A5100442169- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Fetal and Pediatric Neurological Disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Congenital Anomalies and Fetal Surgery
- Pregnancy and Medication Impact
- Neonatal Respiratory Health Research
- Maternal Mental Health During Pregnancy and Postpartum
- Food Allergy and Anaphylaxis Research
- Parvovirus B19 Infection Studies
- Sports injuries and prevention
- Maternal and Perinatal Health Interventions
- Knee injuries and reconstruction techniques
- Maternal and fetal healthcare
- Reproductive tract infections research
- Cardiovascular Effects of Exercise
- Breastfeeding Practices and Influences
- Vitamin D Research Studies
- Air Quality and Health Impacts
- Cardiovascular Issues in Pregnancy
CHA Gangnam Medical Center
2013-2024
CHA University
2013-2024
Kangbuk Samsung Hospital
2015-2016
Sungkyunkwan University
2015-2016
Myongji Hospital
2010
Catholic Kwandong University
2010
Background Although cesarean delivery and prenatal exposure to antibiotics are likely affect the gut microbiome in infancy, their effect on development of atopic dermatitis (AD) infancy is unclear. The influence individual genotypes these relationships also To evaluate with a prospective birth cohort study whether section, antibiotics, susceptible act additively promote AD infancy. Methods Cohort for Childhood Asthma Allergic Diseases (COCOA) was selected from general Korean population. A...
Our primary objective was to establish a cutoff value for the soluble fms-like tyrosine kinase 1(sFlt-1)/placental growth factor (PlGF) ratio measured using Elecsys assay predict late-onset preeclampsia in low-risk pregnancies. secondary evaluate ability of combination models data, second trimester uterine artery (UtA) Doppler ultrasonography measurements, and serum fetoplacental protein levels used Down's syndrome screening, preeclampsia.This prospective cohort study included 262 pregnant...
Abstract Background/Objective Healthy weight maintenance before and during pregnancy has a significant effect on outcomes; however, there are no specific guidelines for gestational gain in pregnant Korean women. Therefore, we investigated the impact of pre-pregnancy body mass index (BMI) risk maternal infant complications Methods Study participants comprised 3454 singleton women from Pregnancy Outcome who had baseline examination outcome data. Maternal BMI were categorized according to...
Purpose Previous studies suggest that the concentration of 25-hydroxyvitamin D [25(OH)D] in cord blood may show an inverse association with respiratory tract infections (RTI) during childhood. The aim present study was to examine influence 25(OH)D concentrations on infant RTI a Korean birth cohort. Methods levels obtained from 525 newborns prospective COhort for Childhood Origin Asthma and allergic diseases were examined. primary outcome variable interest prevalence at 6-month follow-up, as...
Postpartum depression (PPD) can negatively affect infant well-being and child development. Although the frequency risk factors of PPD symptoms might vary depending on country culture, there is limited research these among Korean women. This study aimed to elucidate potential throughout pregnancy help improve screening prevention in
Herlyn-Werner-Wunderlich syndrome is a rare Mullerian ductal anomaly that characterized by the presence of hemivaginal septum, didelphic uterus and ipsilateral renal agenesis. It generally difficult to diagnose uterine malformation before menarche owing its small size. Therefore, follow-up study very important for confirming in girls with We report patient agenesis microscopic hematuria, who showed symptoms menarche. A eventually revealed didelphys obstruction. biopsy proved hematuria was...
To compare the quality of two different imaging methods, three-point Dixon (mDixon) and fast spin-echo (FSE) T2 weighted image (T2WI) [and fat suppression (FS) T2WI], to assess utility mDixon for knee joint pathology.This retrospective study included 66 patients who underwent both FSE T2WI (and FS T2WI) joint. Signal-to-noise ratio (SNR) contrast-to-noise (CNR) sequences at articular cartilage ligament were measured. Two radiologists independently evaluated anatomic identification score...
A Birth Cohort Study (COCOA) Previous studies suggest that maternal characteristics may be associated with neonatal outcomes.However, the influence of on birth weight (BW) has not been adequately determined in Korean populations.We investigated associations between and BW a sample 813 women living Seoul metropolitan area, Korea recruited using data from prospective hospital-based COhort for Childhood Origin Asthma allergic diseases 2007 2011.The mean age at delivery was 32.3 ± 3.5 yr...
The purpose of the study was to examine relationship between parameter representing ovarian reserve and fetal aneuploidy in early spontaneous miscarriage.A multicenter retrospective cohort performed patients who were diagnosed with pregnancy loss (≤13 gestational weeks) examined for karyotype at CHA Gangnam Medical Center, Bundang Gumi Center January 2011 December 2012. Karyotyping by Genetic Laboratory Fertility Center. records reviewed demographics, analysis hormonal assay including...
To compare the reliability of two recently reported MR grading systems cervical neural foraminal stenosis (CNFS) and their correlation with clinical manifestations.We evaluated 188 patients (male : female = 80 108; mean age 41 years) who visited our institution underwent oblique sagittal MRI spine. Two radiologists findings for presence grade CNFS at narrowest point, (Park, Kim mKim systems) suggested by Park et al al. More than one positive neurologic sign more symptom was considered a...
