Haining Luo

ORCID: 0000-0003-2409-3355
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Prenatal Screening and Diagnostics
  • Effects and risks of endocrine disrupting chemicals
  • Reproductive Health and Technologies
  • Reproductive System and Pregnancy
  • Genomic variations and chromosomal abnormalities
  • Genetic Syndromes and Imprinting
  • Ectopic Pregnancy Diagnosis and Management
  • Air Quality and Health Impacts
  • Pluripotent Stem Cells Research
  • Toxic Organic Pollutants Impact
  • Endometriosis Research and Treatment
  • Renal and related cancers
  • Uterine Myomas and Treatments
  • Reproductive Physiology in Livestock
  • CRISPR and Genetic Engineering
  • Maternal and Perinatal Health Interventions
  • Pregnancy and preeclampsia studies
  • COVID-19 Impact on Reproduction
  • Sperm and Testicular Function
  • Climate Change and Health Impacts
  • Reproductive Health and Contraception
  • Gynecological conditions and treatments

Tianjin Central Hospital of Gynecology Obstetrics
2016-2025

The Central Hospital of Xiao gan
2025

Nankai University
2022-2024

Shandong First Medical University
2024

Shandong Tumor Hospital
2024

Tianjin Medical University
2021

Huazhong University of Science and Technology
2007-2010

Tongji Hospital
2010

The human exposome remains limited due to the challenging analytical strategies used reveal low-level endocrine-disrupting chemicals (EDCs) and their metabolites in serum urine. This limits integrity of EDC exposure assessment hinders understanding cumulative health effects. In this study, we propose an enhanced protocol based on multi-solid-phase extraction (multi-SPE) expand with polar EDCs train a machine learning (ML) model for methodology prediction molecular descriptors. measurement 70...

10.1021/acs.est.4c09522 article EN Environmental Science & Technology 2025-02-10

Anastomotic leak (AL) is a common complication in patients with operable esophageal squamous cell carcinoma (ESCC) treated neoadjuvant chemoradiotherapy (NCRT) and radical esophagectomy. Therefore, this study aimed to establish validate nomogram predict the occurrence of AL. Between March 2016 December 2022, ESCC undergoing NCRT esophagectomy were retrospectively collected China. Clinicopathologic radiomics characteristics included univariate logistic regression analysis, statistically...

10.1186/s12885-025-13884-9 article EN cc-by-nc-nd BMC Cancer 2025-03-15

Caesarean section rates are rising worldwide. One adverse effect of caesarean reported in some studies is an increased risk subfertility. Only a few have assessed the relationship between previous mode delivery and vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) reproductive outcomes. In this study, we primarily investigated impact history with or without defects on IVF/ICSI-ET outcomes compared to vaginal history.This retrospective study included 834 women...

10.1186/s12884-021-03955-7 article EN cc-by BMC Pregnancy and Childbirth 2021-07-06

Volatile organic compounds (VOCs) are ubiquitous environmental pollutants and have been implicated in adverse health outcomes. In this study, concentrations of 11 VOC metabolites (mVOCs) three oxidative stress biomarkers (8-oxo-7,8-dihydro-2′-deoxyguanosine, 8-oxo-7,8-dihydro-guanosine, dityrosine) were determined 205 urine samples collected from 12 cities across mainland China. Urinary ∑11mVOC ranged 498 to 1660 ng/mL, with a geometric mean (GM) value 1070 ng/mL. The factorial analysis...

10.1021/acs.est.3c06055 article EN Environmental Science & Technology 2023-11-30

Abstract Background Due to various iatrogenic and social factors, the global caesarean delivery (CD) rate has risen sharply in past 30 years. It is more complicated dangerous for women with a scarred uterus experience pregnancy again than previous vaginal (VD). In this study we investigated impact of scar defects (CSDs) on outcomes after vitro fertilization frozen-thawed embryo transfer (IVF-FET). Methods We conducted retrospective cohort that included 1122 aged < 40 years who had history...

10.1186/s12884-022-05085-0 article EN cc-by BMC Pregnancy and Childbirth 2022-10-13

Anti-Müllerian hormone (AMH) is used as a biomarker to estimate ovarian reserve. The relationship between AMH and early miscarriage of in vitro fertilization (IVF) still inconclusive. This study aimed explore whether serum levels are associated with rates after fertilization/intracytoplasmic sperm injection (IVF/ICSI) fresh embryo transfer (ET).

10.1186/s12884-022-04591-5 article EN cc-by BMC Pregnancy and Childbirth 2022-04-02

The adverse effect of ambient PM2.5 exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort 141,040 cycles to evaluate the VEP using in vitro fertilization and embryo transfer platform high-resolution data China. first investigated association between 1 week before after date VEP. average concentrations 2 weeks were approximately 47 μg/m3. pooled results revealed...

10.1021/envhealth.4c00107 article EN cc-by-nc-nd Environment & Health 2024-10-21

Type 3 fibroids are a special subtype of intramural that likely to affect the pregnancy outcomes assisted reproductive techniques. Hysteroscopic resection is treatment for type fibroids, but there has few study its efficacy date. In this we evaluated effect hysteroscopic on in infertile women.This retrospective case-control was conducted from January 1, 2014 June 30, 2021. Patients who underwent IVF-ICSI our unit were divided into fibroid group and myomectomy group. The inclusion criteria as...

10.1186/s12884-022-04828-3 article EN cc-by BMC Pregnancy and Childbirth 2022-06-28

Although periconception vaccination is important to maternal and neonatal health, little known about the COVID-19 vaccine hesitancy among infertile couples seeking fertility treatment. Thus, we conducted this survey patients in a reproductive medicine center, between September 2021 December 2021, estimate prevalence of its influencing factors. Information was collected through face-to-face interviews volunteers. Among 987 included interviewees, 17.33% reported primary vaccination, 25.63%...

10.3389/fimmu.2022.973600 article EN cc-by Frontiers in Immunology 2022-09-27

Phthalates (PAEs) are widely used plasticizers drawing increasing concern due to reproductive toxicity. However, studies on serum PAEs metabolites (mPAEs) and their associations with human ovarian function remain very scarce. In this study, from April 2019 August 2020, a total of 297 women childbearing age were recruited in Tianjin, China. Eleven mPAEs analyzed samples eight detected at frequencies > 65% median concentrations 0.43-15.3 ng/mL. multinomial logistic analysis, an increase mono...

10.1016/j.ecoenv.2022.113909 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2022-08-08

This retrospective cohort study aimed to analyse the risk of congenital anomalies (CAs) in infants conceived by infertile women through assisted reproductive technology (ART). A total 9,013 clinical pregnancy cycles resulting 9,101 live births between 2004 and 2014 were analysed. Congenital evaluated compared with spontaneous pregnancies women. born following ART. Three subgroups established: In vitro fertilisation fresh embryo transfer (IVF-ET), n=2,919, intracytoplasmic sperm injection...

10.3892/etm.2018.6572 article EN Experimental and Therapeutic Medicine 2018-08-03

To investigate the follicle microenvironment of individuals with premature ovarian insufficiency (POI), normal reserve (normal) and advanced maternal age (AMA), identify potential therapeutic targets.

10.1093/biolre/ioae157 article EN cc-by Biology of Reproduction 2024-11-08
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