Chrysovalantou Nikolaidou

ORCID: 0000-0003-4217-9400
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Advanced MRI Techniques and Applications
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Cardiac tumors and thrombi
  • Coronary Interventions and Diagnostics
  • Kawasaki Disease and Coronary Complications
  • Pericarditis and Cardiac Tamponade
  • Long-Term Effects of COVID-19
  • Cardiac Arrhythmias and Treatments
  • Coronary Artery Anomalies
  • Cardiovascular Disease and Adiposity
  • Advanced X-ray and CT Imaging
  • Cardiovascular Effects of Exercise
  • Pulmonary Hypertension Research and Treatments
  • Acute Myocardial Infarction Research
  • Infective Endocarditis Diagnosis and Management
  • Integrated Circuits and Semiconductor Failure Analysis
  • Vascular anomalies and interventions
  • Genetic Neurodegenerative Diseases
  • Birth, Development, and Health
  • Vascular Anomalies and Treatments

University of Oxford
2019-2024

John Radcliffe Hospital
2019-2024

Oxford University Hospitals NHS Trust
2024

Oxford BioMedica (United Kingdom)
2021-2024

Gloucestershire Health and Care NHS Foundation Trust
2024

National Institute for Health Research
2021-2023

Oxford Health NHS Foundation Trust
2023

Collaborative Group (United States)
2023

Restore America's Estuaries
2023

NIHR Leicester Biomedical Research Centre
2023

Background: Myocardial scars are assessed noninvasively using cardiovascular magnetic resonance late gadolinium enhancement (LGE) as an imaging gold standard. A contrast-free approach would provide many advantages, including a faster and cheaper scan without contrast-associated problems. Methods: Virtual native (VNE) is novel technology that can produce virtual LGE-like images the need for contrast. VNE combines cine T1 maps to artificial intelligence. was developed patients with previous...

10.1161/circulationaha.122.060137 article EN cc-by Circulation 2022-09-20
Betty Raman Celeste McCracken Mark Philip Cassar Alastair J. Moss Lucy Finnigan and 95 more Azlan Helmy Abd Samat Godwin Ogbole Elizabeth M. Tunnicliffe Fidel Alfaro‐Almagro Ricarda Menke Cheng Xie Fergus Gleeson Elena Lukaschuk Hanan Lamlum Kevin McGlynn Iulia A. Popescu Zeena‐Britt Sanders Laura Saunders Stefan K. Piechnik Vanessa M. Ferreira Chrysovalantou Nikolaidou Najib M. Rahman Ling‐Pei Ho Victoria Harris Aarti Shikotra Amisha Singapuri Paul Pfeffer Charlotte Manisty Onn Min Kon Mark Beggs Declan P. O’Regan Jonathan Fuld Jonathan Weir‐McCall Dhruv Parekh Richard P. Steeds Krisnah Poinasamy Dan J Cuthbertson Graham J. Kemp Malcolm G. Semple Alex Horsley Chris Miller Caitlin E. O’Brien Ajay M. Shah Amedeo Chiribiri Olivia C. Leavy Matthew Richardson Omer Elneima Hamish McAuley Marco Sereno Ruth Saunders Linzy Houchen‐Wolloff Neil Greening Charlotte E. Bolton Jeremy Brown Gourab Choudhury Nawar Diar Bakerly Nicholas Easom Carlos Echevarria Michael Marks John R. Hurst Mark G. Jones Dan Wootton Trudie Chalder Melanie J. Davies Anthony De Soyza John Geddes William Greenhalf Luke Howard Joseph Jacob William D‐C Man Peter Openshaw Joanna C. Porter Matthew Rowland J. T. Scott Sally Singh David Thomas Mark Toshner Keir Lewis Liam G. Heaney Ewen M. Harrison Steven Kerr Annemarie B Docherty Nazir Lone Jennifer K Quint Aziz Sheikh Bang Zheng Gisli Jenkins Eleanor Cox Susan Francis Mark Halling‐Brown James D. Chalmers John P. Greenwood Sven Plein Paul Hughes A. A. Roger Thompson Sarah Rowland–Jones Jim M. Wild Matt Kelly Thomas A. Treibel Steven Bandula

<h2>Summary</h2><h3>Introduction</h3> The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed evaluate excess burden abnormalities after hospitalisation with COVID-19, their determinants, and explore associations patient-related outcome measures. <h3>Methods</h3> In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included Tier...

10.1016/s2213-2600(23)00262-x article EN cc-by The Lancet Respiratory Medicine 2023-09-22

Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is the gold standard for noninvasive myocardial tissue characterization but requires intravenous contrast agent administration. It highly desired to develop a agent-free technology replace LGE faster and cheaper CMR scans.

