A5052301368- Cleft Lip and Palate Research
- Maternal and Perinatal Health Interventions
- Child Abuse and Trauma
- Child Nutrition and Feeding Issues
- Maternal Mental Health During Pregnancy and Postpartum
- Dysphagia Assessment and Management
- Bone and Dental Protein Studies
- Pediatric health and respiratory diseases
- Photosynthetic Processes and Mechanisms
- Breastfeeding Practices and Influences
- Exercise and Physiological Responses
- Nasal Surgery and Airway Studies
- Ear Surgery and Otitis Media
- Muscle Physiology and Disorders
- Craniofacial Disorders and Treatments
- Injury Epidemiology and Prevention
- Oral microbiology and periodontitis research
- Sleep and related disorders
- Dental materials and restorations
- Periodontal Regeneration and Treatments
- Indigenous Studies and Ecology
- Plant biochemistry and biosynthesis
- Congenital Ear and Nasal Anomalies
- Antioxidant Activity and Oxidative Stress
- Salivary Gland Disorders and Functions
Tohoku University
2008-2025
Tohoku University Hospital
2019-2025
Niigata University
2000
Functional constipation is the most common gastrointestinal disorder during childhood. Oral stimulation (mastication and toothbrushing) reportedly improves bowel movements, but association between daily toothbrushing behavior functional remains unknown. Data (n = 83,660) from fetal records 104,059) in Japan Environment Children's Study, an ongoing prospective birth cohort, were analyzed to investigate impact of frequency on childhood, using ROME III diagnostic criteria. After multiple...
Sports-related dental injuries, such as tooth fracture, loosening, and avulsion, are a major concern among young athletes because they directly impair oral function. Although the preventive efficacy of mouthguards has been well established, prevalence sports-related injuries remains high athletes. The aim this study is to identify variables contributing risk by conducting survey on large population in Miyagi prefecture. A cross-sectional was conducted with school-aged (aged 6–15 years, n =...
Cleft lip and/or palate is among the most prevalent congenital birth defects, and negatively affects maternal psychological status may consequently result in higher prevalence of child maltreatment. However, association childbirths infants with cleft emotional involvement still remains unclear. We examined between mother-to-infant bonding, using data from Japan Environment Children's Study, a nationwide cohort study.A cross-sectional study jecs-an-20,180,131 dataset was performed. A total...
ABSTRACT Occlusal forces may induce the physiological teeth migration in humans, but there is little direct evidence. Rat molars are known to migrate distally during aging, possibly caused by occlusal forces. The purpose of this study was determine if a reduction occlusion would decrease and affect associated periodontal structures such as cementum. To reduce forces, right upper first molar (M1) juvenile rats extracted. transition position second (M2) formation M2 cementum followed aging....
Root resorption lacunae are principally formed by odontoclasts. While these cells develop from the same origin as osteoclasts, odontoclasts normally have fewer nuclei and a less clear zone compared with osteoclasts. We therefore, hypothesized that possess differentiation in matrix characteristics than To test our hypothesis, we TRAP-positive area expression patterns of two important proteolytic enzymes, cathepsin K metalloproteinase-9 (MMP-9), between focused on physiological root rat molar,...
Abstract The gut environment, including the microbiota and its metabolites short-chain fatty acids (SCFA), is essential for health maintenance. It considered that functional recovery treatment masticatory dysphagia affects composition of microbiota, indicating habitual mastication, depending on hardness food, may affect environment. However, impact chronic powdered diet feeding colonic condition motility remains unclear. Here, we evaluated various features in mice fed with diets a long-term...
A new biosynthetic intermediate of ABA, (2Z,4E)-γ-ionylideneacetaldehyde, was isolated from young mycelia Cercospora cruenta. Under an 18O2 atmosphere, oxygen atom this endogenous aldehyde exclusively labeled. Similarly, three 18O atoms were incorporated into the ABA molecule recovered after prolonged incubation; selectively labeled one carboxyl and two on ring portion ABA. feeding experiment with [1-13C]glucose proved exclusive operation mevalonate pathway for formation both β-carotene....
