Xiangwei Zhai

ORCID: 0000-0003-2967-5573
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Genetic factors in colorectal cancer
  • Liver Disease and Transplantation
  • Renal and related cancers
  • Single-cell and spatial transcriptomics
  • Genetics, Aging, and Longevity in Model Organisms
  • Pluripotent Stem Cells Research
  • Reproductive Biology and Fertility
  • Genomic variations and chromosomal abnormalities
  • Cancer Genomics and Diagnostics
  • Gene Regulatory Network Analysis
  • Advanced Fluorescence Microscopy Techniques
  • Neuroscience and Neural Engineering
  • Hepatitis Viruses Studies and Epidemiology
  • interferon and immune responses
  • RNA Interference and Gene Delivery
  • Alcohol Consumption and Health Effects
  • Robotics and Sensor-Based Localization
  • Immune Cell Function and Interaction
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Advanced Glycation End Products research
  • Advanced Image and Video Retrieval Techniques
  • Diet and metabolism studies

Sun Yat-sen University
2023-2024

Shandong Province Animal Husbandry and Veterinary Bureau
2024

Bioscience (China)
2023

Shenzhen Institutes of Advanced Technology
2023

Chinese Academy of Sciences
2023

University of Macau
2023

Xiamen University
2023

Stanford University
2023

Peking University
2019-2022

Zhengzhou University
2019-2020

Contrast-induced acute kidney injury (CIAKI) is a common and serious complication following contrast administration in patients undergoing percutaneous coronary intervention (PCI). dapagliflozin, sodium-glucose co-transporter 2 inhibitor (SGLT2i), has demonstrated renal protective effects various clinical settings. However, the impact of dapagliflozin on incidence CIAKI with type diabetes mellitus (T2DM) PCI not yet fully understood. To evaluate long-term prognosis T2DM PCI. This...

10.3389/fmed.2025.1552539 article EN cc-by Frontiers in Medicine 2025-03-05

Background and Objective: Parkinson disease (PD) with rapid eye movement (REM) sleep behavior disorder (PD-RBD) tend to be a distinct phenotype more severe clinical characteristics pathological lesion when compared PD without RBD (PD-nRBD). However, the mechanism underlying PD-RBD remains unclear. We aim use resting-state functional magnetic resonance imaging (rs-fMRI) explore of from perspective internal connectivity networks. Materials Methods: A total 92 patients 20 age sex matched normal...

10.3389/fneur.2020.563624 article EN cc-by Frontiers in Neurology 2020-10-27

This study was designed to explore if antiviral treatment influences the performance of serum alpha-fetoprotein (AFP) for hepatocellular carcinoma (HCC) among high-risk chronic HBV-infected patients. A total 5936 patients who had evidence HBV infection were enrolled from four independent centres in this retrospective study, including 1721 hepatitis B (CHB), 2286 liver cirrhosis (LC), 798 HCC within Milan criteria and 1131 beyond Stratified by whether they received or not, further divided...

10.1111/jvh.13388 article EN cc-by-nc Journal of Viral Hepatitis 2020-08-27

Visual SLAM (Simultaneous Location and Mapping) has gained popularity in the field of autonomous driving, virtual reality augmented recently. However, popular feature-based visual systems are usually sensitive to brightness translation. To make our system more robust, we present a real-time robust with low drift high precision. We contribute an image pre-processing module together CLAHE (Contrast Limited Adaptive Histogram Equalization) algorithm locally enhance contrast get feature details....

10.1109/cyberc.2019.00030 article EN 2019-10-01

As a hepatocellular carcinoma biomarker, serum Golgi protein 73 (GP73) is reportedly related to inflammation. Acute-on-chronic liver failure (ACLF) characterized by severe systemic In this study, we aimed explore the association between GP73 level and short-term mortality in patients with alcohol-associated disease-related ACLF (ALD-ACLF).This retrospective cohort study involved 126 Chinese adults ALD-ACLF. Baseline was measured using enzyme-linked immunosorbent assay. Patients were...

10.14218/jcth.2020.00133 article EN Journal of Clinical and Translational Hepatology 2022-01-04

Both nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis B infection (CBI) are the most prevalent diseases 25-30% of CBI patients estimated to have co-existing NAFLD, interaction between hepatic steatosis HBV their contribution course is an emerging interest. This study explored association NAFLD effect on response antiviral therapy in pediatric population. All children aged 0-18 years with biopsy-proven or were consecutively collected from January 2010 March 2018 a tertiary...

10.2139/ssrn.3349214 article EN SSRN Electronic Journal 2019-01-01

There is a consensus that indigenous pigs in China are more resistant than modern commercial terms of disease resistance. Generally, the immune response an important part anti-disease capability; however, related mechanism largely puzzling. Here, public transcriptome data peripheral blood mononuclear cells (PBMCs) from Dapulian (Chinese local breed) and Landrace (Commercial after stimulation with polyinosinic-polycytidylic acid (poly I:C, conventional reagent used for simulation viral...

10.3390/ani14233546 article EN cc-by Animals 2024-12-08

Objective: To establish and evaluate diagnostic efficacy applicability of serum Golgi protein (GP) 73 based non-invasive model with other conventional serological indicators for compensated stage hepatitis B cirrhosis. Methods: 666 cases chronic (CHB) who had visited to the Fifth Medical Center People's Liberation Army General Hospital from January 2010 December 2017 were selected as study subjects, classified according cirrhosis into clinical pathological diagnosis group on whether or not...

10.3760/cma.j.issn.1007-3418.2020.01.012 article EN PubMed 2020-01-20

Abstract Single-cell RNA-sequencing (scRNA-seq) is a powerful approach for studying cellular differentiation, but accurately tracking cell-fate transitions can be challenging, especially in disease conditions. Here, we introduce PhyloVelo, computational framework that estimates the velocity of transcriptomic dynamics by using monotonically expressed genes (MEGs), or with expression patterns either increase decrease, don’t cycle, through phylogenetic time. Through integration scRNA-seq data...

10.21203/rs.3.rs-2197712/v1 preprint EN cc-by Research Square (Research Square) 2023-08-01

Oogenesis is a very important process during mammalian development for it the basis of fertilization and zygote development, oogenesis in culture should contribute to various areas, including epigenetics manipulation germ line, advance studies on fertility treatment somatic cell interaction differentiation. Thus, has been studied extensively by means vitro technology over last few years. Mammalian oocytes are derived from founder population primordial cells (PGCs) that determined early...

10.1093/biolreprod/77.s1.221 article EN Biology of Reproduction 2007-07-01
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