A5080240254- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Laser-Plasma Interactions and Diagnostics
- Nuclear Physics and Applications
- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Radiation Effects and Dosimetry
- Radiation Dose and Imaging
- Laser-induced spectroscopy and plasma
- Particle Accelerators and Free-Electron Lasers
- Particle Detector Development and Performance
- High-pressure geophysics and materials
- Advanced X-ray and CT Imaging
- Lung Cancer Diagnosis and Treatment
- Particle accelerators and beam dynamics
- Digital Radiography and Breast Imaging
- Prostate Cancer Diagnosis and Treatment
- Atomic and Molecular Physics
- Photocathodes and Microchannel Plates
- Magnetic confinement fusion research
- Prostate Cancer Treatment and Research
- Advancements in Photolithography Techniques
- Urologic and reproductive health conditions
- Laser Design and Applications
- Ultrasound and Hyperthermia Applications
Agenzia Regionale Sanitaria della Puglia
2018
Istituto Nazionale di Fisica Nucleare
2007-2017
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud
2006-2017
University of Catania
2015-2016
Ospedale Cannizzaro
2004-2016
Istituto Nazionale di Fisica Nucleare, Sezione di Catania
2016
Institute of Molecular Bioimaging and Physiology
2014-2015
Fondazione Istituto G. Giglio di Cefalù
2011-2014
Accelerated proton beams have become increasingly common for treating cancer. The need cost and size reduction of particle accelerating machines has led to the pioneering investigation optical ion acceleration techniques based on laser-plasma interactions as a possible alternative. Laser-matter interaction can produce extremely pulsed bursts ultra-high dose rates (⩾ 109 Gy/s), largely exceeding those currently used in conventional therapy. Since biological effects ionizing radiation are...
Charged particle acceleration using ultra-intense and ultra-short laser pulses has gathered a strong interest in the scientific community it is now one of most attractive topics relativistic laser-plasma interaction research. Indeed, could represent future open new scenarios multidisciplinary fields, particular, medical applications. One biggest challenges consists using, perspective, high intensity laser-target to generate high-energy ions for therapeutic purposes, eventually replacing old...
When a carbon beam interacts with human tissues, many secondary fragments are produced into the tumor region and surrounding healthy tissues. Therefore, in hadrontherapy precise dose calculations require Monte Carlo tools equipped complex nuclear reaction models. To get realistic predictions, however, simulation codes must be validated against experimental results; wider dataset is, more models finely tuned.
<i>Objectives:</i> To evaluate the incidence of indolent prostate cancer (PCa; <0.5 ml and Gleason score, GS, ≤6) in men with microfocal PCa diagnosed on saturation biopsy (SPBx) submitted to radical retropubic prostatectomy. <i>Methods:</i> From January 2005 December 2008, 413 patients (median age 61.5 years) underwent SPBx 30 cores). A single neoplastic microfocus (5% or less a core) was found 55 all Median PSA equal 8.2 ng/ml, digital rectal examination negative...
Thomson Spectrometers (TPs) are widely used for beam diagnostic as they provide simultaneous information on charge over mass ratio, energy and momentum of detected ions. A new TP design has been realized at INFN-LNS within the LILIA (Laser Induced Light Ion Acceleration) ELIMED (MEDical application ELI-Beamlines) projects. This paper reports construction details its experimental tests performed PALS laboratory in Prague, with ASTERIX IV laser system. Reported data obtained polyethylene...
ELI-Beamlines is one of the four pillars ELI (Extreme Light Infrastructure) pan-European project. It will be an ultrahigh-intensity, high repetition-rate, femtosecond laser facility whose main goals are generation and applications high-brightness X-ray sources accelerated charged particles. In particular medical multidisciplinary with laser-accelerated beams treated by ELIMED task force, a collaboration between different research institutes. A crucial goal for this network represented design...
Radiochromic film (RCF) based multichannel diagnostics utilizes the concept of a stack detector comprised alternating layers RCFs and shielding aluminium layers. An algorithm on SRIM simulations is used to correct accumulated dose. Among standard information that can be obtained maximum ion energy some extend beam spectrum. The main area where this shines though geometrical characterization beam. Whereas other detectors such as Thomson parabola spectrometer or Faraday cups detect only...
Summary Radiotherapy techniques deliver ionizing radiations (X‐rays, photons, electrons, protons, etc.) inside cancerous tissues to kill the abnormal cells. Radiotherapy‐related activities such as optimization of therapeutic radiation dose patients, workers' radioprotection, linear accelerator commissioning, quality assurance processes and technical innovations accelerators are strongly based on ability predict distribution. Monte Carlo simulations so far most accurate tool for calculation...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation G. A. P. Cirrone, Cuttone, Candiano, M. Carpinelli, E. Leonora, D. Lo Presti, Musumarra, Pisciotta, L. Raffaele, N. Randazzo, F. Romano, Schillaci, V. Scuderi, Tramontana, R. Cirio, Marchetto, Sacchi, S. Giordanengo, Monaco; Absolute relative dosimetry for ELIMED. AIP Conf. Proc. 26 July 2013; 1546 (1): 70–80....
Nowadays, one of the biggest challenges consists in using high intensity laser-target interaction to generate high-energy ions for medical purposes, eventually replacing old paradigm acceleration characterized by huge and complex machines. In order investigate feasibility laser-driven ion beams multidisciplinary application, a dedicated beam transport line will be installed at ELI-Beamlines facility Prague (CZ), as part User-oriented ELIMAIA beam-line their potential applications. The...
Proton therapy is a precise form of radiation and thus it requires accurate quality control patients treatment. Protons may be more suitable than conventional X-rays for this task since the relative electron density distribution can measured directly with proton computed tomography (pCT). However, CT has its own limitation. The main limit that spatial resolution limited by multiple coulomb scattering inside body patient. In order to improve we need determine most likely path single body....
Laser accelerated proton beams represent nowadays an attractive alternative to the conventional ones and they have been proposed in different research fields. In particular, interest has focused possibility of replacing accelerating machines with laser-based accelerators order develop a new concept hadrontherapy facilities, which could result more compact less expensive. With this background ELIMED (ELIMED: ELI-Beamlines MEDical applications) project launched by LNS-INFN researchers...