A Chiralcel OJ column was used to determine the absolute configuration of naturally occurring α-ionylideneacetic acid from Cercospora rosicola and γ-ionylideneacetic C. cruenta as (R) enantiomers in accordance with their biosynthetic product, (S)-ABA. Both [1, 2-13C2]-α acids were prepared fed cruenta. Six combinations feeding experiments comparatively unequivocally demonstrated stereoselectivity conversions, including stepwise hydroxylation at C-1′ 4′. Enzymatic isomerization γ...
The cytokine interleukin-6 (IL-6) is released from working skeletal muscles and reportedly plays key roles in their glucose homeostasis. However, it unclear whether IL-6 such the masseter muscle (MM), which important normal pathological chewing behaviors, as bruxism and/or prolonged clenching. When restrained (R+) a narrow cylinder blocked at front end with thin plastic strip, mouse gnaws away (G+) strip to escape. absolute weight of gnawed serves an index MM activity. Using this model, we...
Abstract Objectives Daily toothbrushing behaviour is very effective for the prevention of early childhood dental caries (ECC), but mostly dependent upon parental management. Intrapersonal association between lower frequency and depression well known; however, impact maternal postpartum on child within mother‐child dyad remains unknown. The aim this study was to determine prevalence in children aged two years. Methods A secondary analysis a data set from Japan Environment Children's Study...
Abstract Cleft lip and/or palate (CL/P), the most prevalent congenital anomaly, is understood to negatively affect a wide range of child development. Since concept remains controversial, because published work from cross‐sectional studies, we examined neurodevelopmental trajectories in participants with CL/P through longitudinal comparison general population during early childhood using data nationwide birth cohort study Japan. The linear mixed models for each domain Ages and Stages...
Daily toothbrushing prevents early childhood caries, but reinforcement depends on facilitative parenting behaviours. Mother-to-infant bonding, the maternal affection towards infant, is an environmental factor that strongly influences parenting.This study examined association between bonding and children's daily frequency.The sample consisted of 83 954 mother-infant pairs at two years postpartum, derived from initial JECS (cohort study), which included 104 062 foetuses. Maternal disorders...
Introduction Cleft lip and/or palate (CL/P), the most prevalent congenital anomaly, has been associated with higher rates of child maltreatment. In particular, presence cleft more an impact on external appearance and may increase risks negative health outcomes such as parental postpartum depression; however, this concept remains controversial. Item #10 Edinburgh Postpartum Depression Scale is assessment self-harm ideation, its in mothers merits risk assessments emergent issue that affect...
Bruxism, the involuntary activity of masticatory muscles, is common among individuals with autism spectrum disorders (ASD). Although bruxism bidirectionally associated sleep issues, whether an infant’s duration contributes to development remains unknown. In this study, a dataset (n = 83,720) obtained from Japan Environment and Children’s Study, nationwide birth cohort was subjected multiple imputations using logistic regression analysis adjustments for several maternal child-related...
Abstract Background: Cleft lip and/or palate is among the most prevalent congenital birth defects, and negatively affects maternal psychological status may consequently result in higher prevalence of child maltreatment. However, association cleft childbirths with bonding disorders still remains unclear. We examined between childbirth mother-to-infant bonding, using data from Japan Environment Children's Study, a nationwide cohort study. Methods: A cross-sectional study jecs-an-20180131...
Abstract Background: Cleft lip and/or palate is among the most prevalent congenital birth defects, and negatively affects maternal psychological status may consequently result in higher prevalence of child maltreatment. However, association childbirths infant with cleft emotional involvement still remains unclear. We examined between mother-to-infant bonding, using data from Japan Environment Children's Study, a nationwide cohort study. Methods: A cross-sectional study jecs-an-20180131...
Abstract Background Cleft lip and/or palate (CL/P) is among the most prevalent congenital birth defects. They negatively affect maternal psychological status and may consequently result in higher prevalence of child maltreatment. However, association CL/P births with bonding disorders still remains unclear. To address this question, we examined impact on mother-to-infant bonding, using nationwide cohort study, Japan Environment Children's Study. Methods This study was conducted as a...
Abstract Background: Cleft lip and/or palate is among the most prevalent congenital birth defects, and negatively affects maternal psychological status may consequently result in higher prevalence of child maltreatment. However, association childbirths infants with cleft emotional involvement still remains unclear. We examined between mother-to-infant bonding, using data from Japan Environment Children's Study, a nationwide cohort study. Methods: A cross-sectional study jecs-an-20180131...