- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Identification and Quantification in Food
- Primate Behavior and Ecology
- Amphibian and Reptile Biology
- Animal Behavior and Reproduction
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Bat Biology and Ecology Studies
- Aquaculture disease management and microbiota
- Immune Response and Inflammation
- Animal Nutrition and Physiology
- Livestock and Poultry Management
- interferon and immune responses
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- HIV Research and Treatment
- Artificial Intelligence in Law
- Wildlife Ecology and Conservation
- Gut microbiota and health
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic and phenotypic traits in livestock
- Antimicrobial Peptides and Activities
- Chemokine receptors and signaling
- Amoebic Infections and Treatments
Sichuan Agricultural University
2015-2024
Sun Yat-sen University
2011
Kunming Institute of Zoology
2004-2005
Chinese Academy of Sciences
2004-2005
Abstract Background: Since the domestication of red jungle fowls (Gallus gallus; dating back to ~10 000 B.P.) in Asia, domestic chickens gallus domesticus) have been subjected combined effects natural selection and human-driven artificial selection; this has resulted marked phenotypic diversity a number traits, including behavior, body composition, egg production, skin color. Population genomic variations through diversifying not fully investigated. Findings: The whole genomes 78 were...
There are hundreds of phenotypically distinguishable domestic chicken breeds or lines with highly specialized traits worldwide, which provide a unique opportunity to illustrate how selection shapes patterns genetic variation. many local in China.Here, we population genome landscape variations 86 chickens representing 10 diverse breeds. Genome-wide analysis indicated that sex chromosomes have less diversity and under stronger than autosomes during domestication adaptation. We found an...
The red panda is the only living species of genus Ailurus. Like giant pandas, pandas are also highly specialized to feed mainly on fibrous bamboo. Although several studies have focused gut microbiota in panda, little known about panda. In this study, we characterized fecal from both wild (n = 16) and captive 6) using a pyrosequecing based approach targeting V1-V3 hypervariable regions 16S rRNA gene. Distinct bacterial communities were observed between two groups membership structure. Wild...
Macaques are the most widely distributed nonhuman primates and used as animal models in biomedical research. The availability of full-genome sequences from them would be essential to both primate evolutionary studies. Previous studies have reported whole-genome rhesus macaque (Macaca mulatta) cynomolgus (M. fascicularis, CE), which belong fascicularis group. Here, we present a 37-fold coverage genome sequence Tibetan thibetana; TM). TM is an endemic species China belonging sinica On basis...
Abstract Background The rhesus macaque (RM, Macaca mulatta) is the most important nonhuman primate model in biomedical research. We present first genomic survey of wild RMs, sequencing 81 geo-referenced individuals five subspecies from 17 locations China, a large fraction species' natural distribution. Results Populations were structured into genetic lineages on mainland and Hainan Island, recapitulating current designations. These are estimated to have diverged 125.8 51.3 thousand years...
Island vertebrates have evolved a number of morphological, physiological, and life history characteristics that set them apart from their mainland relatives. However, to date, the evolution metabolism its impact on vulnerability extinction insular remains poorly understood. This study used metabolic data 2813 species tetrapod vertebrates, including 695 ectothermic 2118 endothermic species, reveal island mammals birds convergent strategies toward slow pace life. Insularity was associated with...
Abstract There have been many reports on the genetic mechanism in rhesus macaques (RMs) for environmental adaptation to high altitudes, but synergistic involvement of gut microbiota this remains unclear. Here we performed fecal metagenomic and metabolomic studies samples from high- low-altitude populations assess role RMs high-altitude environments. Microbiota taxonomic annotation yielded 7471 species. were 37 bacterial species whose abundance was significantly enriched populations, 16 which...
Platysternon megacephalum is the only living representative species of Platysternidae and three subspecies remain: P. m. megalorcephalum, shiui, peguense. However, previous reports implied that peguense has distinct morphological molecular features. The characterization mitogenome been accepted as an efficient means phylogenetic evolutionary analysis. Hence, this study first determined complete with aim to identify structure variability through comparative Furthermore, relationship was...
Rhesus macaques living in western Sichuan, China, have been separated into several isolated populations due to habitat fragmentation. Previous studies based on the neutral or nearly markers (mitochondrial DNA microsatellites) showed high levels of genetic diversity and moderate differentiation Sichuan rhesus macaques. Variation at major histocompatibility complex (MHC) loci is widely accepted as being maintained by balancing selection, even with a low level variability some species. However,...
Garrulax sannio (Passeriformes, Timaliidae) was the medium-sized bird, whose plumage color similar for both sexes. The complete sequence of mitochondrial DNA genome from G. used polymerase chain reaction method. (17 840 bp in length) contained 13 protein-coding genes, 2 rRNA (12S and 16S) 22 tRNA genes control regions (D-loop). base composition mitogenome A + T percentage 52.22%. It is slightly higher than G C 47.78% which with other vertebrates. Through constructed phylogenetic tree, we...
Tibetan macaque (Macaca thibetana) is a threatened primate species endemic to China. Population genetic and phylogenetic analyses were conducted in 66 individuals from Sichuan (SC), Huangshan (HS), Fujian (FJ) based on 477-bp fragment of mitochondrial DNA control region. Four new haplotypes defined, relatively high level diversity was first observed FJ populations (Hd = 0.7661). Notably, continuous approximately 10 bp-fragment deletion near the 5′ end mtDNA region both HS when compared with...
摘要: 猕猴(Macaca mulatta)是最理想的医学实验灵长类动物, 且为国家二级保护动物。 为了解中国猕猴主要组 织相容复合体(Major histocompatibility complex, MHC)基因的遗传多态性背景, 为它们在生物医学研究中的应 用及其遗传资源的保护提供一定的科学依据, 文章采用变性梯度凝胶电泳(Denaturing gradient gel electrophoresis, DGGE)和克隆测序技术分析了 106 个四川野生猕猴 MHC
We describe the complete mitochondrial genome of Endangered fish Anabarilius liui yalongensis. It is a circular molecule 16,608 bp in size, and all genes show typical gene arrangement conforming to vertebrate consensus. The cytochrome c oxidase subunit I (COI) sequence A. yalongensis other 21 species from 14 genera were used for phylogenetic analysis by Bayesian inference maximum likelihood methods. topology demonstrated that clustered with grahami are closely Hemiculter branch within...
Garrulax elliotii belonged to Passeriformes, one of the members Timaliidae family. It was a kind unique and resident species habitat in evergreen broadleaf forest alpine shrub belt. The complete mitochondrial genome G. constituted by 13 protein-coding genes (PCGs), 22 transfer ribonucleic acid (tRNA) genes, two Ribosomal RNA (12SrRNA 16SrRNA) control regions (D-loop) genes. ND6 eight tRNA (tRNAGln, tRNAAla, tRNAAsn, tRNACys, tRNATyr, tRNASer(UCN), tRNAPro, tRNAGlu) encoded on light strand,...
Amphioxus is a crucial organism for the study of vertebrate evolution. Although genomic BAC library Branchiostoma floridae has been constructed, we report here another construction its distant relative species belcheri. The amphioxus established in present consists 45,312 clones arrayed one hundred and eighteen 384-well plates. average insert fragment size was 120 kb estimated by Pulsed Field Gel Electrophoresis (PFGE) analysis 318 randomly selected clones. representation about 12 equivalent...