A5057321813- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- Child Nutrition and Feeding Issues
- Viral Infections and Immunology Research
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Hepatitis Viruses Studies and Epidemiology
- Poverty, Education, and Child Welfare
- Global Maternal and Child Health
- Neutropenia and Cancer Infections
- Bacterial Identification and Susceptibility Testing
- Parasitic Infections and Diagnostics
- Mobile Health and mHealth Applications
- Streptococcal Infections and Treatments
- Reproductive Health and Contraception
- Amoebic Infections and Treatments
- Peripheral Neuropathies and Disorders
- Ovarian function and disorders
- Cell Image Analysis Techniques
- Retinal and Optic Conditions
- Climate Change and Health Impacts
- Forecasting Techniques and Applications
- PARP inhibition in cancer therapy
- Statistical Methods and Bayesian Inference
- Breastfeeding Practices and Influences
Christian Medical College & Hospital
2015-2024
Christian Medical College
2017-2022
National Center for Immunization and Respiratory Diseases
2014
Centers for Disease Control and Prevention
2014
University of Oklahoma Health Sciences Center
2013
Sustainable Development Goal 2.2-to end malnutrition by 2030-includes the elimination of child wasting, defined as a weight-for-length z-score that is more than two standard deviations below median World Health Organization standards for growth
Globally, 149 million children under 5 years of age are estimated to be stunted (length more than 2 standard deviations below international growth standards)
Abstract Growth faltering in children (low length for age or low weight length) during the first 1,000 days of life (from conception to 2 years age) influences short-term and long-term health survival 1,2 . Interventions such as nutritional supplementation pregnancy postnatal period could help prevent growth faltering, but programmatic action has been insufficient eliminate high burden stunting wasting low- middle-income countries. Identification windows population subgroups on which focus...
ABSTRACT Diarrhea causes significant morbidity and mortality in Indian children under 5 years of age. Flies carry enteric pathogens may mediate foodborne infections. In this study, we characterized fly densities as a determinant infectious diarrhea longitudinal cohort 160 urban 80 rural households with 1,274 individuals (27% age) Vellore, India. Household questionnaires on living conditions were completed at enrollment. Fly abundance was measured during the wet dry seasons using ribbons...
The World Health Organization (WHO) recommends six months of exclusive breastfeeding. Despite documented health, social and economic benefits, the practice breastfeeding is quite low information on influencing factors limited especially from slum settlements. Our goal to assess prevalence evaluate associated with early cessation in first life among mothers urban slums Vellore, Southern India. We pooled data three similar birth cohort studies (n = 1088) conducted between 2002 2009....
Abstract Objective To determine the prevalence and risk factors of scrub typhus in Tamil Nadu, South India. Methods We performed a clustered seroprevalence study areas around Vellore. All participants completed factor survey, with seropositive seronegative acting as cases controls, respectively, analysis. After univariate analysis, variables found to be significant underwent multivariate Results Of 721 people participating this study, 31.8% tested seropositive. By after accounting for...
ABSTRACT Background and Aim Acute‐on‐chronic liver failure (ACLF) is a syndrome that develops after an acute insult associated with organ failures high short‐term mortality. Plasma exchange (PLEX) emerging modality for treating ACLF patients. We aimed to evaluate the efficacy of PLEX in ACLF. Methods conducted systematic review meta‐analysis studies comparing versus standard medical therapy (SMT) treat patients across different definitions etiologies. Pooled risk ratios were determined by...
Spirometry evaluates lung function by measuring airflow post-maximal inspiration, using parameters like FEV1, FVC, and the FEV1/FVC ratio for respiratory disease classification severity monitoring. Cough, inducing intrathoracic pressure changes, reflects pathology, impacting velocities cough sound properties. A correlation exists between spirometry values representing air flow-volume properties acoustic features of sounds. The present study explores sounds (FEV1, ratio) assessing health....
