci associated with ADHD, however, exact causal genes biological mechanisms remain largely unknown. We performed multi-step analysis characterize modules co-expressed ADHD using data peripheral blood mononuclear cells 270 cases 279 controls....
Abstract Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are strongly associated with educational attainment (EA), but little is known about their genetic relationship school performance whether these links explained, in part, by the liability of EA. Here, we aim to dissect polygenic contribution ADHD ASD performance, early manifestation psychopathology other psychiatric related traits To do so, tested association scores for EA, assessed influenced...
Abstract Substance use disorder (SUD) is a global health problem with significant impact on individuals and society. The presentation of SUD diverse, involving various substances, ages at onset, comorbid conditions, disease trajectories. Current treatments for struggle to address this heterogeneity, resulting in high relapse rates. often co-occurs other psychiatric mental health-related conditions that contribute the heterogeneity predispose adverse Family genetic studies highlight role...
Background Reduced muscle mass has been associated with increased treatment complications in several tumor types. We evaluated the impact of skeletal index (SMI) on prognosis and immune-related adverse events (IrAEs) a cohort recurrent/metastatic (R/M) head neck squamous cell carcinoma (HNSCC) treated immune checkpoints inhibitors (ICI). Methods A single-institutional, retrospective study was performed including 61 consecutive patients R/M HNSCC diagnosed between July 2015 December 2018. SMI...
Abstract Background The influence of nutrition on breast cancer prognosis is still inconclusive and therefore dietary interventions incorporating biomarkers are needed to confirm compliance with goals clarify biological mechanisms. present study assessed whether a lifestyle intervention in survivors could affect fruit vegetables fatty acids. Methods In this phase II single‐arm trial, 37 overweight/obese early stage patients completed 12‐week diet exercise intervention. involved 1‐h weekly...
Induction chemotherapy (ICT) followed by definitive treatment is an accepted non-surgical approach for locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC). However, ICT remains a challenge cisplatin-unfit patients. We evaluated paclitaxel cetuximab (P-C) as in cohort of LA-HNSCC patients unfit cisplatin.This retrospective analysis with newly diagnosed considered cisplatin-based (age >70 and/or ECOG≥2 comorbidities) treated weekly P-C radiotherapy (RT-C) between 2010...
This study assessed changes in quality of life (QoL) and cardiorespiratory fitness (CRF) during a diet physical activity (PA) intervention breast cancer (BC) survivors investigated the relation between these changes. The this single-arm pre-post involved supervised, 1-hour weekly, sessions 75-minute bi-weekly PA moderate-to-high intensity. 12-week targeted overweight/obese women who had recently completed BC treatment. Pre- post-CRF QoL measurements were compared using paired t-tests. Linear...
Abstract Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental characterized by age-inappropriate symptoms of inattention, impulsivity and hyperactivity that persist into adulthood in the majority diagnosed children. Despite several risk factors during childhood predicting persistence ADHD adulthood, genetic architecture underlying trajectory over time still unclear. We set out to study contribution variants for across lifespan conducting meta-analyses genome-wide...
The group of standardization and protocols the Spanish Society Parenteral Enteral Nutrition (SENPE) published in 2011 a consensus document SENPE/SEGHNP/ANECIPN/SECP on enteral access for paediatric nutritional support. Along lines this document, we have developed another adult patients to homogenize clinical practice improve quality care age group. working included health professionals (nurses, dietitians doctor) with extensive experience nutrition access. We tried find scientific evidence...