Haodong Li
A5101554420- Child Nutrition and Water Access
- Child Nutrition and Feeding Issues
- Long-Term Effects of COVID-19
- Poverty, Education, and Child Welfare
- Advanced Causal Inference Techniques
- Numerical methods for differential equations
- Global Maternal and Child Health
- Differential Equations and Numerical Methods
- Statistical Methods and Inference
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mosquito-borne diseases and control
- Statistical Methods and Bayesian Inference
- Advanced Numerical Methods in Computational Mathematics
- Malaria Research and Control
- Traumatic Brain Injury and Neurovascular Disturbances
- Electromagnetic Simulation and Numerical Methods
- Immunodeficiency and Autoimmune Disorders
- Bladder and Urothelial Cancer Treatments
- Bayesian Modeling and Causal Inference
- Holomorphic and Operator Theory
- Hepatitis Viruses Studies and Epidemiology
- Respiratory Support and Mechanisms
- Livestock and Poultry Management
- RNA and protein synthesis mechanisms
- Spectral Theory in Mathematical Physics
University of California, Berkeley
2020-2024
Berkeley Public Health Division
2023-2024
Xiangtan University
2022-2023
China-Japan Friendship Hospital
2023
Peking University
2023
WuXi AppTec (China)
2011-2012
Sustainable Development Goal 2.2-to end malnutrition by 2030-includes the elimination of child wasting, defined as a weight-for-length z-score that is more than two standard deviations below median World Health Organization standards for growth
Globally, 149 million children under 5 years of age are estimated to be stunted (length more than 2 standard deviations below international growth standards)
Abstract Growth faltering in children (low length for age or low weight length) during the first 1,000 days of life (from conception to 2 years age) influences short-term and long-term health survival 1,2 . Interventions such as nutritional supplementation pregnancy postnatal period could help prevent growth faltering, but programmatic action has been insufficient eliminate high burden stunting wasting low- middle-income countries. Identification windows population subgroups on which focus...
Malaria-elimination interventions aim to extinguish hotspots and prevent transmission nearby areas. Here, we re-analyzed a cluster-randomized trial of reactive, focal (chemoprevention using artemether-lumefantrine and/or indoor residual spraying with pirimiphos-methyl) delivered within 500 m confirmed malaria index cases in Namibia measure direct effects (among intervention recipients m) spillover non-intervention 3 km) on incidence, prevalence seroprevalence. There was no or weak evidence...
Hemagglutinin (HA) of the influenza virus plays a crucial role in early stage viral life cycle by binding to sialic acid on surface host epithelial cells and mediating fusion between envelope endosome membrane for release genomes into cytoplasm. To initiate fusion, pH is lowered acidification causing an irreversible conformational change HA, which turn results fusogenic HA. In this study, we describe characterization HA inhibitor H1N1 viruses, RO5464466. One-cycle time course study MDCK...
Summary Sustainable Development Goal 2.2, to end malnutrition by 2030, includes elimination of child wasting, defined as weight-for-length more than 2 standard deviations below international standards. Prevailing methods measure wasting rely on cross-sectional surveys that cannot onset, recovery, and persistence — key features inform preventive interventions disease burden estimates. We analyzed 21 longitudinal cohorts show is a highly dynamic process onset with incidence peaking between...
Summary Growth faltering (low length-for-age or weight-for-length) in the first 1000 days — from conception to two years of age influences short and long-term health survival. Interventions such as nutritional supplementation during pregnancy postnatal period could help prevent growth faltering, but programmatic action has been insufficient eliminate high burden stunting wasting low- middle-income countries. Future preventive efforts will benefit understanding age-windows population...
Hepadnaviral covalently closed circular DNA (cccDNA) exists as an episomal minichromosome in the nucleus of virus-infected hepatocytes, and serves transcriptional template for synthesis viral mRNAs. To obtain insight on structure hepadnaviral cccDNA minichromosomes, we utilized ducks infected with duck hepatitis B virus (DHBV) a model determined vivo nucleosome distribution pattern by micrococcal nuclease (MNase) mapping genome-wide PCR amplification isolated mononucleosomal DHBV DNA....
Summary Globally 149 million children under five are estimated to be stunted (length more than 2 standard deviations below international growth standards). Stunting, a form of linear faltering, increases risk illness, impaired cognitive development, and mortality. Global stunting estimates rely on cross-sectional surveys, which cannot provide direct information about the timing onset or persistence faltering— key consideration for defining critical windows deliver preventive interventions....
Several recently developed methods have the potential to harness machine learning in pursuit of target quantities inspired by causal inference, including inverse weighting, doubly robust estimating equations and substitution estimators like targeted maximum likelihood estimation. There are even more recent augmentations these procedures that can increase robustness, adding a layer cross-validation (cross-validated estimation double learning, as applied equation approaches, respectively)....
ABSTRACT Post-acute Sequelae of COVID-19 (PASC), also known as Long COVID, is a broad grouping range long-term symptoms following acute infection. An understanding characteristics that are predictive future PASC valuable, this can inform the identification high-risk individuals and preventative efforts. However, current knowledge regarding risk factors limited. Using sample 55,257 participants from National COVID Cohort Collaborative, part NIH Computational Challenge, we sought to predict...
Malaria elimination interventions in low-transmission settings aim to extinguish hot spots and prevent transmission nearby areas. In malaria settings, the World Health Organization recommends reactive, focal targeted area near cases shortly after they are detected. A key question is whether these reduce uninfected or asymptomatic individuals who did not receive interventions. Here, we measured direct effects (among intervention recipients) spillover non-recipients) of delivered within 500m...
Postacute sequelae of COVID-19 (PASC), also known as long COVID, is a broad grouping range long-term symptoms following acute COVID-19. These can occur across biological systems, leading to challenges in determining risk factors for PASC and the causal etiology this disorder. An understanding characteristics that are predictive future valuable, inform identification high-risk individuals preventative efforts. However, current knowledge regarding limited.
Quantifying the heterogeneity of treatment effect is important for understanding how a commercial product or medical affects different subgroups in population. Beyond overall impact reflected parameters like average effect, analysis further reveals details on importance covariates and they lead to impacts. One relevant parameter that addresses such variance across covariate groups, however defined. can also derive variable measure (and rank) much explained by targeted subset covariates. In...
A novel canonical Euler splitting method is proposed for nonlinear composite stiff functional differential-algebraic equations, the stability and convergence of evidenced, theoretical results are further confirmed by some numerical experiments.Especially, its theories can be applied to special cases, such as delay equations integral equations.
Several recently developed methods have the potential to harness machine learning in pursuit of target quantities inspired by causal inference, including inverse weighting, doubly robust estimating equations and substitution estimators like targeted maximum likelihood estimation. There are even more recent augmentations these procedures that can increase robustness, adding a layer cross-validation (cross-validated estimation double learning, as applied equation approaches, respectively)....
<sec> <title>BACKGROUND</title> Postacute sequelae of COVID-19 (PASC), also known as long COVID, is a broad grouping range long-term symptoms following acute COVID-19. These can occur across biological systems, leading to challenges in determining risk factors for PASC and the causal etiology this disorder. An understanding characteristics that are predictive future valuable, inform identification high-risk individuals preventative efforts. However, current knowledge regarding limited....