Acute venous thrombosis is prevalent and potentially fatal. Accurate diagnosis of early thrombus needed for patients in timely clinical intervention to prevent life-threatening conditions. Photoacoustic imaging (PAI) with excellent spatial resolution high optical contrast shows more promise this purpose. However, its application dramatically limited by signal-off effect on because the ischemia which lacks endogenous photoacoustic (PA) signal hemoglobin. To address dilemma, we herein report...

This meta-analysis was performed to evaluate the efficiency and safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment November 2012. Studies on implants metal ankle fractures selected. The using RevMan 5.1. Ten studies with 762 patients included analyzed. Compared implants, used internal fixation produce similar radiographic...

BACKGROUND:Chronic osteomyelitis is one of the currently refractory diseases. The aim this study to discuss method and curative effects vacuum sealing drainage (VSD) treatment combined with skin flap transplantation antibiotic bone cement for chronic tibia osteomyelitis. MATERIAL AND METHODS:For study, 18 cases open fracture secondary were selected. After granulation tissue wound surface became fresh infection was controlled, repaired a medial head gastrocnemius transfer or myofascial...

Gustilo-Anderson type III traumas have been described as high-energy injuries with severe bone defects and extensive soft tissue damage, which remain a challenging entity, due to an inherent risk of infection, nonunion even amputation. The emergency management such trauma presents additional difficulties. Our study attempts retrospectively evaluate the Masquelet technique combined muscle flap for Gustilo lower limb segmental loss in emergencies assess key points success this technique. From...

Objective: NIR-II imaging with indocyanine green (ICG) has been clinically used in liver tumor resection.However, few data are available concerning the application of ICG-NIR-II lymphatic and vascular systems clinic.To expand promote clinical translation this approach, we aimed to investigate feasibility for monitoring both physiological pathological conditions using a swine model compared it ICG-NIR-I imaging.Methods: constructed portable system suitable large animals.Different simulated...

Abstract The wide application of image classification has given rise to many intelligent systems, such as face recognition which makes our life more convenient. However, the ensuing privacy leakage problem become increasingly serious. training a deep neural network requires lots data, may contain sensitive information users and be exploited by data collectors. A perturbation algorithm named RRN is proposed for based on local differential privacy, provides rigorous guarantee. Existing...

Nanoparticles were produced by encapsulating CdS quantum dots (QDs) with quaternized chitosan (N-(2- hydroxyl) propyl-3-trimethyl ammonium chloride, HTCC), in order to improve general biocompatibility and stability of pure QDs. The properties QDs encapsulated HTCC nanoparticles (HTCC/CdS QDs) can be controlled changing the mass ratios QD (16:1, 8:1, 4:1, 2:1, 1:1, 1:2, 1:4, 1:8). Characterizations HTCC/CdS performed using ultraviolet-visible, fluorescence spectrometry, sizezeta analysis. As...

Previous studies have confirmed that adiponectin (APN) plays a protective role in myocardial ischaemia-reperfusion (IR) injury, and the aim of this study was to investigate its effect on skeletal muscle. ELISA used detect levels Creatinine Kinase (CK), LDH, SOD MDA plasma lower limbs mice, IL-6, IL-1β TNF-α gastrocnemius. Quantitative PCR expression level miR-21. TUNEL staining apoptosis The proteins, autophagy marker proteins downstream target genes miR-21 gastrocnemius were detected by...

Skin avulsion is commonly seen in individuals exposed to heavy shearing forces. Subcutaneous tissue detachment and bone fractures usually accompany skin avulsion. Thus, the estimation of extent damaged very important. Currently, viability subcutaneous determined by clinical observations, these observations always underestimate true avulsed skin. Herein, we synthesized an innovative probe, CH1055-GRRRDEVDK (CH1055-GK), which can specifically bind caspase-3 so as image define necrotic regions....

Hook plate fixation is the traditional method for treating distal clavicle fractures. However, in recent years, locked applications have emerged as a promising treatment method. This study aimed to compare short- and mid-term clinical efficacy of anatomical with coracoclavicular ligament augmentation using anchor nails that hook fractures.This was retrospective single-center cohort investigating patients fractures treated between January 2016 February 2019 Zhongnan Hospital Wuhan University....

