A5021932448- Electronic Health Records Systems
- Mobile Health and mHealth Applications
- Digital Mental Health Interventions
- Biomedical Text Mining and Ontologies
- Tuberculosis Research and Epidemiology
- Cancer-related gene regulation
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- Ethics in Clinical Research
- RNA modifications and cancer
- Machine Learning in Healthcare
- Context-Aware Activity Recognition Systems
- Obstructive Sleep Apnea Research
- Cancer-related molecular mechanisms research
- Genomics and Rare Diseases
- Artificial Intelligence in Healthcare
- Peptidase Inhibition and Analysis
- Epigenetics and DNA Methylation
- Shoulder Injury and Treatment
- Health and Wellbeing Research
- Pneumonia and Respiratory Infections
- Healthcare Systems and Technology
- Dysphagia Assessment and Management
- Patient Dignity and Privacy
- Diagnosis and treatment of tuberculosis
Beth Israel Deaconess Medical Center
2018-2023
Boramae Medical Center
2015-2023
Harvard University
2022-2023
Seoul National University Bundang Hospital
2015-2020
Seoul Metropolitan Government
2015-2020
Seoul National University
2015-2020
Kangwon National University
2017
Korea International Cooperation Agency
2017
National University College
2015
New Generation University College
2015
Personal health record (PHR)-based care management systems can improve patient engagement and data-driven medical diagnosis in a clinical setting.
Background: Although using the technologies for a variety of chronic health conditions such as personal record (PHR) is reported to be acceptable and useful, there lack evidence on associations between use change outcome patients' response digital app. Objective: This study aimed examine impact PHR wearables improvement sustained app that can associated with patient engagement. Methods: We developed an Android-based mobile phone used wristband-type activity tracker (Samsung Charm) collect...
Due to the prevalence of personal health tracking, cases self-logged data being utilized in clinic are gradually increasing. However, obstacles clinicians' ability further adopt such data-driven medical consultations existing workflow remain, as lack time and poor interoperability. In this paper, we conducted a workshop design clinician interface supporting integration consultation into investigate role situ. After implementing designed based on results, observed 32 actual use within...
To design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and usability.We analyzed the architecture requirements of an HSP, including interface, business services, SaaS, quality attributes, privacy security, multi-lingual capacity. For cloud-based SaaS we focused on Clinical Decision Service (CDS) content basic functional mobile services. Microsoft's Azure computing...
Histone modifications play crucial roles in transcriptional activation, and aberrant epigenetic changes are associated with oncogenesis. Lysine (K) acetyltransferases 5 (TIP60, also known as KAT5) is reportedly implicated cancer development maintenance, although its function lung remains controversial. Here we demonstrate that TIP60 knockdown non-small cell lines decreased tumor growth, migration, invasion. Furthermore, analysis of a mouse model lung-specific conditional Tip60 knockout...
Rationale: We previously showed that the choice of levofloxacin or moxifloxacin for treatment patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (MDR-TB) did not affect sputum culture conversion at 3 months treatment.Objectives: To compare final outcomes between MDR-TB randomized to moxifloxacin.Methods: A total 151 participants who were included analysis in our previous trial followed through end treatment. Treatment compared 77 group and 74 group, based on 2008 World...
Prevention and management of chronic diseases are the main goals national health maintenance programs. Previously widely used screening tools, such as Health Risk Appraisal, restricted in their achievement this goal due to limitations, static characteristics, accessibility, generalizability. Hypertension is one most important requiring via nationwide program, care providers should inform patients about risks a complication caused by hypertension.Our was develop compare machine learning...
Objectives We aimed to develop a common health information exchange (HIE) platform that can provide integrated services for implementing the HIE infrastructure in addition guidelines participating an network South Korea. Methods By exploiting Health Level 7 (HL7) Clinical Document Architecture (CDA) and Integrating Healthcare Enterprise (IHE) Cross-enterprise Sharing-b (XDS.b) profile, we defined architectural model, exchanging data items their standardization, messaging standards, privacy...
Trans-Scirpusin A (TSA) is a resveratrol oligomer found in Borassus flabellifer L. We that TSA inhibited the growth of colorectal cancer Her2/CT26 cells vivo mice. Although some cytotoxic T lymphocytes (CTLs) were induced against tumor-associated antigen Her2, treatment did not significantly increase level Her2-specific CTL response compared to with vehicle treatment. However, there was significant TNF-α mRNA tumor tissue and Ab (antibody) production. More importantly, we overcomes...
To implement standardized machine-processable clinical sequencing reports in an electronic health record (EHR) system, the International Organization for Standardization Technical Specification (ISO/TS) 20428 international standard was proposed a structured template. However, there are no implementation guidelines data items from at site and or references implementing gene results use. This is significant challenge application of these standards individual sites.
