A5024780103- Child Nutrition and Water Access
- Global Maternal and Child Health
- Poverty, Education, and Child Welfare
- Child Nutrition and Feeding Issues
- Iron Metabolism and Disorders
- Food Security and Health in Diverse Populations
- Trace Elements in Health
- Breastfeeding Practices and Influences
- Obesity, Physical Activity, Diet
- Pregnancy and preeclampsia studies
- Healthcare Systems and Reforms
- Public Health and Nutrition
- Hemoglobinopathies and Related Disorders
- Gestational Diabetes Research and Management
- Interprofessional Education and Collaboration
- Birth, Development, and Health
- Microfluidic and Bio-sensing Technologies
- Clinical Nutrition and Gastroenterology
- Healthcare Systems and Practices
- Neonatal Health and Biochemistry
- Thyroid Disorders and Treatments
- Infant Nutrition and Health
- Mental Health and Patient Involvement
- Antioxidant Activity and Oxidative Stress
- Biosensors and Analytical Detection
Mali-Folkecenter
2022-2024
International Rescue Committee
2024
Johns Hopkins University
2023
University of California, Davis
2016-2021
United Nations Children's Fund Niger
2016-2021
Institut de Recherche en Sciences de la Santé
2012-2017
Helen Keller International
2015-2016
Centre Hospitalier Universitaire Yalgado Ouédraogo
2002
Abstract Growth faltering in children (low length for age or low weight length) during the first 1,000 days of life (from conception to 2 years age) influences short-term and long-term health survival 1,2 . Interventions such as nutritional supplementation pregnancy postnatal period could help prevent growth faltering, but programmatic action has been insufficient eliminate high burden stunting wasting low- middle-income countries. Identification windows population subgroups on which focus...
Introduction To design effective national diarrhea control programs, including oral rehydration solution (ORS) and therapeutic zinc supplementation, information is needed on local perceptions of illness, external care seeking behaviors, home treatment practices. Methods A cross-sectional, community-based household survey was conducted in the Orodara Health District, Burkina Faso. Caregivers 10,490 children <27 months were interviewed to assess child prevalence related Characteristics...
A simplified, combined protocol was created that admits children with a mid-upper-arm circumference (MUAC) of <125 mm or edema to malnutrition treatment ready-to-use therapeutic food (RUTF) involves prescribing two daily RUTF sachets MUAC < 115 and one sachet those ≤ 125 mm. This previously shown result in non-inferior programmatic outcomes compared standard treatment. We aimed at observing its effectiveness routine setting scale, including via delivery by community health workers (CHWs)....
Anemia and micronutrient (MN) deficiencies in pregnant women are associated with adverse pregnancy outcomes. In Niger, 58.6% of anemic; however, MN statuses unknown. The study objectives were to estimate the prevalence among Zinder, Niger explore risk factors. Pregnant living randomly selected rural villages (n = 88) included. Capillary venous blood samples 770) analyzed for hemoglobin (Hb) plasma ferritin, soluble transferrin receptor (sTfR), zinc (pZn), retinol binding protein (RBP),...
Deficiencies of vitamin A, iron, and iodine are major public health concerns in many low- middle-income countries, but information on their status populations is often lacking due to high costs logistical challenges associated with assessing micronutrient status. Accurate, user-friendly, low-cost analytical tools needed allow large-scale population surveys We present the expansion a 7-plex protein microarray tool for simultaneous measurement up seven biomarkers relevance assessment key...
The World Health Organization recommends iron and folic acid (IFA) supplementation for pregnant women. high prevalence of anaemia among women in Niger warrants better understanding the utilization antenatal care (ANC) IFA. We aimed to assess factors associated with ANC coverage adherence IFA recommendation Pregnant (n = 923) from 64 randomly selected villages within catchment area 12 health centres were interviewed during a baseline household survey Zinder, Niger. 60.1% 43.6%, respectively....