10.1161/circulationaha.121.054432 article EN cc-by Circulation 2021-07-07

In suspected non-ST-segment-elevation myocardial infarction (NSTEMI), this presumed diagnosis may not hold true in all cases, particularly patients with non-obstructive coronary arteries (NOCA). Additionally, multi-vessel artery disease (MVD), the infarct-related (IRA) be incorrect. To assess diagnostic utility of cardiovascular magnetic resonance (CMR) before invasive angiogram (ICA) NSTEMI. 100 consecutive stable acute NSTEMI (70% male, age 62±11 years) prospectively underwent CMR pre-ICA...

10.1016/j.jcmg.2024.05.007 article EN cc-by JACC. Cardiovascular imaging 2024-06-05

Left atrial (LA) size and function are known predictors of new onset fibrillation (AF) in hypertrophic cardiomyopathy (HCM) patients. Components LA deformation including reservoir, conduit, booster provide additional information on mechanics. Whether or not can augment our ability to predict the risk AF HCM patients beyond standard measurements is unknown. We assessed size, function, cardiovascular magnetic resonance (CMR) 238 genotyped compared this with twenty age, sex, blood pressure body...

10.1186/s12968-021-00793-6 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2021-03-01

Background: A routine diagnostic work-up does not identify structural abnormalities in a substantial proportion of patients with idiopathic ventricular arrhythmias (VAs). We investigated the added value cardiac magnetic resonance (CMR) imaging this group patients. Methods: single-centre prospective study was undertaken 72 (mean age 46 ± 16 years; 53% females) frequent premature contractions (PVCs ≥ 500/24 h) and/or non-sustained tachycardia (NSVT), an otherwise normal electrocardiogram,...

10.3390/diagnostics11061109 article EN cc-by Diagnostics 2021-06-18

Acquiring high-quality cardiac magnetic resonance (CMR) images in patients with frequent ventricular arrhythmias remains a challenge. We examined the safety and efficacy of procainamide when administered on scanner table prior to CMR scanning suppress ectopy acquire images. Fifty consecutive (age 53.0 [42.0–58.0]; 52% female, left ejection fraction 55 ± 9%) were scanned 1.5 T using standard protocol. Procainamide was at intermittent intravenous bolus doses 50 mg every minute until...

10.3390/diagnostics11020178 article EN cc-by Diagnostics 2021-01-27

<h3>Introduction</h3> Non-ST-segment elevation myocardial infarction (NSTEMI) results in approximately 50,000 hospital admissions the UK every year with up to 90% undergoing invasive coronary angiograms (ICA). A non-invasive strategy using cardiovascular magnetic resonance (CMR) before ICA suspected NSTEMI has potential diagnose non-ischaemic pathologies and obviate need for ICA. Furthermore, cases of acute (MI) multi-vessel artery disease (CAD), it can identify infarct related (IRA), which...

10.1136/heartjnl-2024-bcs.177 article EN cc-by-nc Imaging 2024-05-27

Electrical storm (ES) is not uncommon among patients with an implantable cardioverter defibrillator (ICD) in situ. Catheter ablation (CA) may suppress the arrhythmia acute setting and prevent ES recurrence. Nineteen consecutive ICD situ presenting underwent electrophysiologic studies followed by CA. CA outcome was classified as a complete success if both clinical non-clinical tachycardia were successfully ablated, partial ≥1 episodes still inducible post–CA, failure could be abolished....

10.1016/j.hjc.2017.01.019 article EN cc-by-nc-nd Hellenic Journal of Cardiology 2017-01-01

Uncovering the skeleton in heart: an unusual case of mitral annular calcification extending to left ventricular myocardium Chrysovalantou Nikolaidou, Nikolaidou Division Cardiovascular Medicine, Radcliffe Department University Oxford, John Hospital, Headley Way, Headington, OX3 9DU, UK Corresponding author. Tel: +44 7821643930. E-mail: chrysovalantou.nikolaidou@cardiov.ox.ac.uk https://orcid.org/0000-0003-4217-9400 Search for other works by this author on: Oxford Academic PubMed Google...

10.1093/ehjci/jeaa121 article EN European Heart Journal - Cardiovascular Imaging 2020-04-21

Background: Angina pectoris, the main manifestation of coronary artery disease has an unfavorable impact on quality life. The aim this study was to assess Health-Related Quality Of Life (HRQoL) in patients with Stable Coronary Artery Disease (SCAD) and explore possible relationships between HRQoL risk factors for ischaemic heart disease, Canadian Cardiovascular Society (CCS) angina severity class, extent myocardial ischaemia Single Photon Emission Computed Tomography Myocardial Perfusion...

10.52768/2766-7820/1585 article EN Journal of Clinical Images and Medical Case Reports 2022-01-19
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