A5103700105- Corporate Finance and Governance
- Auditing, Earnings Management, Governance
- Molecular Biology Techniques and Applications
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Acute Myeloid Leukemia Research
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Cancer-related molecular mechanisms research
- Chronic Myeloid Leukemia Treatments
- Oral microbiology and periodontitis research
- RNA modifications and cancer
- Corporate Taxation and Avoidance
- RNA Interference and Gene Delivery
- Financial Markets and Investment Strategies
- Histone Deacetylase Inhibitors Research
- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Private Equity and Venture Capital
- Mesenchymal stem cell research
- Advanced biosensing and bioanalysis techniques
- Cytomegalovirus and herpesvirus research
- Financial Reporting and Valuation Research
- Taxation and Compliance Studies
- Bioactive Natural Diterpenoids Research
SUNY New Paltz
2021-2024
Xi'an Jiaotong University
2024
State Grid Corporation of China (China)
2023
First Affiliated Hospital of Jiamusi University
2022
Tianjin Foreign Studies University
2010-2021
Soochow University
2021
Kyoto University
2021
Chengdu Women's and Children's Central Hospital
2021
University of Electronic Science and Technology of China
2021
University of Chinese Academy of Sciences
2021
Acquisition of additional genetic and/or epigenetic abnormalities other than the BCR / ABL fusion gene is believed to cause disease progression in chronic myeloid leukemia (CML) from phase blast crisis (BC). To gain insights into underlying mechanisms BC, we screened DNA samples CML patients during transformation for mutations a number transcription factor genes that are critical myeloid–lymphoid development. In 85 cases transformation, identified two new coding region GATA-2 , negative...
Journal Article Chlorantraniliprole Resistance in the Diamondback Moth (Lepidoptera: Plutellidae) Get access Wei Gong, Gong 1Key Laboratory of Pesticide Toxicology and Application Technique, College Plant Protection, Shandong Agricultural University, Tai'an 271018, P. R. China. Search for other works by this author on: Oxford Academic PubMed Google Scholar Hui-Hui Yan, Yan Li Gao, Gao 2Medical Department Central Hospital, 271000, Yun-Yun Guo, Guo 3Agricultural Animal Bureau Pingliang, Gansu...
The application of RNA interference (RNAi) as a research and therapeutic tool depends on its ability to silence genes in sequence-specific manner. Recent studies have reported that the effective knockdown can be achieved by multiple short hairpin RNAs (shRNAs) single vector. Moreover, this approach depress several simultaneously. However, current methods for construction shRNA vectors often suffer from vector instability are time-consuming. Here, we describe simple, quick low-cost construct...
The refractoriness of acute promyelocytic leukemia (APL) with t (11;17)(q23;q21) to all- trans retinoic acid (ATRA)-based therapy concerns clinicians and intrigues basic researchers. By using a murine leukemic model carrying both zinc finger/retinoic receptor-α ( PLZF/RARα ) RARα/PLZF fusion genes, we discovered that 8-chlorophenylthio adenosine-3′, 5′-cyclic monophosphate (8-CPT-cAMP) enhances cellular differentiation improves gene -activation by ATRA in blasts. Mechanistically, combination...
The ZNF268 gene was originally isolated from an early human embryo cDNA library. Several different transcripts have been for the and developmental expression studies suggest that plays a role in development of fetal liver differentiation blood cells. In our effort to study functions organs during pathogenesis, we now identified 3 novel splicing isoforms, ZNF268e, ZNF268f ZNF268g, tissues tumor derived cell lines. 8 alternatively spliced mRNAs discovered so are predicted encode protein...
Porphyromonas gingivalis, as a major pathogen of periodontitis, could rapidly adhere to and invade host gingival epithelial cells (GECs) for the induction infection. One ATP-binding cassette (ABC) transporter gene was found be upregulated during this infection process, however, molecular mechanisms remain unclear. In study, we systemically investigated messenger RNA level changes all ABC family genes in P. gingivalis while being internalized within GECs by real-time polymerase chain...
Abstract The human ZNF300 gene is a member of the KRAB/C2H2 zinc finger family, members which are known to be involved in various developmental and pathological processes. Here, we show that encodes 68-kDa nuclear protein binds DNA sequence-specific manner. binding site, C(t/a)GGGGG(c/g)G, was defined via random oligonucleotide selection assay, site further confirmed by electrophoretic mobility shift assays. A potential found promoter region IL-2Rβ gene. results assays indicated bound vitro....
Porphyromonas gingivalis, the key etiologic agent of periodontitis, can be classified into six types (I to V and Ib) based on fimA genes that encode FimA (a subunit fimbriae). Accumulated evidence indicates P. gingivalis expressing Type II fimbriae (Pg-II) is most frequent isolate from severe periodontitis cases more virulent than other gingivalis. However, during Pg-II infection process, which specific virulence factors play role still unclear. In this study, we examined capabilities three...
This study was purposed to investigate the antitumor effect of oridonin on human multiple myeloma cell line U266 and its possible mechanism. The CCK-8 test used determine inhibitory proliferation cells. morphological changes cells were observed under optical microscope. apoptosis rate detected by flow cytometry. mRNA levels FGFR3, BCL2, CCND1 MYC genes quantified using real-time quantitative PCR method, protein MYC, CCND1, FGFR3 P53 Western blot. results showed that obviously inhibited...
This study examined the association between corporate cryptocurrency activities and tax avoidance outcomes, utilizing data from US public firms covering period 2015 to 2023. Financial were sourced Compustat, while details regarding manually extracted 10-K 10-Q filings. Our analysis employed a fixed-effects regression model examine impact of these on cash effective rates (ETR). The findings indicate that engaged in tend have lower ETR compared with those without such involvement. Notably,...