To investigate the short-term effects of a lifestyle modification intervention based on mobile application (app) linked to hospital electronic medical record (EMR) system weight reduction and obstructive sleep apnea (OSA).We prospectively enrolled adults (aged >20 years) with witnessed snoring or from clinic. The patients were randomized into app user (n=24) control (n=23) groups. was designed collect daily data by wearing wrist activity tracker reporting dietary intake. A summary displayed...
<b>Background:</b> Although chronic obstructive pulmonary disease (COPD) is closely associated with gastroesophageal reflux (GERD), clinical significance of laryngopharyngeal (LPR) not yet elucidated in COPD. <b>Methods:</b> Prospective cohort was established among the 118 patients COPD from March 2013 to July 2014. Thirty two age- and sex-matched normal controls, who had routine health check-up during study period were included. Laryngopharyngeal finding score (RFS) symptom index (RSI) for...
Linezolid, an oxazolidinone, substantially improves treatment outcomes of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. We started a trial to test whether the use linezolid instead ethambutol could increase rate sputum culture conversion as 8 weeks in patients with drug-susceptible tuberculosis.This is phase II, multicenter, randomized study three arms. are enrolling pulmonary without rifampicin resistance screened by Xpert MTB/RIF® assay. The standard arm...
The demand for hospice has been increasing among patients with cancer. This study examined the current referral scenario terminally ill cancer and created a data form to collect information modified health exchange (HIE) more efficient system patients.Surveys were conducted asking detailed such as medical instruments patient admission policies of hospices, interviews held examine flow any additional requirements. A task force team was organized analyze results surveys.Six hospices completed...
최근 헬스케어 분야에서 지속적인 건강 관리 서비스를 제공하기 위해 챗봇 에이전트를 도입하는 시도가 늘어나고 있다. 하지만 아직까지 에이전트 설계에 대한 연구는 인간과 기계라는 구분에 머물러 있어, 에이전트에 신뢰, 친밀감, 행동 변화를 모두 고려해야 하는 영역에서의 활용하기에는 한계가 따라서 본 연구에서는 구분에서 나아가, 보다 다양한 정체성에 따라 사용자의 인식과 행동이 달라지는지 조사하고자 했다. 이를 정체성을 다르게 설정한 3개의 에이전트인 의사(개인), 병원(기관), 가상 에이전트(기계)를 제작한 후, 집단 간 설계(between-group design) 방식으로 36명의 사용자를 세 그룹으로 나누어 6일간 챗봇을 사용하며 습관을 기록하도록 하였다. 6일간의 사용을 마친 사후 설문 및 인터뷰를 통하여 사용자들의 개선에 어떤 영향이 있었는지 살펴보았다. 그 결과 의사와 병원 에이전트는 건강지키미 에이전트보다 높은 신뢰를 보였으며, 친밀감에 있어서도 더욱 평가를 받았다....
<sec> <title>BACKGROUND</title> Personal health record (PHR)–based care management systems can improve patient engagement and data-driven medical diagnosis in a clinical setting. </sec> <title>OBJECTIVE</title> The purpose of this study was (1) to demonstrate the development an electronic (EHR)–tethered PHR app named MyHealthKeeper, which retrieve data from wearable device deliver these hospital EHR system, (2) effectiveness intervention with trial results. <title>METHODS</title> To...
<sec> <title>BACKGROUND</title> Although using the technologies for a variety of chronic health conditions such as personal record (PHR) is reported to be acceptable and useful, there lack evidence on associations between use change outcome patients’ response digital app. </sec> <title>OBJECTIVE</title> This study aimed examine impact PHR wearables improvement sustained app that can associated with patient engagement. <title>METHODS</title> We developed an Android-based mobile phone used...
Abstract Background: Diabetes mellitus (DM) is a well-known risk factor for tuberculosis (TB). Metformin, which an essential anti-diabetic drug, has been shown to exhibit anti-TB effects in patients with DM. Its effect on preventing the development of TB among who are newly diagnosed DM remains unclear. We evaluated protective metformin type 2 . Methods: This was retrospective cohort study using claims database. The population included between January 2003 and March 2011. A user defined if...
Background The Korea Organ Donation Agency (KODA) provides various bereavement support programs to donor family. This study attempts evaluate the effectiveness of psychotherapy program by comparing average scores according application and suggest basis direction family care service in future. Methods According PHQ-9 scale intervention guideline as a selective which was applied group severely depressed subjects with score 15 or more. Thus, dividing participants into psychological treatment...
Abstract Epigenetic modifications in oncogenesis have long been an area of interest cancer research. Histone are crucial activities such as transcriptional activation, gene silencing, and epigenetic cellular memory. In particular, lysine acetylation via (K) acetyltransferases (KATs) implicated development. Interestingly, KAT5, also known Tip60, has reported to possess both tumor promoting suppressing properties depending on the context malignancy. Herein we report that KAT5 contributes...