A5101887011- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Knee injuries and reconstruction techniques
- Silk-based biomaterials and applications
- Hip disorders and treatments
- Anatomy and Medical Technology
- Bone Tissue Engineering Materials
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Additive Manufacturing and 3D Printing Technologies
- Lower Extremity Biomechanics and Pathologies
- Spinal Fractures and Fixation Techniques
- Metal and Thin Film Mechanics
- Medical Imaging and Analysis
- Reconstructive Surgery and Microvascular Techniques
- Dyeing and Modifying Textile Fibers
- Periodontal Regeneration and Treatments
- Spine and Intervertebral Disc Pathology
- Soft tissue tumor case studies
- Hereditary Neurological Disorders
- Fuzzy Systems and Optimization
- Musculoskeletal synovial abnormalities and treatments
- Optimization and Variational Analysis
Jining First People's Hospital
2024
Xian Yang Central Hospital
2024
Central Hospital of Zibo
2024
Mianyang Third People's Hospital
2024
Dalian Naval Academy
2024
Chinese PLA General Hospital
2024
Southwest Hospital
2009-2023
Army Medical University
2009-2023
Soochow University
2022
Zhongda Hospital Southeast University
2018-2021
Osteoarthritis (OA) is a chronic degenerative disease featured by cartilage erosion and inflammation. Luteolin, member of the flavonoid family, has been shown to exert anti-inflammatory antioxidative activities. However, potential biological effects underlying mechanism luteolin on chondrocytes OA progression remain largely elusive. In this study, effect were investigated in vitro vivo. Our data revealed that inhibited H2O2-induced cell death, apoptosis, oxidative stress, programmed...
The preferred treatment of intertrochanteric fractures in aged patients is controversial. purpose the present study was to evaluate outcomes Asian proximal femur intramedullary nail antirotation system (PFNA-II) for stabilization such fractures. PFNA-II used treat 163 elderly from March 2010 2013. comprised 69 men and 94 women with a mean age 74.7 ± 13.0 years. All were classified by Orthopaedic Trauma Association classification system; 53, 83, 27 as 31A1, 31A2, 31A3, respectively. We...
Pullulan hydrogels are widely used in tissue engineering and drug delivery. However, these do not meet the requirements of articular cartilage repair because their fast degradation rate poor mechanical strength. Herein, we fabricated a hybrid hydrogel system by combining pullulan with synthetic polymers polyethylene (glycol) diacrylate (PEGDA). In this study, was modified methacrylic anhydride (MA) to obtain photo-crosslinkable methacrylated (PulMA). Moreover, lithium...
To test the biomechanical properties of 3D printed tantalum and titanium porous scaffolds.Four types scaffolds with four alternative pore diameters, #1 (1000-700 μm), #2 (700-1000 #3 (500-800 #4 (800-500 were molded by selective laser melting technique, tested scanning electronic microscope, uniaxial-compression tests, Young's modulus tests; they compared same size pig femoral bone scaffolds.Under equivalent stress scaffold was 411 ± 1.43 MPa, which significantly larger than (P < 0.05). 2.61...
Abstract To compare percutaneous vertebroplasty (VP) and balloon kyphoplasty (BKP) for their effectiveness safety in the treatment of newly onset osteoporotic vertebral compression fractures (VCF). Patients with confirmed diagnosis VCF treated our center between January 2008 December 2016 were retrospectively included study. divided into 2 groups according surgical they have received. They followed 12 months after surgery by outpatient visits phone interviews. Changes VAS ODI scores,...
Recent studies highlight the vital role of oxidative stress and reactive oxygen species (ROS) during progression osteoarthritis (OA). Attenuating reducing generation in joints represent reasonable strategies for treatment osteoarthritis. To address potential question clinical translation, improve biocompatibility long-term performance current antioxidants, present study provided high biocompatible small positively charged tantalum nanoparticles (Ta-NH2 NPs) with sustained intra-articular...
Background Three-dimensional (3D) reconstruction has been used for various diseases, but few reports have described its application in pelvic after removal of giant chondrosarcoma. Case describing the clinical personalized 3D-printed titanium implants are needed future reference. presentation: We herein describe a 29-year-old woman with chondrosarcoma treated 3D implant. The surgery was successful, and patient recovered significant pain relief good functional recovery surgery. No...
Chronic inflammation and bone defects after total knee arthroplasty are a challenge for the orthopedic surgeon. There have been few reports on application of three-dimensional (3D) printed porous tantalum prosthesis in such situations. We report an 83-year-old female patient who presented to our clinic with consistent pain left 10 years severe decline mobility 2 years. inflammation, loosening tibial defect, osteoporosis were diagnosed. The was treated computer designed manufactured,...
Polymeric stent is a temporary cardiovascular scaffold, made of biodegradable poly (l-lactic) acid, to treat coronary artery stenosis, with expected resorption by the human body over two three years. In this paper, mechanical properties polymeric two-year in vitro degradation were studied and characterised using atomic force microscopy nanoindentation techniques, complemented analyses weight loss, gel permeation chromatography differential scanning calorimetry. Atomic assessed at surface,...
Robotic-assisted thoracoscopic surgery (RATS) and video-assisted (VATS) are new modes for the surgical treatment of mediastinal tumors. The differences in perioperative efficacy safety among RATS, VATS, conventional open (COS) a major concern surgeons. Most previous studies have not paid sufficient attention to roof This study comprehensively analyzed COS
Therapeutic effect of autologous concentrated growth factor on lower-extremity chronic refractory wounds: A case report
Background: Inappropriate posterior tibial loading and initial graft tension during anterior cruciate ligament (ACL) reconstruction may cause altered patellofemoral joint (PFJ) contact mechanics, potentially resulting in pain degeneration. Hypothesis: PFJ pressure would increase with the increases ACL reconstruction. Study Design: Controlled laboratory study. Methods: Nine fresh-frozen, nonpaired human cadaveric knees were tested a customized jig from 0° to 120° of knee flexion. First, was...
Abstract Radiographs are widely used to measure distal femoral valgus cut angle (VCA) in total knee arthroplasty (TKA), but its accuracy is controversial. This study three-dimensional (3D) reconstruction models verify the of VCA measurements on radiographs, and explore correlation with hip–knee–ankle (HKA) lateral bowing (FBA). A 444 osteoarthritis knees patients from August 2016 June 2018 was included retrospectively. On two-dimensional (VCA-2D) measured between mechanical axis anatomical...
The present study aimed to investigate the expression of a neuropeptide symptomatic mediopatellar plica (MP) prove that there was significant correlation between substance-P (SP) in MP and patellofemoral pain. specimens synovial were obtained by knee arthroscopy. Semi-quantitative analysis used SP, compared innervation density SP among three groups: Blank control (asymptomatic plica), positive (symptomatic with other injuries) experimental without groups paired t-test, one-way variance...
Guillain-Barré syndrome (GBS) is a worldwide demyelinating polyradiculopathy and polyneuropathy. Currently, there no specific drug for GBS, established treatment generally based on immune-modulating with plasma exchange or intravenous immunoglobulin in combination supportive care. This study aimed to investigate the efficiency of integrated Chinese Western medicine acute GBS treatment.We enrolled 73 subjects, randomly divided them into two groups: 35 cases traditional (TCM) group, 28 Control...