- Platelet Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 Clinical Research Studies
- Mobile Crowdsensing and Crowdsourcing
- Long-Term Effects of COVID-19
- Stroke Rehabilitation and Recovery
- Privacy-Preserving Technologies in Data
- Internet Traffic Analysis and Secure E-voting
- Prosthetics and Rehabilitation Robotics
- Health Systems, Economic Evaluations, Quality of Life
- Sleep and Work-Related Fatigue
- Heparin-Induced Thrombocytopenia and Thrombosis
- Mast cells and histamine
- Adenosine and Purinergic Signaling
- Genetic Neurodegenerative Diseases
- Biochemical and Structural Characterization
- Atherosclerosis and Cardiovascular Diseases
- Electrolyte and hormonal disorders
- Central Venous Catheters and Hemodialysis
- PI3K/AKT/mTOR signaling in cancer
- Muscle and Compartmental Disorders
- SARS-CoV-2 and COVID-19 Research
- Amyotrophic Lateral Sclerosis Research
- Pancreatitis Pathology and Treatment
- Diverse Perspectives in Modern Studies
Guangzhou Railway Polytechnic
2024
Shanghai Jiao Tong University
2007-2023
Renji Hospital
2022
Peking University
2021
Weatherford College
2021
Hunan Normal University
2021
ORCID
2021
Guangzhou University of Chinese Medicine
2021
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2021
Shanghai Sixth People's Hospital
2018
The involvement of platelets in tumor progression is well recognized. depletion circulating or pharmacologic inhibitors platelet activation decreases the metastatic potential cells metastasis mouse models. ADP receptor P2Y12 amplifies initial hemostatic responses activated by a variety agonists and stabilizes aggregation, playing crucial role granule secretion, integrin thrombus formation. However, relationship between not clear. In our study, Lewis Lung Carcinoma (LLC) spontaneous model was...
The aim of the study was to evaluate role purinergic receptor P2Y, G protein-coupled 12 (P2Y12), an ADP receptor, in development atherosclerotic lesions.Apolipoprotein E-null mice were crossed with P2y12(-/-) generate double knockout mice. and control apolipoprotein fed a high-fat diet for 20 weeks. Assessment lesions demonstrated that P2Y12 deficiency caused diminished lesion area, increased fibrous content at plaque site, decreased monocyte/macrophage infiltration lesions. Polymerase chain...
Integrin αIIbβ3 mediated bidirectional signaling plays a critical role in thrombosis and haemostasis. Signaling by the β3 subunit has been extensively studied, but αIIb not characterized. Previously, we reported that platelet granule secretion TxA2 production induced outside-in is negatively regulated cytoplasmic domain residues R724KEFAKFEEER734. In this study, identified part of pathway utilized signaling. Platelets from humans gene deficient mice, genetically modified CHO cells as well...
Background: Gastrointestinal cancers account for 20% of all deaths worldwide.Gastric cancer (GC) patients are susceptible to psychological change, especially depression which is commonly induced by chronic stress.Gastric precancerous lesions (GPL) an important prodromal stage in the occurrence gastric cancer.Chronic stress influences prognosis GC and may influence process GPL as well.Methods: Sixty SD rats were randomly divided into a control group, GPL+CUMS group.In 200μg/mL...
Federated learning (FL) has emerged as an effective solution to decentralized and privacy-preserving machine for mobile clients. While traditional FL demonstrated its superiority, it ignores the non-iid (independently identically distributed) situation, which widely exists in scenarios. Failing handle situations could cause problems such performance decreasing possible attacks. Previous studies focus on "symptoms" directly, they try improve accuracy or detect attacks by adding extra steps...
Abstract Objective . Snoring is the most typical symptom of obstructive sleep apnea hypopnea syndrome (OSAHS) that can be used to develop a non-invasive approach for automatically detecting OSAHS patients. Approach In this work, model based on transfer learning and fusion was applied classify simple snorers Three kinds basic models were constructed pretrained Visual Geometry Group-16 (VGG16), audio neural networks (PANN), Mel-frequency cepstral coefficient (MFCC). The XGBoost select features...
