A5102017301- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Cancer, Hypoxia, and Metabolism
- Sepsis Diagnosis and Treatment
- Biosensors and Analytical Detection
- Machine Learning in Healthcare
- Advanced Technologies in Various Fields
- Renal Diseases and Glomerulopathies
- COVID-19 and healthcare impacts
- Microbial Community Ecology and Physiology
- Software Engineering Research
- Digitalization and Economic Development in Agriculture
- Education and Professional Development
- Digital Marketing and Social Media
- E-commerce and Technology Innovations
- Tissue Engineering and Regenerative Medicine
- Dispute Resolution and Class Actions
- Dermatological and COVID-19 studies
- Adrenal and Paraganglionic Tumors
- Crime Patterns and Interventions
- World Trade Organization Law
- Educational Methods and Teacher Development
Army Medical University
2025
Southwest Hospital
2025
Shanghai Sunshine Rehabilitation Center
2024
Georgia Institute of Technology
2024
Shandong Normal University
2024
Tangshan People's Hospital
2023
Defence Electronics Research Laboratory
2023
Wenzhou Medical University
2009-2022
Second Affiliated Hospital of Harbin Medical University
2022
Xinqiao Hospital
2022
Severity prediction of COVID-19 remains one the major clinical challenges for ongoing pandemic. Here, we have recruited a 144 patient cohort, resulting in data matrix containing 3,065 readings 124 types measurements over 52 days. A machine learning model was established to predict disease progression based on cohort consisting training, validation, and internal test sets. panel eleven routine factors constructed classifier severity prediction, achieving accuracy 98% discovery set. Validation...
Abstract Metabolic reprogramming of tumor cells dynamically reshapes the distribution nutrients and signals in microenvironment (TME), affecting intercellular interactions resulting metabolic immune suppression. Increased glucose uptake metabolism are characteristic many tumors. Meanwhile, progression colorectal carcinoma (CRC) relies on lipid metabolism. Therefore, investigating role glucolipid immunity contributes to identifying new targets for suppression intervention CRC. Our previous...
Currently, with the joint efforts of educators and strong support from whole society, China's basic education has achieved great success in curriculum reform. The is also constantly being reformed, among which physics after reform undergone significant reforms teaching methods, tools, thinking, puts forward new requirements for development teachers' own abilities. This article based on my practice, through visits investigations, as well analysis changes under concept. It attempts to redefine...
In teaching poses significant challenges for clinical doctors and medical students. Students frequently struggle to apply theoretical knowledge in real contexts. We explore the joint discussion of flipped classroom urological surgery theory case-based learning (CBL) applies effects. This study aims assess effectiveness integrating Case-Based Learning with a Flipped Classroom (FC) approach context nephrology bedside teaching. Methods: Select students from International Education College Hebei...
Background: On December 8, 2019, the first new coronavirus case was discovered in Wuhan, China, and an intensive outbreak incepted next month (about January 20). Virologicalists epidemiologists predict that it will reach a peak about 90 days fade away till end 4 months (Early April), entire epidemic terminate early May. The daily rise confirmed cases increase number of communities on map always hit nerves panic. 31, 2020, World Health Organization (WHO) declared China 's "public health...
Abstract Serum lactate dehydrogenase (LDH) has been established as a prognostic indicator given its differential expression in COVID‐19 patients. However, the molecular mechanisms underneath remain poorly understood. In this study, 144 patients were enrolled to monitor clinical and laboratory parameters over 3 weeks. LDH was shown elevated on admission declined throughout disease course, ability classify patient severity outperformed other biochemical indicators. A threshold of 247 U/L serum...
We systematically evaluated the photobiological safety of mainstream ST-PV devices and fabricated a series high-performance human-friendly with LUE values exceeding 5.0% low skin/eye damage levels for human beings.
RT-PCR is the primary method to diagnose COVID-19 and also used monitor disease course. This approach, however, suffers from false negatives due RNA instability poses a high risk medical practitioners. Here, we investigated potential of using serum proteomics predict viral nucleic acid positivity during COVID-19. We analyzed proteome 275 inactivated samples 54 out 144 patients shortlisted 42 regulated proteins in severe group 12 non-severe group. Using these several key clinical indexes,...
