A5035457024- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Pediatric health and respiratory diseases
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Ferroptosis and cancer prognosis
- Respiratory viral infections research
- Cancer, Hypoxia, and Metabolism
- Bone fractures and treatments
- Pneumonia and Respiratory Infections
- Orthopedic Infections and Treatments
- Immune Response and Inflammation
- Surgical site infection prevention
- Salivary Gland Disorders and Functions
- Respiratory and Cough-Related Research
- Virus-based gene therapy research
- Dental Erosion and Treatment
- MicroRNA in disease regulation
- Vagus Nerve Stimulation Research
- Antibiotics Pharmacokinetics and Efficacy
- Mesenchymal stem cell research
- Medicinal Plants and Bioactive Compounds
- Extracellular vesicles in disease
- Cancer, Lipids, and Metabolism
- Liver Disease and Transplantation
Zunyi Medical University
2016-2024
Kunming Medical University
2017-2024
Tianjin Medical University General Hospital
2020-2023
Chengdu University
2019-2023
Beijing Tongren Hospital
2023
Army Medical University
2020-2022
Tianjin Medical University
2020-2022
Second Affiliated Hospital of Nanjing Medical University
2022
Shaanxi Provincial People's Hospital
2022
Guiyang Medical University
2022
Objective Lactulose is effective in the treatment and prevention of overt hepatic encephalopathy (OHE), but there are limited data on its use microbiota relations to minimal (MHE) recovery. The present study aimed assess efficacy lactulose recovery MHE aspects cognitive function, quality life, impact intestinal microbiota. Methods This multicenter, open‐label randomized controlled trial was conducted 11 teaching hospitals China. Participants were randomly allocated a 2:1 basis receive (Gp‐L)...
Objective To determine the epidemiological, clinical and microbiological characteristics, of patients with post-traumatic osteomyelitis extremity fractures, provide evidence-based guidelines for early diagnosis treatment, including empiric antibiotic therapy. Methods Human subject research was performed using institutional review board approved protocols. A retrospective chart conducted on 5,368 diagnosed traumatic fractures from January 1, 2012 to December 31, 2015, identify patients....
To explore the effect of IL-6 on activity and secretory function B cells analyze its clinical indicators efficacy in wAIHA patients. This study included 25 hemolytic patients, 13 remission 10 HCs. Plasma levels various cytokines were detected using CBA. PBMCs extracted from 12 patients divided into three wells, stimulation with + tocilizumab, blank control wells also set. After 48 h vitro cell culture, percentage CD5+CD80+, CD5-CD80+,CD5+CD86+,CD5-CD86+,CD5+IL-10+,CD5-IL-10+B determined by...
Intestinal epithelial cells (IECs) contribute to regulation of gut injury after intestinal ischemia/reperfusion (II/R). Exosomes are well documented deliver bioactive molecules recipient for the purpose modulating cell function. However, role IEC-derived exosomes in damage II/R and underlying mechanisms remain unclear. Here, we investigated effects exosomal miR-23a-3p on using primary IECs that underwent oxygen-glucose deprivation (OGD) as rats. We observed released by attenuated OGD vitro...
Relapsed childhood polymicrobial osteomyelitis associated with dermatophytosis has not been reported in the literature.Here we report on a case of 45-year-old man who had left tibial for 29 years, accompanied by skin fungal infection ipsilateral heel 20 and underwent second operation due to recurrence 6 years ago. The patient history injury from rusty object, which penetrated anterior tibia middle segment causing subsequent bone infection, but was asymptomatic after receiving treatments...
Purpose: To study the effect of galantamine on anti-inflammatory responses in acid aspiration-induced acute respiratory syndrome (ARDS), and underlying mechanism.Methods: Six groups male rabbits (156), i.e., control group, ARDS + (GAL) methyllycaconitine (MLA) vagotomy (Vag) atropine sulfate (ATS) group. model was produced by aspiration. After 4 h, TNF-α, IL-6 IL-1β were assayed lung tissue, while corticosterone levels determined blood. Histopathological lesions wet-to-dry (W/D) weight ratio...
