A5090539282- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Pressure and Hypertension Studies
- Heart Failure Treatment and Management
- Sepsis Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Sodium Intake and Health
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Medication Adherence and Compliance
- Cardiac Arrhythmias and Treatments
- Cardiac Ischemia and Reperfusion
- Traditional Chinese Medicine Analysis
- Acute Kidney Injury Research
- S100 Proteins and Annexins
- Viral Infections and Immunology Research
- Cardiovascular Effects of Exercise
Tianjin Third Central Hospital
2016-2025
Tianjin Medical University
2016-2025
Tianjin Fire Research Institute
2018-2025
Cell Technology (China)
2025
Tianjin International Joint Academy of Biomedicine
2022-2025
Tianjin Tianhe Hospital
2020-2022
Background Stress hyperglycemia ratio (SHR) was developed to reduce the impact of long-term chronic glycemic factors on stress levels, which have been linked clinical adverse events. However, relationship between SHR and short- prognoses intensive care unit (ICU) patients remains unclear. Methods We retrospectively analyzed 3,887 ICU (cohort 1) whose initial fasting blood glucose hemoglobin A1c data within 24 hours admission were available 3,636 2) who followed-up for 1-year using Medical...
Acute myocardial infarction (AMI) is often present in old populations and rare young people. Its incidence significantly increased recent years. The mechanism disease course of AMI people are probably different from that population. aim this study was to analyze clinical risk factors STEMI patients. Data collected consecutive patients ≤ 44 years age (young; n = 86) 60–74 (old; 65) diagnosed with STEMI, 79 age-matched without coronary artery (CAD), hospitalized between January 2009 June 2013....
ABSTRACT Objective To investigate the correlation between non‐invasive cardiac function monitoring indexes and recent adverse prognosis in patients with STEMI. The hemodynamic high diagnostic value were selected to construct a new risk prediction model combined GRACE scores, efficiency of was evaluated. Methods STEMI who met inclusion exclusion criteria selected. All followed for 6 months major cardiovascular events (MACE). analyzed by univariate multivariate logistic regression. ROC curve...
Objectives To assess the prognostic efficacy of innovative inflammatory indicators, specifically neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR), in conjunction with Global Registry Acute Coronary Events (GRACE) score, for predicting adverse in-hospital outcomes among patients diagnosed ST-segment elevation myocardial infarction (STEMI). Design setting This study is a single-centre retrospective analysis STEMI treated at Cardiology Department Tianjin Third Central...
Abstract Background: The Shexiang Baoxin Pill (MUSKARDIA) has been used for treating coronary artery disease (CAD) and angina more than 30 years in China. Nevertheless, methodologically sound trials on the use of MUSKARDIA CAD patients are scarce. aim study is to determine effects as an add-on optimal medical therapy (OMT) with stable CAD. Methods: A total 2674 participants from 97 hospitals China were randomized 1:1 a or placebo group 24 months. Both groups received OMT according local...
Background: Compared with a classic wrist puncture for radial artery catheterization, distal has the advantage of reducing incidence occlusion in anatomic and physiological procedures. This study aimed to explore difference clinical effects between approaches percutaneous coronary intervention.
The relevant metabolite biomarkers for risk prediction of early onset ventricular fibrillation (VF) after ST-segment elevation myocardial infarction (STEMI) remain unstudied. Here, we aimed to identify these imetabolites and the important metabolic pathways involved, explore whether metabolites could be used as predictors phenotype. Plasma samples were obtained retrospectively from a propensity-score matched cohort including 42 STEMI patients (21 consecutive VF 21 non-VF). Ultra-performance...
This study was to establish a disease differentiation model for ST-segment elevation myocardial infarction (STEMI) youth patients experiencing ischemia and reperfusion via ultra-performance liquid chromatography mass spectrometry (UPLC/MS) platform, which searches closely related characteristic metabolites metabolic pathways evaluate their predictive value in the prognosis after discharge.Forty-seven consecutive STEMI (23 under 45 years of age, referred here as "youth," 24 "elderly"...
