A5030386782- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Retinopathy of Prematurity Studies
- Retinal Development and Disorders
- Cerebral Venous Sinus Thrombosis
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Intraoperative Neuromonitoring and Anesthetic Effects
- Optical Coherence Tomography Applications
- Hospital Admissions and Outcomes
- Corneal surgery and disorders
- Neonatal Respiratory Health Research
- Phosphodiesterase function and regulation
- Sleep and Work-Related Fatigue
- Neurosurgical Procedures and Complications
- Neonatal Health and Biochemistry
- Surgical Simulation and Training
- Nitric Oxide and Endothelin Effects
- Opioid Use Disorder Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Renin-Angiotensin System Studies
Kaiser Permanente Tysons Corner Medical Center
2023-2024
Johns Hopkins Medicine
2017-2022
Johns Hopkins University
2017-2022
Kaiser Permanente
2021-2022
National Eye Institute
2019-2020
Duke Medical Center
2016-2017
Duke University Hospital
2016-2017
Duke University
2016
Novartis (France)
2016
Pharmac
2016
We and others have reported mutations in the cardiac predominant sodium channel gene SCN5A patients with atrial fibrillation (AF). also that SCN1B is associated Brugada syndrome isolated conduction disease. tested hypothesis 4 beta-subunit genes SCN1B-SCN4B contribute to AF susceptibility.Screening for was performed 480 (118 lone 362 cardiovascular disease) 548 control subjects (188 ethnically defined anonymized 360 without AF). The effects of mutant beta-subunits on mediated currents were...
To evaluate the effect of vitrectomy on intraocular pressure (IOP).Retrospective cohort study. Medical records 101 eyes patients undergoing nonemergent were reviewed for rates open-angle glaucoma, increased IOP >4 mmHg from baseline, change in and cataract formation. Preoperative last measured IOPs recorded. Baseline risk characteristics including lens status diabetes analyzed. Main outcome measures 1) incidence glaucoma; 2) increase mmHg; 3) IOP.Mean follow-up was 49 months (range, 12-105...
Abstract: Fulminant idiopathic intracranial hypertension (FIIH) is a subtype of (IIH) characterized by rapid, severe, progressive vision loss. Surgical intervention often performed either as cerebrospinal fluid (CSF) shunt procedure or an optic nerve sheath fenestration or, at times, both. These surgical procedures carry significant risk morbidity and failure. We present 2 patients in whom temporary lumbar drain was successfully used the management medically undertreated pediatric FIIH,...
Objectives/Hypothesis To evaluate the trend and factors associated with surgical management of orbital cellulitis. Study Design Retrospective database study. Methods using State Inpatient Databases (SIDs) from 2008 to 2015. Patients an International Classification Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) diagnosis code for cellulitis were identified in SIDs following states: Arkansas, Florida, Iowa, Maryland, Nebraska, New York, Wisconsin. Surgery was defined as ICD‐9‐CM...
To evaluate novice and senior vitreoretinal surgeons after various exposures. Multiple comparisons ranked the importance of these exposures for surgical dexterity based on experience.
<h3>Importance</h3> Vitreoretinal surgery can be technically challenging and is limited by physiologic characteristics of the surgeon. Factors that improve accuracy precision vitreoretinal surgeon are invaluable to surgical performance. <h3>Objectives</h3> To establish weight-adjusted cutoffs for caffeine β-blocker (propranolol) intake determine their interactions in association with performance novice microsurgeons. <h3>Design, Settings, Participants</h3> This single-blind cross-sectional...
Purpose To describe a case of acute macular neuroretinopathy (AMN) in patient with recent COVID-19 vaccination and infection who demonstrated atypical features on presentation.Observations A 64-year-old woman presented central vision loss both eyes (OU). She had recently received the Moderna vaccine rapidly developed systemic symptoms. Testing revealed infection. Visual acuities were 20/200 OU near-infrared reflectance hypo-reflective lesions maculae OU, optical coherence tomography (OCT)...
To explore vitreoretinal pathologies and their longitudinal changes visible on handheld optical coherence tomography (OCT) of young children with familial exudative vitreoretinopathy.The authors retrospectively analyzed OCT images for interface retinal abnormalities optic nerve head (ONH) elevation.From 26 eyes 16 (mean age 32 months) vitreoretinopathy, 10 had ONH dragging photographs, in these, revealed temporal anterior displacement, prominent vitreopapillary adhesion or traction, fiber...
To evaluate the effect of previous vitrectomy on incidence macular oedema (MO) after cataract surgery in diabetic eyes.Ninety phakic eyes 70 patients with diabetes undergoing non-emergent were reviewed for rates postvitrectomy MO, formation and postcataract MO. Preoperative final best-corrected visual acuity recorded. Baseline risk characteristics analysed.Postvitrectomy MO increases initially but then levels off at 28% by 4 years. Cumulative proportion requiring climbs steadily, reaching...
Background/aims Fetal haemoglobin (HbF) has an oxyhaemoglobin dissociation curve that may affect systemic oxygenation and the development of retinopathy prematurity (ROP). The study aim is to characterise effects HbF levels on ROP development. Methods Prospective conducted from 1 September 2017 through 31 December 2018 at Johns Hopkins NICU. Preterm infants with measured birth, 31, 34 37 weeks post-menstrual age (PMA), complete blood gas SpO 2 recorded up 42 PMA, least one exam were...