- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac tumors and thrombi
- Coronary Interventions and Diagnostics
- Kawasaki Disease and Coronary Complications
- Pericarditis and Cardiac Tamponade
- Long-Term Effects of COVID-19
- Cardiac Arrhythmias and Treatments
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Advanced X-ray and CT Imaging
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Integrated Circuits and Semiconductor Failure Analysis
- Vascular anomalies and interventions
- Genetic Neurodegenerative Diseases
- Birth, Development, and Health
- Vascular Anomalies and Treatments
University of Oxford
2019-2024
John Radcliffe Hospital
2019-2024
Oxford University Hospitals NHS Trust
2024
Oxford BioMedica (United Kingdom)
2021-2024
Gloucestershire Health and Care NHS Foundation Trust
2024
National Institute for Health Research
2021-2023
Oxford Health NHS Foundation Trust
2023
Collaborative Group (United States)
2023
Restore America's Estuaries
2023
NIHR Leicester Biomedical Research Centre
2023
Background: Myocardial scars are assessed noninvasively using cardiovascular magnetic resonance late gadolinium enhancement (LGE) as an imaging gold standard. A contrast-free approach would provide many advantages, including a faster and cheaper scan without contrast-associated problems. Methods: Virtual native (VNE) is novel technology that can produce virtual LGE-like images the need for contrast. VNE combines cine T1 maps to artificial intelligence. was developed patients with previous...
<h2>Summary</h2><h3>Introduction</h3> The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed evaluate excess burden abnormalities after hospitalisation with COVID-19, their determinants, and explore associations patient-related outcome measures. <h3>Methods</h3> In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included Tier...
Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is the gold standard for noninvasive myocardial tissue characterization but requires intravenous contrast agent administration. It highly desired to develop a agent-free technology replace LGE faster and cheaper CMR scans.
In suspected non-ST-segment-elevation myocardial infarction (NSTEMI), this presumed diagnosis may not hold true in all cases, particularly patients with non-obstructive coronary arteries (NOCA). Additionally, multi-vessel artery disease (MVD), the infarct-related (IRA) be incorrect. To assess diagnostic utility of cardiovascular magnetic resonance (CMR) before invasive angiogram (ICA) NSTEMI. 100 consecutive stable acute NSTEMI (70% male, age 62±11 years) prospectively underwent CMR pre-ICA...
Left atrial (LA) size and function are known predictors of new onset fibrillation (AF) in hypertrophic cardiomyopathy (HCM) patients. Components LA deformation including reservoir, conduit, booster provide additional information on mechanics. Whether or not can augment our ability to predict the risk AF HCM patients beyond standard measurements is unknown. We assessed size, function, cardiovascular magnetic resonance (CMR) 238 genotyped compared this with twenty age, sex, blood pressure body...
Background: A routine diagnostic work-up does not identify structural abnormalities in a substantial proportion of patients with idiopathic ventricular arrhythmias (VAs). We investigated the added value cardiac magnetic resonance (CMR) imaging this group patients. Methods: single-centre prospective study was undertaken 72 (mean age 46 ± 16 years; 53% females) frequent premature contractions (PVCs ≥ 500/24 h) and/or non-sustained tachycardia (NSVT), an otherwise normal electrocardiogram,...
Acquiring high-quality cardiac magnetic resonance (CMR) images in patients with frequent ventricular arrhythmias remains a challenge. We examined the safety and efficacy of procainamide when administered on scanner table prior to CMR scanning suppress ectopy acquire images. Fifty consecutive (age 53.0 [42.0–58.0]; 52% female, left ejection fraction 55 ± 9%) were scanned 1.5 T using standard protocol. Procainamide was at intermittent intravenous bolus doses 50 mg every minute until...
<h3>Introduction</h3> Non-ST-segment elevation myocardial infarction (NSTEMI) results in approximately 50,000 hospital admissions the UK every year with up to 90% undergoing invasive coronary angiograms (ICA). A non-invasive strategy using cardiovascular magnetic resonance (CMR) before ICA suspected NSTEMI has potential diagnose non-ischaemic pathologies and obviate need for ICA. Furthermore, cases of acute (MI) multi-vessel artery disease (CAD), it can identify infarct related (IRA), which...
Electrical storm (ES) is not uncommon among patients with an implantable cardioverter defibrillator (ICD) in situ. Catheter ablation (CA) may suppress the arrhythmia acute setting and prevent ES recurrence. Nineteen consecutive ICD situ presenting underwent electrophysiologic studies followed by CA. CA outcome was classified as a complete success if both clinical non-clinical tachycardia were successfully ablated, partial ≥1 episodes still inducible post–CA, failure could be abolished....
Uncovering the skeleton in heart: an unusual case of mitral annular calcification extending to left ventricular myocardium Chrysovalantou Nikolaidou, Nikolaidou Division Cardiovascular Medicine, Radcliffe Department University Oxford, John Hospital, Headley Way, Headington, OX3 9DU, UK Corresponding author. Tel: +44 7821643930. E-mail: chrysovalantou.nikolaidou@cardiov.ox.ac.uk https://orcid.org/0000-0003-4217-9400 Search for other works by this author on: Oxford Academic PubMed Google...
Background: Angina pectoris, the main manifestation of coronary artery disease has an unfavorable impact on quality life. The aim this study was to assess Health-Related Quality Of Life (HRQoL) in patients with Stable Coronary Artery Disease (SCAD) and explore possible relationships between HRQoL risk factors for ischaemic heart disease, Canadian Cardiovascular Society (CCS) angina severity class, extent myocardial ischaemia Single Photon Emission Computed Tomography Myocardial Perfusion...