Formulae display:?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax order to improve their display. Uncheck the box turn off. This feature requires Javascript. Click on a formula zoom.
We aimed to investigate whether there is a correlation between AT and pleural effusion in PE patients.
This study aimed to evaluate the underlying pharmacological mechanisms of Apatinib anti-bladder cancer via network pharmacology and experimental verification.Network was used screen possible signaling pathways in bladder cancer, most likely pathway selected for vitro validation. CCK-8 colony formation assay were detect effect on proliferation cells. Hoechst staining flow cytometry detected apoptosis cells induced by Apatinib. Western blot performed distinguish expression levels key...
Objective Autoimmune hemolytic anemia (AIHA) is rare heterogeneous disorder characterized by red blood cell (RBC) destruction via auto-antibodies, and after RBC destroyed, proinflammatory danger-associated molecular patterns including extracellular hemoglobin, heme, iron which causing injury. And oxidative stress represents one of the most significant effects chronic hemolysis. Jianpishengxue keli can improve symptoms patients with kidney disease tumors are beneficial in promoting recovery...
Objective To investigate the clinical features of AIHA/ES patients with clonal Ig/TCR gene rearrangement.Methods rearrangements were measured by BIOMED-2 PCR. 44 primary enrolled in study. Clinical characteristics analyzed and compared between without rearrangement.Results Clonal identified 34.09% (15/44) including 18.18% (8/44) Ig rearrangement 15.91% (7/44) TCR rearrangement. 11.37% (5/44) showed γ rearrangement, 2.27% (1/44) patient β both chain The median ages clonality (8 male 7 female)...
Objective To screen and analyze the micro-Ribonucleic Acid (miRNA) expression profile in B lymphocytes from patients with autoimmune haemolytic anaemia (AIHA) using high-throughput sequencing.Methods Twelve warm (wAIHA) twelve healthy controls (HCs) were enrolled. CD19+ isolated purified magnetic activated cell sorting (MACS). RNA was subsequently extracted these cells a small library created. The miRNA analyzed Beijing Genomics Institute Sequencing 500 (BGISEQ-500), stem-loop real-time...
Objective: To analyze the effects of sequence radiotherapy and chemotherapy on efficacy early-stage extranodal NK/T-cell lymphoma (nasal type, ENKTCL) patients, to provide a quantitative evaluation method for individualized chemotherapy. Methods: The Chinese Lymphoma Collaborative Group (CLCG) collected clinical data 2 008 patients with Ⅰ/Ⅱ ENKTCL who received from January 2000 early September 2019 21 hospitals across country, including 1 417 males 591 females, aged 83 (42±14) years....
Objective To investigate regional characteristics of postoperative Gram-positive/negative bacterial infection and antibiotic resistance following traumatic limb fracture patients in Southwest China, to provide evidence-based guidelines for empiric therapy. Methods All human subject studies were performed using protocols approved by the institutional review board. A retrospective chart was 3, 728 medical records who had been treated extremity from January 2012 2015. Included present...
Caries is the most widespread oral disease threatening human health, especially early childhood caries, traditional treatment a big challenge in clinical. In order to prevent enamel demineralization, casein phosphopeptides (CPPs) incorporation with mesoporous 58S bioactive glass (M58S) was used evaluate remineralization ability vitro . By sol–gel method M58S synthesized and showed good pore size volume. simulated fluid (SOF), 3%wt CPPs/M58S better mineralized ability, remineralized layer...
Objective To study the clinical effect of Zhuang medicine line point moxibustion in treatment psoriasis vulgaris. Methods 60 vulgaris patients qualified subjects were randomly divided into observation group and control group.The was given routine psoriasis.The points on basis two groups treated for four courses.The efficacy compared, changes PASI score DLQL at different time periods compared. Results The total effective rate 76.7%, which higher than 50.0% (χ2=3.125, P<0.05)....