- Pregnancy and preeclampsia studies
- Cardiovascular Issues in Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and fetal healthcare
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Maternal and Perinatal Health Interventions
- Neonatal Respiratory Health Research
- Congenital Heart Disease Studies
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Cardiovascular Health and Disease Prevention
- Medical and Health Sciences Research
- Preterm Birth and Chorioamnionitis
- Blood groups and transfusion
- Parvovirus B19 Infection Studies
- Pregnancy-related medical research
- Ectopic Pregnancy Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Pelvic floor disorders treatments
- Congenital Diaphragmatic Hernia Studies
- Pediatric Urology and Nephrology Studies
- Health and Medical Studies
- Pregnancy and Medication Impact
- Child and Adolescent Health
University Hospital of Zurich
2024
Helios Kliniken
2015-2021
Helios Dr. Horst Schmidt Kliniken Wiesbaden
2009-2020
Charité - Universitätsmedizin Berlin
2012
Walter de Gruyter (Germany)
2012
Universitäts Frauenklinik
1987-2008
Evangelisches Krankenhaus Bielefeld
2007
University of Tübingen
1989-1998
University Children's Hospital Tübingen
1989-1995
Olgahospital
1993
Abnormally invasive placenta (AIP) poses diagnostic and therapeutic challenges. We analyzed clinical cases with confirmed increta or percreta.Retrospective case series.Multicenter study.Pregnant women AIP.Chart review.Prenatal detection rates, treatment choices, morbidity, mortality short-term outcome.Sixty-six were analyzed. All all but three fetuses survived; 57/64 (89%) had previous uterine surgery. In 26 (39%) the diagnosis was not known before delivery (Group 1), in remaining 40 (61%)...
Abstract Aims: The aim of this study was to investigate the current prenatal “off-label use” cytomegalovirus hyperimmunoglobulin (CMV-HIG) in prevention and treatment congenital CMV (cCMV) infection, including long-term outcome children. Methods: This retrospective observational comprised mothers their children, born between January 1, 2006, October 30, 2010. Prenatal CMV-HIG administered after diagnosis primary infection mother. Clinical virological data were collected from maternal...
First-trimester screening between 11 + 0 and 13 6 weeks with qualified prenatal counseling, detailed ultrasound, biochemical markers maternal factors has become the basis for decisions about further examinations. It detects numerous structural genetic anomalies. The inclusion of uterine artery Doppler PlGF screens preeclampsia fetal growth restriction. Low-dose aspirin significantly reduces prevalence severe preterm eclampsia. Cut-off values define groups high, intermediate low probability....
Die vorliegenden Empfehlungen haben zum Ziel, die perinatologische Versorgung von Schwangeren, Müttern, Neu- und Frühgeborenen risiko-adjustiert interdisziplinär zu organisieren. Dazu ist es erforderlich, genaue Voraussetzungen definieren, für mit unterschiedlichen Risiken den Kliniken vorgehalten werden müssen. vorgeschlagenen Strukturen sind eine wissenschaftlich begründete, bedarfsgerechte hochwertige Perinatalmedizin.
Schlulßfolgerung: Es ist bekannt, daß uteroplazentare Dopplermessungen bei lateralem Plazentasitz signifi-kante Seitendifferenzen aufweisen, und diese wiederum scheinen mit einer ungünstigen Prognose insbesondere infolge Präeklampsie belastet zu sein. Deshalb haben wir die Beziehung zwischen sonographischem späterer Manifestation prospektiv untersucht. Methode: 184 Patientinnen einem Gestationsalter 24 36 Wochen wurden untersucht Plazentalokalisation sonographisch als zentral oder lateral...
The mean duration of a normal pregnancy, calculated from the 1st day last menstrual period, is 280 days or 40 + 0 weeks gestation (GW). A pregnancy prolonged by more than 14 days, in other words, lasting 294 42 GW more, defined WHO and FIGO as prolonged, post-term post-mature pregnancy. period between 41 6 referred to late-term
Ziel dieser Arbeit ist es, die Anwendung des Cardiotokogramms (CTG) zur Überwachung ungeborenen Kindes auf der Basis evidenzbasierter Methoden zu standardisieren. Dies erfolgt unter Berücksichtigung Einflussfaktoren das CTG, Verwendung einheitlicher Definitionen und objektiver Bewertungsmöglichkeiten sowie durch Hinweise vorgeschaltete Diagnostik additive Überwachungsverfahren.
Antenatal stenosis or closure of the ductus arteriosus unrelated to either congenital heart defects prostaglandin inhibitors is considered be uncommon, but may result in congestive failure, hydrops fetalis, and perinatal death. We report a case idiopathic ductal detected prenatally by two-dimensional Doppler echocardiography fetus presenting atrial flutter right dilatation at 31 weeks gestation. Prenatal treatment with digoxin verapamil resulted conversion sinus rhythm. The was closely...
Increased pulse wave reflection in the fetal arterial system, illustrated by a second systolic peak (M-sign) middle cerebral artery (MCA) Doppler waveforms, allows interpretation of systemic vasoconstriction. Little is known about vascular regulation during spina bifida (fSB) repair. Therefore, aim this study was to analyze MCA-Doppler waveform changes before, during, and after fSB repair.31 pregnant women who underwent repair were included. Fetal waveforms prospectively analyzed repair,...
This study was undertaken to test the accuracy of formulas we recently developed for sonographic estimation weight very preterm fetuses. The were used determine estimated weights from prenatal data 62 premature infants born at 23–29 weeks gestation, < 1,400 g. mean absolute deviation actual birth 75.8 ± (SD) 68.5 g, percent +0.60% and 8.1 5.6%; 90.3% lay within 15% weight. model described represents an accurate method
Pulsatile cardiac action is an energy consuming process. During pulse wave (PW) travel to the periphery, reflection back LV occurs. The concept of condition number, WCN, provides evidence that consumption minimised when time return Tr takes a certain percentage cycle T. Our objective was assess WCN and timing Tr/T in human fetus. Based on relation: = HR×L/PWV, pulsatile optimised for 0.1 (HR: heart rate, L: effective aortic length, PWV: PW velocity; Pahlevan 2014, 2020). Rearranging with...
vertreten durch PD Dr. med. Guido Stichtenoth und Prof. Egbert Herting (Leitlinienkoordinatoren)
Homozygous alpha-thalassaemia Hb Bart is a very rare illness in North America and Western Europe, but common cause of NIHF especially South East Asia. It causes severe hydrops fetalis with lethal outcome maternal complications as preterm labour, pre-eclampsia retained placenta. A case report an immigrant from Laos labour fetal ascites, without signs demonstrated. Fetal heart rate (FHR) trace biophysical profile were pathological, while umbilical Doppler flow was normal due to hypoxaemia,...
We report on the circulatory changes of a severely growth-retarded fetus at 26 weeks gestation with intrauterine death after 6 days observation and birth weight 480 g. On admission already showed signs centralisation; furthermore, we found pulsation in umbilical vein diastolic reverse flow artery. During this increased compensatory phase fetal centralisation was followed last day by decompensation an apparently normal middle cerebral artery waveform, mimicking preterminal normalisation blood flow.