Abstract For mammalian organism, fertilization begins with species‐specific recognition between sperm and egg, a process depending upon egg zona pellucida glycoproteins putative interacting protein(s). In mouse, glycoprotein ZP3 is believed to be the primary receptor for inducer of acrosomal reaction, its function has been attributed specific O‐linked oligosaccharides attached polypeptide backbone. While lots reports have focused on role ZP3's in fertilization, there are few concerning To...
The energy Internet (EI) equipment may face threats that attackers poison federated learning (FL) models to disturb electricity load forecasting. To mitigate this vulnerability, it is important study forecasting disturbance approaches. This article proposes a side-channel analysis (SCA)-based approach. First, we design an FL SCA scheme extract power information from the chip running model. Second, propose data speculation method using optimized convolutional neural network trained with...
Recent evidence suggests that automated peritoneal dialysis (APD) might be a feasible alternative to hemodialysis (HD) in urgent-start dialysis.This prospective study enrolled end-stage renal disease (ESRD) patients who had started APD as an modality at single center. Dialysis-related complications were recorded. Dialysis adequacy and electrolytes imbalance compared between baseline, 14 42 days after catheter insertion. Technique survival patient also recorded.A total of 36 included the...
Technological evolution has brought great changes to traditional industries.Nowadays farmers obtain benefits such as intelligent production and convenient management from agriculture.Nevertheless, there still exists many flaws in current solutions.Deficiencies energy management, data transmission privacy preservation are supposed be solved.In this paper, the preserved cyberphysical searching framework is proposed tackle these problems.This four-layer can provide a way for manage by simply...
Although the research on risk factors of anterior communicating artery (AComA) aneurysm has made great progress, independent effect each factor rupture AComA is controversial among different studies. We will perform a protocol for systematic review and meta-analysis to investigate quantify their effects.A search according Preferred Reporting Items Systematic Reviews Meta-Analysis Protocols guidelines in PubMed, Embase, Cochrane Library databases was conducted from inception August 31, 2021...
AbstractBACKGROUND:Spinocerebellar ataxia is a inherited neurodegenerative disease with progressive cerebellar masonic movement disorders as the main clinical manifestation. So far, no drug available to control progression.OBJECTIVE:To observe effect of umbilical cord mes
The experimental studies and clinical trials for a large number of stroke patients have indicated that active again on brain damage after training can restore the restructuring function to improve motor efficiently. skeleton post-stroke rehabilitation robot standardization treatment carried out by these robots help recover great extent social life quality life. Due high-frequency disturbances fast velocity, dynamic characteristics platform change constantly, leading time-varying nonlinear...
The application of skeleton post-stroke rehabilitation robot and the standardization treatment after acute phase can help patients recover in terms improving brain function restructuring motor function, thus increasing patients' life quality. However, controller design task is deemed challenging due to physical limitations actuator (especially wrist joint) patient's safety issues. nonlinear factors such as input magnitude, rate output saturation need be taken into account at very beginning...
MicroRNAs (miRNAs) are endogenous 22-nt RNA species that play important regulatory roles in animals and plants by cleavage or translational repression of their targeted mRNAs. Advances the understanding miRNA biogenesis, target recognition participation networks demonstrate a role for miRNAs lineage decisions progenitor cells organogenesis. Since spermatogenesis is paradigm development provides great model studying cell differentiation cell- decision, it interest to characterize involved...
Scientific and Clinical Abstracts From the 36th Annual Wound, Ostomy Continence Conference: Tampa, Florida: June 5–9, 2004: Research Abstracts: Category—Continence
Background: Coronavirus disease 2019 (COVID-19) causes significant mortality during the pandemic in recent years. Paxlovid, an HIV-1 protease and CYP3A inhibitor, reduces hospitalization rate patients infected with Omicron variant of SARS-CoV-2. However, data regarding effectiveness Paxlovid treating COVID-19 kidney injury are limited.Methods: The clinical were collected from Renji Hospital, Shanghai Jiao Tong University, School Medicine, Shanghai, China between April 7, 2022, June 21, 2022....