Cryptosporidium is a leading cause of moderate to severe childhood diarrhea in resource-poor settings. Understanding the natural history cryptosporidiosis and correlates protection are essential develop effective sustainable approaches disease control prevention.Children (N = 497) were recruited at birth semiurban slums Vellore, India, followed for 3 years with twice-weekly home visits. Stool samples collected every 2 weeks during diarrheal episodes tested species by polymerase chain...
Schizophrenia, a chronic psychiatric disorder, can affect one's productivity and psychosocial functioning. In Indian context, the responsibility of caring persons with schizophrenia is increasingly on their spouses. Spousal caregiver experience its relation disability in need to be studied.We conducted cross-sectional study among 52 outpatients spouses attending tertiary center. The objectives were: (a) explore spousal burden (b) assess between burden. adopted recommended ethical principles....
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) transmission in India 2020–2022 was driven predominantly by Wild (Wuhan‐Hu‐1 and D614G), Delta, Omicron variants. The aim of this study to examine the effect infections on humoral immune response cross‐reactivity spike proteins Wuhan‐Hu‐1, C.1.2., Omicron. Residual archival sera ( N = 81) received between January 2020 March 2022 were included. Infection status inferred a positive SARS‐CoV‐2 RT‐PCR and/or serology (anti‐N...
Abstract Introduction/Aims In Guillain–Barré syndrome (GBS), the sensitivity and specificity of phrenic compound muscle action potential (CMAP) measurements to predict endotracheal mechanical ventilation are unknown. Hence, we sought estimate specificity. Methods We performed a 10‐year retrospective analysis adult GBS patients from our single‐center laboratory database (2009 2019). The nerve amplitudes latencies before were recorded along with other clinical demographic features. Receiver...
Birth weight centile curves are commonly used as a screening tool and to assess the position of newborn on given reference distribution. twins known be less than those comparable singletons twin-specific birth recommended for use. In this study, we aim construct gestational age specific born in south India. The study was conducted at Christian Medical College, Vellore, records all consecutive pregnancies resulting twin births between 1991 2005 were reviewed. Only live 24 42 weeks gestation...
Introduction South Asians have high rates of cardiovascular disease (CVD) and its risk factors (hypertension, diabetes, dyslipidaemia central obesity). Left ventricular (LV) hypertrophy dysfunction are features these disorders important predictors CVD mortality. Lower birth infant weight greater childhood gain associated with increased adult mortality, but there few data on their relationship to LV function. The IndEcho study will examine associations size, growth during infancy, adolescence...
Abstract Purpose Identifying persistent bacteremia early in patients with neutropenia may improve outcome. This study evaluated the role of follow-up blood cultures (FUBC) positivity predicting outcomes among and carbapenem-resistant gram-negative bloodstream infections (CRGNBSI). Methods retrospective cohort conducted between December 2017 April 2022 included more than 15 years old CRGNBSI, who survived for ≥ 48 h, receiving appropriate antibiotic therapy had FUBCs. Patients polymicrobial...
This study examined the relative proportion of enteric pathogens associated with severe gastroenteritis (GE) among children younger than 2 years in a phase III efficacy trial ROTASIIL® vaccine India, evaluated impact co-infections on (VE), and characterized association between specific clinical profile GE. Stored stool samples collected from cases GE were tested by quantitative polymerase chain reaction using TaqMan™ Array Cards. Etiology was attributed calculating adjusted attributable...
Lack of robust data on economic burden due to enteric fever in India has made decision making typhoid vaccination a challenge. Surveillance for Enteric Fever network was established address gaps disease and burden.
Abstract Background Longitudinal studies are important to understand patterns of growth in children and limited India. It is identify an approach for characterising trajectories distinguish between who have healthy those poor. Many statistical approaches available assess the longitudinal data which difficult recognize pattern. In this research study, we employed functional principal component analysis (FPCA) as a method find pattern data. The purpose study describe child trajectory under 3...