A5012304305- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer, Lipids, and Metabolism
- Glycosylation and Glycoproteins Research
- Pancreatic and Hepatic Oncology Research
- Renal cell carcinoma treatment
- Cancer, Hypoxia, and Metabolism
- Metastasis and carcinoma case studies
- Heat shock proteins research
- Pelvic and Acetabular Injuries
- Polyamine Metabolism and Applications
- Cancer Mechanisms and Therapy
- Wnt/β-catenin signaling in development and cancer
- Medical Research and Treatments
- MRI in cancer diagnosis
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Biomedical Research and Pathophysiology
- Peroxisome Proliferator-Activated Receptors
- Chronic Kidney Disease and Diabetes
- Extracellular vesicles in disease
- Cytokine Signaling Pathways and Interactions
- Genetic factors in colorectal cancer
Nanjing Medical University
2008-2021
Wuxi No.2 People's Hospital
2012-2021
Xian Yang Central Hospital
2021
Second Hospital of Shanxi Medical University
2018
Shanxi Medical University
2018
Wuxi People's Hospital
2016-2017
The present research aimed to evaluate the prognostic value of a novel risk classification microvascular invasion (MVI) in hepatocellular carcinoma (HCC) after resection.A total 295 consecutive HCC patients underwent hepatectomy were included our study. We evaluated degree MVI according following three features: number invaded microvessels (≤5 vs >5), invading cells (≤ 50 >50), distance from tumor edge (≤1 cm >1 cm).All divided into groups factors MVI: non-MVI group (n=180), low-MVI (n=60)...
The aim of this study was to investigate the prognostic value and preoperative predictors microvascular invasion (MVI) in solitary hepatocellular carcinoma (HCC) ≤ 5 cm without macrovascular invasion.A total 233 consecutive HCC patients underwent curative hepatectomy were included our study. Independent risk factors influencing prognosis identified, for MVI determined.Multivariate regression analysis identified ICG-R15, BCLC staging as independent overall survival rate. Type resection...
Estrogen-related receptor-α (ERRα) is a nuclear receptor of transcription factor that binds to estrogen responsive elements and estrogen-related elements. involved in metabolic processes implicated the progression growth several human malignancies. However, biologic role clinical significance ERRα gallbladder cancer (GBC) remains be clarified. Here, we reported protein expression was notably higher GBC tissues than cholecystitis tissues, aberrantly positively correlated with advanced TNM...
Gallbladder cancer (GBC), the sixth most common gastrointestinal tract cancer, poses a significant disease burden in China. However, no national representative data are available on clinical characteristics, treatment and prognosis of GBC Chinese population.The Research Group Cancer (CRGGC) study is multicentre retrospective registry cohort study. Clinically diagnosed patient with will be identified from 1 January 2008 to December, 2019, by reviewing electronic medical records 76 tertiary...
The purpose of this study was to compare negative-contrast CT cholangiopancreatography (CTCP) and angiography (CTA) with MRCP MR (MRA) for the preoperative evaluation malignant perihilar biliary obstruction.Twenty-one patients pathologically proven obstructions who had undergone both MRI examinations were reviewed retrospectively. Two reviewers independently analyzed two image sets-the CTCP CTA images (i.e., set) MRA set)-in preoperatively evaluating classification obstruction, hepatic...
Prognostic significance of regional lymphadenectomy in T1b gallbladder cancer: Results from 24 hospitals China
Interleukin (IL)‑20 is a member of the IL‑10 family cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, potential role IL‑20 hepatocellular carcinoma (HCC) progression not yet investigated. In present study, it was observed that mRNA and protein levels were markedly increased HCC tissues examined via reverse transcription‑quantitative polymerase chain reaction immunohistochemical staining. addition, expression significantly associated with tumor...
The present study aimed to investigate the long-term and perioperative outcomes of precise hepatic pedicle dissection in anatomical resection (precise AR) vs non-anatomical (NAR) for hepatocellular carcinoma (HCC) patients.Data from a total 270 consecutive HCC patients who underwent curative hepatectomy were retrospectively collected. Propensity score matching (PSM) analysis was performed. AR NAR analyzed using Kaplan-Meier method Cox proportional hazards model.The 1-, 3-, 5-year overall...
The nuclear estrogen‑related receptor‑α (ERRα) is an orphan receptor that has been identified as a transcriptional factor. Peroxisome proliferator‑activated receptor‑γ (PPARγ) coactivator‑1‑α (PGC‑1α) and PPARγ coactivator‑1‑β (PGC‑1β) act the co‑activators of ERRα. Our previous study reported activated ERRα promoted invasion proliferation gallbladder cancer cells by promoting PI3K/AKT phosphorylation. Therefore, aim current was to investigate whether phosphorylation could enhance activity...
Objective To summarize the imaging features of computed tomography (CT )and magnetic resonance (MRI) combined with multi-technology and compare its effects in preoperative evaluation malignant perihilar biliary obstruction. Methods The clinical data 20 patients receiving CT MRI who were diagnosed obstruction by pathological examination at Wuxi Second People's Hospital between January 2008 April 2014 retrospectively analyzed. Patients negative-contrast cholangiopancreatography (nCTCP)...
Objective To investigate the value of diffusion weighted magnetie resonance imaging and apparent coefficient (ADC) in diagnosis pancreatic cancer.Methods The clinical data 36 patients with pancreatie cancer who were admitted to Wuxi No.2 People's Hospital from March 2009 June 2011 retrospectively analyzed,and 30 healthy volunteers collected.All candidates received examination.The signal intensity ratios ( SIRs ) pericancerous tissues T1 weighted-images (T1WI),T2 (T2WI) (DWI) compared by...
Abstract Background: Gallbladder cancer (GBC) is the most common malignant tumour of bile duct with a poor prognosis. The estrogen-related receptor alpha (ERRα) nuclear that has been associated metabolic processes and progression. Increased ERRα shown in endocrine-related non-endocrine-related cancer. Nevertheless, its role GBC remains unknown. Methods: expression was analyzed by immunohistochemistry 59 samples. Its association clinicopathologic characteristics evaluated. effect on cell...