Pregnant and lactating women in rural Niger are at high risk for inadequate intakes of multiple micronutrients. Thus, 24 h dietary recalls were conducted analyzed this population (n = 202). Using linear programming analyses, micronutrient gaps women’s diets identified, food-based recommendations (FBR) to improve adequacy developed, various supplementation strategies modelled. Energy below estimated requirements, and, most micronutrients, >50% intakes. Linear analyses indicated it would be...
The present study aimed to determine the 6-month incidence of relapse and associated factors among children who recovered from acute malnutrition (AM) following mid-upper arm circumference (MUAC)-based simplified combined treatment using ComPAS protocol. A prospective cohort 420 had reached a MUAC ≥ 125 mm for two consecutive measures was monitored between December 2020 October 2021. Children were seen at home fortnightly 6 months. overall cumulative [95%CI] into < and/or edema 26.1% [21.7;...
Abstract Treatment of severe acute malnutrition aims at producing quick catch‐up growth in children to decrease their short‐term mortality risk. The extent which is influenced by the amount energy provided unclear. This study assessed whether admission associated with ponderal among mid‐upper arm circumference (MUAC) < 115 mm admission. We conducted a secondary data analysis an operational cohort Mali. were treated simplified protocol providing 1000 kcal/day therapeutic food until MUAC ≥...
To assess iodine status among pregnant women in rural Zinder, Niger and to compare their with the of school-aged children from same households.Seventy-three villages catchment area sixteen health centres were randomly selected participate cross-sectional survey.Salt iodization is mandatory Niger, requiring 20-60 ppm at retail level.A spot urine sample was collected (n 662) one child household 373). Urinary concentration (UIC) assessed as an indicator both groups. Dried blood spots (DBS)...
Abstract Low gestational weight gain (GWG) and low mid‐upper arm circumference (MUAC) are associated with adverse pregnancy outcomes. We aimed to assess the prevalence determinants of GWG MUAC among pregnant women in rural Zinder, Niger. A community‐based survey was conducted 1,384 catchment areas 18 integrated health centers region Weight were measured during an in‐home visit again 1 month later, when haemoglobin concentration micronutrient status also assessed. The defined based on 2009...
Alive & Thrive supported the Government of Burkina Faso to strengthen provision iron and folic acid (IFA) supplementation interpersonal counseling on maternal nutrition breastfeeding through antenatal care (ANC) services community-based contacts in 2 regions.We assessed impacts intensified interventions during ANC compared with standard intervention coverage practices.A cluster-randomized evaluation 40 health center catchment areas control areas. Repeated cross-sectional surveys 2019 2021...
Abstract In Niger, use of antenatal care (ANC) and iron folic acid (IFA) supplements is suboptimal. The objectives this paper are as follows: (a) to conduct formative research understand barriers beliefs among pregnant women related ANC, IFA supplementation, pregnancy outcomes; (b) assess the quality currently provided ANC services; (c) findings guide development programmatic interventions improve coverage services supplementation women. Structured in‐home interviews ( n = 72) focus groups...
Abstract Background Despite an official policy of exemption from health care costs, pregnant women in Niger still face some out-of-pocket costs (OPC) addition to time when they attend antenatal (ANC) services. We aimed to: 1) assess the OPC for woman attending ANC, 2) estimate spent ANC and opportunity cost that time, 3) how affected attendance. Methods Data were obtained a quasi-experimental descriptive study carried out region Zinder, Niger, which compared pre- post-intervention cohorts (...
Background Of two community-based trials among young children in neighboring health districts of Burkina Faso, one found that small-quantity lipid-based nutrient supplements (LNS) increased child growth compared with a non-intervention control group, but zinc supplementation did not the second study. Objectives We explored whether disparate outcomes were associated differences intervention components, household demographic variables, and/or children's morbidity. Methods Children LNS study...
