A5075962208- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Viral Infections and Vectors
- Tuberculosis Research and Epidemiology
- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- Animal Virus Infections Studies
- Diagnosis and treatment of tuberculosis
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
- COVID-19 epidemiological studies
- Pregnancy and preeclampsia studies
- Cancer-related molecular mechanisms research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Hepatitis Viruses Studies and Epidemiology
- Child Nutrition and Water Access
- Cardiovascular Disease and Adiposity
- Renal cell carcinoma treatment
- Acute Lymphoblastic Leukemia research
- Pregnancy and Medication Impact
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Southern Medical University
2016-2025
Guangzhou University of Chinese Medicine
2020-2025
Guangzhou Medical University
2023-2025
University of South China
2024-2025
Fujian Institute of Research on the Structure of Matter
2024
Chinese Academy of Sciences
2024
Tongji University
2024
Tongde Hospital of Zhejiang Province
2021
Jinan University
2020
Neonatal disorders (ND) are a significant global health issue. This article aimed to track the trends of neonatal in 204 countries/territories from 1990 2019.Data was explored Global Burden Disease study 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were calculated quantify their specific causes, mainly included preterm birth (NPB), encephalopathy due asphyxia trauma (NE), sepsis other infections (NS), hemolytic disease jaundice (HD).In 2019, there 23,532.23...
Understanding the Li-ions conduction network and transport dynamics in polymer electrolyte is crucial for developing reliable all-solid-state batteries. In this work, advanced nano- X-ray computed tomography combined with Raman spectroscopy solid state nuclear magnetic resonance are used to multi-scale qualitatively quantitatively reveal ion of poly(ethylene) oxide (PEO)-based (from atomic, nano macroscopic level). With clear mapping microstructural heterogeneities segments, aluminium-oxo...
Abstract Background The patterns of leukemia burden have dramatically changed in recent years. This study aimed to estimate the global trends leukemia‐related death and disability‐adjusted life‐years (DALYs) from 1990 2017. Methods data was acquired latest version Global Burden Disease (GBD) study. Estimated annual percentage changes (EAPCs) were calculated trend age‐standardized rate (ASR) DALYs due its main subtypes Results Globally, numbers 347.58 × 10 3 (95% uncertainty interval [UI] =...
Abstract Background Antituberculosis-drug resistance is an important public health issue, and its epidemiological patterns has dramatically changed in recent decades. This study aimed to estimate the trends of multidrug-resistant tuberculosis (MDR-TB), which can be used inform strategies. Methods Data were collected from Global Burden Disease 2017. The estimated annual percentage changes (EAPCs) calculated assess MDR-TB burden at global, regional, national level 1990 2017 using linear...
Objectives Intimate partner violence (IPV) against women remains a major global public health problem with harmful consequences for individuals and society. People’s lifestyles have been greatly affected by the COVID-19 pandemic. This study investigated prevalence of relationship between IPV anxiety depression in pregnant Chinese during Design Cross-sectional study. Setting investigation was conducted Shenzhen City, Guangdong Province, China from 15 September to December 2020. Participants A...
Abstract Preeclampsia (PE) is considered as a disease of placental origin. However, the specific mechanism abnormalities remains elusive. This study identified thrombospondin‐1 (THBS1) downregulated in preeclamptic placentae and negatively correlated with blood pressure. Functional studies show that THBS1 knockdown inhibits proliferation, migration, invasion increases cycle arrest apoptosis rate HTR8/SVneo cells. Importantly, silencing induces necroptosis cells, accompanied by release...
Picornaviruses, common infectious agents in humans and various animal species, pose significant health threats. Conventional monoplex PCR is widely employed laboratory diagnostics but relatively time-intensive laborious. In this study, we developed a multiplex TaqMan probe-based real-time quantitative (qPCR) assay for the rapid simultaneous detection of kobuvirus, parechovirus B, rosavirus B hunnivirus murine rodent shrew samples. The approach demonstrated high sensitivity specificity, with...
Abstract Aim Recent findings suggest that mitigating ferroptosis could serve as an effective strategy for treating inflammation. This study aimed to investigate the role enhancer of zeste homologue 2 ( EZH2 ) mediated signal transducer and activator transcription 3 stat3 methylation plays in modulation pulpitis. The results offer potential advancements therapeutic approaches pulpitis provide new insights strategies managing this condition. Methodology Bioinformatics analysis combined with...
Background: Higher visit-to-visit cholesterol has been associated with cognitive decline. However, the association between long-term increase or decrease in and decline remains unclear. Methods: A total of 4,915 participants aged ≥45 years normal cognition baseline were included. The divided into four groups, namely low–low, low–high, high–low, high–high, according to diagnostic thresholds (TC), non-high-density lipoprotein (NHDL-C), low-density cholesterol, high-density (HDL-C) after 4...
Berberine has received rising attention for its application in cardiovascular disease because of relationship with inflammation. The endothelial NLRP3 inflammasome triggers inflammatory vascular injury which would lead to disease. Endothelial calcium signalling plays a crucial role both the activation and cells dysfunction. However, efficacy BBR on remains unknown.In this study, we focused pathway determine whether regulates junction function injury.The integrity proteins VE-cadherin (VEC)...
A recent study has reported that patients with nonalcoholic fatty liver disease (NAFLD) are more susceptible to coronary microvascular dysfunction (CMD), which may predict major adverse cardiac events. However, little is known regarding the causes of CMD during NAFLD. In this study, we aimed explore role hepatic small extracellular vesicles (sEVs) in regulating endothelial microvessels NAFLD.We established two murine NAFLD models by feeding mice a methionine-choline-deficient (MCD) diet for...
Background: Elderly population is considered at high risk for pneumococcal diseases. The vaccine coverage presents extremely low among elderly people in China. However, the serious event of COVID-19 drives interest vaccine, prompting us investigating willingness to accept 23-valent polysaccharide (PPSV23) and influencing factors aged over 60 years during pandemic. Methods: A cross-sectional study was employed using a self-administered questionnaire Shenzhen City China, elaborating toward...
Rosavirus is a newly discovered member of the family Picornaviridae that was initially detected in wild rodents and subsequently children with diarrhoea. Nevertheless, there significant gap our understanding geographical distribution, phylogenetic relationships, evolutionary patterns, transmission rosaviruses. To address these issues, we analysed 434 shrews from five different species were collected southern China. Using PCR screening faecal samples, rosaviruses Norway rats (Rattus...
Urban rodents and house shrews are closely correlated in terms of location with humans can transmit many pathogens to them. Hepatitis E has been confirmed be a zoonotic disease. However, the potential rat HEV is still unclear. The aim this study was determine prevalence genomic characteristics hepatitis virus (HEV) shrews.We collected total 788 animals from four provinces China. From 614 murine rodents, 20.19% liver tissue samples 45.76% fecal were positive for HEV. 174 (Suncus murinus),...
The present study focused on the adverse events following vaccination against hepatitis B virus (HBV) in Guangdong Province of China between 2005 and 2017. In total, more than 88 million doses HBV vaccine were administered during period. A total 3115 immunization (AEFI) related to occurred, with an overall incidence 35.39 per doses. Of these, 1801 cases male, 1314 female; 74.01% (2376/3115) occurred children aged less 2 years; 56.05% (1746/3115) classified as common reactions; 30.37%...