Background and Objective The management of bone defects is still a difficult problem. Local vascularized grafts represent an efficient widely used method. In this retrospective report, iliac flaps the ascending branch lateral circumflex femoral artery were for proximal femur defects. Patients Methods hospital information system clinical data collected by surgeons retrospectively reviewed. with massive reconstructed included. Relevant data, including general information, perioperative...

Objective To design a kind of bioactive glasses/chitosan (BG/CS) composite materials,and investigate their physico-chemical properties and cell compatibility.Methods 2.0％ chitosan hydrochloric acid solution β-glycerophosphate on ice conditions in the 7∶1 ratio well mixed.after CS/BG become 2.0∶ 1.0,1.0∶ 1.0,1.0∶1.5 gelatinous liquid stage.Save it the-80 ℃ frige,formed by freeze-drying machine.After 20 kGy 60Go radiation sterilization get sample.By scanning electron microscope,X-ray...

Objective To evaluate the physicochemical properties and bicompatibility of carbon-nanotubes/hydroxypatite/chitosan scafflod for bone tissue engineering. Methods MWCNT/n-HA/CS scaffolds wre generated by solution blending freeze-drying technology. The morphology composition were analyzed scanning electron microscopy, X-ray diffraction Fourier transform infrared spectroscopy, after this, results which mixed CNTS in evaluated. effects on adherence proliferation rabbit marrow stroma cells...

As deep learning models have made remarkable strides in numerous fields, a variety of adversarial attack methods emerged to interfere with models. Adversarial examples apply minute perturbation the original image, which is inconceivable human but produces massive error model. Existing achieved good results when network structure known. However, case unknown structures, effectiveness attacks still needs be improved. Therefore, transfer-based are now very popular because their convenience and...

News recommendation system is designed to deal with massive news and provide personalized recommendations for users. Accurately capturing user preferences modeling users the key recommendation. In this paper, we propose a new framework, based on topic embedding knowledge (NRTK). NRTK handle titles that have clicked from two perspectives obtain representation :1) extracting explicit latent features mining users' them in historical behaviors; 2) entities propagating potential graph....

Objective To investigate the choice of methods and time on treatment Gustilo type 11I B m c open tibia fractures by bone fixation tissue flap repairing. Methods The clinic data 156 cases Ⅲ ⅢC were retrospectively studied. There 102 males 34 females, with average age years（range 14 to 68 years）. Ninety-eight classified as ⅢB 38 C in degree. In all cases, one hundred thirteen treated one- stage external fixation, ninteen secondary fixation. Sixty-seven wounds repaired one-stage vascular...

Objective To investigate the methods and therapeutic effects of repairing severe injury to lower leg at middle advanced stages. Methods Altogether 45 patients suffering from complications after were investigated. The infections controlled with vacuum sealing drainage; soft tissue defects, bone defects nonunion fracture treated microsurgery; large tibial repaired transfer; functions knee ankle joints improved arthrolysis arthroplasty. Results Forty-one followed up for 12 64 (average, 38)...

Objective To investigate the composite of chitosan(CS) and polyvinyl alcohol (PVA) as scaffold carrier for rabbit chondrocytes nurture growth.Methods The third passage were seeded in CS/PVA gel 24,48 72 h after which cytoactive toxicity determined by MTT respectively.After one,two three weeks,the growing status morphology observed with scaning electron microscope (SEM) laser confocal scanning fluorescence (LCSM).Results remained high proliferation ability.MTT measuring cell activity...

Objective To explore the effect of use flap transplantation combined with Masquelet tech- nique in repair long bone accompanied soft tissue defect. Methods The retrospective study includes 16 cases defects over 6.0 cm defect from March, 2013 to 2016, 13 males and 3 females, which ages range 65 years. The length ranged 12.0 cm, an average 8.5 while wound 5.2 cm×3.5 16.0 cm×7.5 cm. There were 8 out involve infection: Staphylococcus aureus (including 1 MRSA) , 2 epidermidis, Enterobacter...