Cord Blood Cellular Proliferative Response as a Predictive Factor for Atopic Dermatitis at 12 MonthsSince the risk of developing allergic disease increases in individuals exposed to allergens previously, even during neonatal period, immunologic status fetus may be important subsequent development allergy.We evaluated fetal factors predict atopic dermatitis (AD) months 412 infants COhort Childhood Origin Asthma and Allergic Diseases (COCOA) general Korean population.Cord blood mononuclear...
Purpose: Chromosomal microarray (CMA) is a high-resolution technique that can identify submicroscopic chromosomal aberrations or copy number variants (CNVs).We aimed to analyze the frequency of significant CNVs according involved organ systems in fetuses with ultrasound-detected abnormalities.Materials and Methods: This study was retrospective observational study.We conducted between April 2019 July 2023, including abnormal ultrasound findings normal karyotyping results.We analyzed results...
Prenatal maternal stress affects offspring's atopic dermatitis (AD) development, which is thought to be mediated by the oxidative stress. We aimed evaluate difference in leukocyte telomere length (LTL), a marker for exposure stress, according prenatal and later AD development.From birth cohort (the COhort Childhood Origin of Asthma allergic diseases) that had displayed good epidemiologic association between development offspring, we selected 68 pairs samples from 4 subject groups based on...
Purpose: Although home renovation exposure during childhood has been identified as a risk factor for the development of allergy, there is limited information on association between prenatal to and cord blood (CB) IgE response.The aims this study were identify effect CB levels, investigate whether interacts with neonatal genes can be modified by maternal atopy.Methods: This included 1,002 mother-neonate pairs from COhort Childhood Origin Asthma allergic diseases (COCOA).Prenatal environmental...
The aim of this study was to evaluate the predictive value anti-Mullerian hormone (AMH) level for early pregnancy loss and compare significance AMH age as prognostic factors in subfertile women. outcome 848 patients confirmed with intrauterine pregnancies by ultrasound within 1 year measuring serum were retrospectively analyzed. Among patients, 206 women diagnosed loss. mean 35.66 ± 3.61 years (range: 26–46 years), 2.95 1.89 0.14–8.82 ng/mL). There no significant differences gravidity,...
The aim of this research is to investigate the risk factors during pregnancy affect abnormal lipid profiles in women with early postpartum period. This was a single-center retrospective study including 869 who delivered between December 2017 and May 2019. We collected total cholesterol levels, both at 24-28 GWs 1 month before delivery. Lipid such as cholesterol, high-density lipoprotein (HDL), triglyceride (TG) low-density (LDL) 6 weeks after delivery were retrieved. Subjects categorized...
Extravillous trophoblast cells (EVTs) secreted by the uterine cavity may help overcome limitations associated with prenatal testing currently in use. EVTs are isolated using a routine safe liquid-based Pap test (called ThinPrep); however, ThinPrep solution contains alcohol that hinders isolation of intact EVTs. We compared trophoblastic cell efficiency two different methods fixation: Thinprep (pre-fixation method) and formalin (post-fixation method). analyzed from 20 pregnant women (5-20...
Abstract We investigated the predictive value of soluble fms-like tyrosine kinase-1 (sFlt-1)-to-placental growth factor (PlGF) ratio for poor neonatal outcomes SGA neonates in absence preeclampsia. This prospective cohort study included 530 singleton pregnant women who attended a prenatal screening program at single institution. The sFlt-1/PlGF values 24 to 28 +6 weeks and 29 36 gestation were analyzed compared between control group (subdivided as with normal outcomes). After 22 preeclampsia...
This study was designed to assess the effect of inflatable obstetric belts on uterine fundal pressure in management second stage labor. One hundred twenty-three nulliparas with a singleton cephalic pregnancy at term were randomized. Standard care performed control group, and by Labor Assister (Baidy M-420/Curexo, Inc., Seoul, Korea) utilized addition standard active group. The is an that synchronized apply uniform during contraction. 62 women group spent less time labor when compared 61...
Incidence of whooping cough is increasing in Korea. Since 2011, occurrence among adolescents and adults has risen putting vulnerable neonates at risk. National immunization guidelines now include Tdap (tetanus toxoid, reduced diphtheria acellular pertussis) vaccination during pregnancy as a cocooning strategy (i.e., vaccinating contact with neonates). This study assessed post-marketing (Boostrix®, GSK, Belgium) vaccine safety subjects ≥ 10 years.This open, non-comparative multi-center was...
To compare image quality between three-dimensional volume isotropic turbo spin echo acquisition (3D VISTA) with the posterior cruciate ligament (PCL) view and two-dimensional (2D) fast (FSE) for evaluation of PCL injury.This retrospective study included 60 patients clinical suspicion injury who underwent both 2D FSE 3D VISTA knee January 2015 December 2015. The diagnostic performance each oblique coronal combined images was evaluated sensitivity, specificity accuracy diagnosing a tear....