Abstract The severity and complexity evaluation of coronary artery disease in patients with heart (CHD) require objective accurate prognosis indexes. We assessed the relationship between lncRNA-Ang362 CHD after percutaneous intervention (PCI). Clinical follow-up data were prospectively collected. LncRNA-Ang362 levels detected by real-time quantitative polymerase chain reaction. Survival rate was calculated Kaplan–Meier method, risk ratios 95% confidence intervals computed using univariate...
The ability of blood transcriptome analysis to identify dysregulated pathways and outcome-related genes following myocardial infarction remains unknown. Two gene expression datasets (GSE60993 GSE61144) were downloaded from Gene Expression Omnibus (GEO) Datasets altered plasma transcriptomes in patients with ST-segment elevated (STEMI) undergoing primary percutaneous coronary intervention. GEO2R, Ontology/Kyoto Encyclopedia Genes Genomes annotations, protein-protein interaction analysis,...
Objective: Hyperglycemia-mediated cardiomyocyte damage is associated with inflammation and AMPK inactivation.Aim: The aim of our study to explore the protective effects exerted by liraglutide on pathway glucagon-like peptide 1 receptor in diabetic cardiomyopathy.Methods: Cardiomyocytes were treated high-glucose stress viability was determined via (3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide assay. Besides, LDH release, immunofluorescence, qPCR used verify influence...
BACKGROUND This study was designed as an external evaluation of potentially relevant models for acute myocardial infarction (AMI) with extracorporeal cardiopulmonary resuscitation (E-CPR). MATERIAL AND METHODS Twenty AMI adults that met criteria were retrospectively analyzed from January 2009 to 2015. Six possible - ENCOURAGE, SAVE, ECPR, GRACE, SHOCK, and a simplified risk chart identified by literature review model scores calculated based on original data. Acute Physiology Chronic Health...
The main objective of this study is to explore the clinical effect and hemorheology changes three drugs combination (misoprostol tablets Chanfukang granules combined with oxytocin) in treatment postpartum hemorrhage puerpera. 80 women admitted from November 2014 January 2022 were divided into control groups given different drug treatments. After taking medication, total efficacy, bleeding scores, height uterine fundus after 3 d involution 10 blood rheology changes, milk secretion volume,...
<title>Abstract</title> <bold>Background: </bold>Hypertension combined with CKD is on the rise in middle-aged and elderly people. However, association of early subclinical decline kidney function long-term mortality these populations remains unclear. In this study, we developed a novel method for evaluating patients hypertension predicting their survival outcomes based thresholds estimated glomerular filtration rate (eGFR). <bold>Methods: </bold>We constructed retrospective cohort study...
Psychological distress, including anxiety and depression, is not only prevalent in patients with coronary heart disease (CHD) but can actually predict adverse clinical events. Therefore, the necessity of addressing psychological problems among CHD to improve their treatment results increasingly acknowledged. This study's objective was examine prognostic impact depression on major cardiovascular events (MACEs) physical function acute syndrome (ACS).
Renal dysfunction is associated with increased mortality and length of hospital stay in critically ill patients. However, it remains unclear whether the early administration an angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) for intensive care unit patients renal reduced in-hospital mortality. We conducted a retrospective analysis who received ACEI/ARB within 72 hours after being hospitalized. Patients were selected from Medical Information Mart Intensive...
Abstract There lacks real‐world study with a large sample size assessing olmesartan medoxomil‐amlodipine besylate (OM‐AML) tablet. Therefore, this aimed to evaluate the efficacy and safety of OM‐AML tablet in patients essential hypertension. Totally, 1341 from 36 medical centers hypertension who took (20/5 mg) were analyzed current prospective, single‐arm, multi‐center, (SVK study). Seated systolic blood pressure (SeSBP) seated diastolic (SeDBP) at baseline, week (W)4 W8 measured. The mean...
Nonischemic cardiomyopathy (NICM) is a group of noncoronary heterogonous myocardial diseases. The nature NICM has impeded its diagnosis. In the present case series, we demonstrate added value using contrast echocardiography in characterization NICM. Two patients advanced age were admitted for possible acute coronary syndrome, which was subsequently excluded by angiography. Conventional and revealed characteristic structural dynamic features left ventricle that compatible with two distinct...