ABSTRACT Severity prediction of COVID-19 remains one the major clinical challenges for ongoing pandemic. Here, we have recruited a 144 patient cohort consisting training, validation, and internal test sets, longitudinally recorded 124 routine laboratory parameters, built machine learning model to predict disease progression based on measurements from first 12 days since onset when no became severe. A panel 11 factors, including oxygenation index, basophil counts, aspartate aminotransferase,...
Large Language Models (LLMs) have recently showcased remarkable reasoning abilities. However, larger models often surpass their smaller counterparts in tasks, posing the challenge of effectively transferring these capabilities from models. Existing approaches heavily rely on extensive fine-tuning data or continuous interactions with a superior teacher LLM during inference. We introduce principle-based teacher-student framework called ``Teaching via Principle Discovery'' (TPD) to address...
Severe COVID-19 patients account for most of the mortality this disease. Early detection and effective treatment severe remain major challenges. Here, we performed proteomic metabolomic profiling sera from 46 53 control individuals. We then trained a machine learning model using measurements training cohort 18 non-severe 13 patients. The correctly classified with an accuracy 93.5%, was further validated ten independent patients, seven which were classified. identified molecular changes in...
Background: New coronavirus pneumonia (COVID-19) outbreak and caused global human respiratory tract infections since 2019, however, the pattern of SARS-CoV-2 intestinal is not well understood. Methods: The virological epidemiological researches prompted us to speculate that may serve as a supplementary route acquire infection. By identifying evidence virus infection in 343 stool specimen 575 throat swabs samples 137 clinical patient who were confirmed diagnosis with COVID-19 subsequently....
While online advertising is one of the major sources income for search engines, pumping up incomes from business advertisements while ensuring user experience becomes a challenging but emerging area. Designing high-quality with persuasive content has been proved as way to increase revenues through improving Click-Through Rate (CTR). However, it difficult scale design ads, due lack automation in creativity. In this paper, we present Commonsense-Enriched Advertisement on Search Engine (CHASE)...
Background The long-term consequences of human umbilical cord-derived mesenchymal stem cell (UC-MSC) treatment for COVID-19 patients are yet to be reported. This study assessed the 1-year outcomes in with severe COVID-19, who were recruited our previous UC-MSC clinical trial.Methods: In this prospective, longitudinal, cohort study, 100 enrolled phase 2 trial prospectively followed up at 3-month intervals 1 year evaluate safety and effectiveness treatment. primary endpoint was an altered...
Background The impact of anticancer therapy and related clinical factors on the severity COVID-19 in cancer patients during Omicron pandemic has not been established. recent outbreak China caused predominantly by BA.5.2 BF.7 strains provided us with opportunity to observe objectively this strain oncology patients. We initiated two–center retrospective study determine anti-cancer treatment, other factors, characteristics infected coronavirus SARS-CoV-2 variant China. Methods retrospectively...
Complex and quick change of the social environment so that today's enterprises are faced with unprecedented survival development pressures, continuous innovation is only way to win enterprise.In order accelerate innovation, ease pressure survival, many companies began focus on employee innovation.After entering 21st century, economy becoming more globalized, political trend diversified business complicated.The employees new economic era such as generation staff knowledge workers required...
The novel coronavirus pneumonia COVID-19 is caused by the SARS-CoV-2, which highly contagious, has a long incubation period, and can be detected in patients’ tears conjunctival secretions. In this study, we describe our experience regarding necessary protective measures that need to taken during ophthalmic examination treatment. authors reviewed clinical work arrangements epidemic situation at Eye Hospital of Wenzhou Medical University China analyzed prevention control were applied laser...
In urban transportation networks, crime diffuses as criminals travel through the networks and look for illicit opportunities. It is important to first model this diffusion in order recommend actions or patrol policies control of such crime. Previously, game theory has been used policy recommendations, but these applications security have not modeled that comes about due seeking opportunities; instead focus on highly strategic adversaries plan attacks advance. To overcome limitation previous...
Abstract Serum lactate dehydrogenase (LDH) has been established as a prognostic indicator given its differential expression in COVID-19 patients. However, the molecular mechanisms underneath remain poorly understood. In this study, 144 patients were enrolled to monitor clinical and laboratory parameters over three weeks. was shown elevated on admission declined throughout disease course, ability classify patient severity outperformed other biochemical indicators. A threshold of 247 U/L serum...