The simplified, combined protocol admits children with a mid-upper-arm circumference (MUAC) of &lt;125 mm or edema to malnutrition treatment ready-to-use therapeutic food (RUTF) prescribing 2 daily RUTF sachets MUAC &lt;115 and 1 sachet those &ge;115 but mm. This has previously been shown result in non-inferior programmatic outcomes compared standard treatment. We aimed at observing its effectiveness routine setting scale, including via delivery by community health workers (CHW)....
A lack of comparative data across laboratories is often a barrier to the uptake and adoption new technologies. Furthermore, generated by different immunoassay methods may be incomparable due harmonization. In this multicenter study, we describe validation experiments conducted in single lab cross-lab comparisons assay results assess performance characteristics Q-plex ™ 7-plex Human Micronutrient Array (7-plex), an that simultaneously quantifies seven biomarkers associated with micronutrient...
Background: Assessment of high-dose vitamin A supplementation (VAS) coverage often relies on postevent (PEC) surveys, but the validity these methods has rarely been evaluated. Objectives: To assess reported VAS and factors associated with missed to investigate reliability results. Methods: During a cross-sectional survey, 10 454 caregivers children <27 months old were asked whether their child had received in past 6 months. 48-week longitudinal study 6232 30 old, every 4 weeks if weeks....
Routine antenatal care (ANC) offers opportunities to receive a broad range of services including support for adequate nutritional pregnant women and their newborns. Alive & Thrive (A&T) aimed strengthen provision iron-folic acid (IFA) supplementation interpersonal counseling on maternal nutrition breastfeeding through government ANC community-based contacts in two regions Burkina Faso. We assessed the impacts intensified interventions during standard (control) intervention coverage...
Background: Adequate nutrition has been cited as one of the most critical components for optimal health outcomes during pregnancy. Women in Burkina Faso and Madagascar experience high rates undernutrition due to lack knowledge, finances, cultural norms, autonomy. Therefore, this study aimed (1) describe typical maternal diets pregnancy Madagascar, (2) understand multilevel factors that influence women’s decision-making, (3) explore extent which women have decision-making autonomy Methods:...
WHO/UNICEF recommend oral rehydration salts (ORS), continued feeding and 10–14 d of Zn supplementation (supp) to treat diarrhea; but preventive supp may provide greater benefit than given only for diarrhea. We compared 3 strategies in 6,426 children 6–30 mo old randomly assigned 1 4 treatments 16, 32 or 48 wk: daily (7mg Zn/d ORS+placebo (Pl) diarrhea), intermittent (10mg 10d every 16wk ORS+Pl therapeutic (daily Pl ORS+20mg diarrhea) control (ORS diarrhea). Home visits were completed weekly;...
Anaemia is prevalent among pregnant women in rural Niger and antenatal care (ANC) attendance suboptimal. We designed a programmatic intervention including community-based behaviour change communication, provision of essential drugs (including iron folic acid (IFA) supplements) quality improvement activities at selected integrated health centres (IHCs).To assess the impact on: (1) utilisation ANC, (2) adherence to daily IFA supplementation (3) prevalence adequate gestational weight gain (GWG)...
Abstract Low coverage of effective nutrition interventions in many high‐burden countries, due to service provision and demand factors, result poor uptake recommended practices outcomes. We examined the factors that influence maternal early breastfeeding determined extent key could improve these two regions Burkina Faso. used household survey data among pregnant ( n = 920) recently delivered women 1840). Multivariable regression analyses were conducted identify determinants a diverse diet...
Abstract Background Admission criteria that treat children with low mid-upper-arm circumference (MUAC), and weight-for-height z -score (WHZ) are not aligned the evidence on which at risk of mortality. An analysis community-based cohort data from Senegal found a combination weight-for-age (WAZ) MUAC identified all near-term death associated severe anthropometric deficits. This study will address whether WAZ <−3 but ≥125 mm benefit therapeutic feeding ready-to-use foods (RUTF) simplified...