A5101100627- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular and exercise physiology
- Atrial Fibrillation Management and Outcomes
- Studies on Chitinases and Chitosanases
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Cardiac pacing and defibrillation studies
- Nuclear Receptors and Signaling
- Total Knee Arthroplasty Outcomes
- Physical Activity and Health
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Disease Prevention
- Circular RNAs in diseases
- Macrophage Migration Inhibitory Factor
- Biomarkers in Disease Mechanisms
- Bone Metabolism and Diseases
- Extracellular vesicles in disease
- GDF15 and Related Biomarkers
- Food Allergy and Anaphylaxis Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Nanjing Medical University
2009-2025
Jiangsu Province Hospital
2009-2025
Shanghai Normal University
2024
The Central Hospital of Shaoyang
2024
Anhui University of Finance and Economics
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2014
Peking Union Medical College Hospital
2014
United States Government Accountability Office
2014
To explore the clinical characteristics and risk factors for adverse outcomes in patients with Sjögren's Syndrome-associated pulmonary arterial hypertension (SS-PAH). A retrospective analysis was conducted on SS-PAH diagnosed by right heart catheterization (RHC) between March 2013 2024 across four Chinese medical centers. Patients were categorized into primary (pSS-PAH) overlap SS-PAH, based presence of additional autoimmune diseases. We compared demographic data, echocardiographic...
Connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) patients with left heart dysfunction may have worse prognosis. This study was to investigate the prognostic value of HFA-PEFF score in connective PAH. single-center retrospective cohort enrolled 147 CTD-PAH diagnosed via right catheterization (RHC), divided into two groups based on their scores: < 5 (n = 74) and ≥ 73). The clinical characteristics were compared between groups. primary end point all-cause...
Abstract Background Dermatomyositis (DM) is an acquired autoimmune disease that can cause damage to various organs, including the heart muscle. However, mechanisms underlying myocardial injury in DM are not yet fully understood. Methods In this study, we utilized publicly available datasets from Gene Expression Omnibus (GEO) database identify hub-genes enriched immune system process and myocarditis. Weighted gene co-expression network analysis (WGCNA), differentially expressed genes (DEGs)...
Introduction To explore whether blood flow-restrictive resistance exercise (BFRE) can be used as an alternative strategy to moderate-intensity training (RT) improve metabolic disorder and body composition in older adults with type 2 diabetes (T2DM). Methods This is a single-blind, randomized, controlled trial. Ninety-eight T2DM were randomly divided into three groups: BFRE group (n = 34), RT 31) control 33). Two groups received supervised collective for period of six months, each lasting 50...
Cardiac involvement is a serious complication of idiopathic inflammatory myopathy (IIM). GDF-15 can predict the risk and prognosis cardiovascular disease, but its value unclear in IIM.To investigate diagnostic for myocardial IIM.A total 77 IIM patients from May 2018 to August 2020 were included this retrospective study. Of these, 43 underwent cardiac magnetic resonance (CMR) examination. There 33 SLE 16 healthy people used as control group. The concentration these groups was measured by...
ABSTRACT Photoperiod/thermo‐sensitive genic male sterility (P/TGMS) is critical for rice two‐line hybrid system. Previous studies showed that slow development of pollen a general mechanism sterility‐to‐fertility conversion TGMS in Arabidopsis. However, whether this still exists unknown. Here, we identified novel line, ostms16 , which exhibits abnormal exine under high temperature and fertility restoration low temperature. In mutant, single base mutation OsTMS16 fatty acyl‐CoA reductase...
Velocity vector imaging (VVI) allows noninvasive measurement of left ventricular (LV) strain and rotation angle-independently. We investigated strain, myocardial synchrony when pacing at different sites in the right ventricle to determine which site yields most physiological pacing, as determined with VVI imaging.Thirty-one patients normal LV function referred for elective electrophysiology exam were used this study. Catheters (6F quadripolar) positioned atrium, apex, outflow tract, His...
Background Controversy still exists regarding whether medial parapatellar approach (MP) or midvastus (MV) is preferable in total knee arthroplasty (TKA) up to now. The aim of this meta-analysis was compare the clinical and radiological outcomes following MV MP for TKA. Methods A comprehensive search unrestricted-language literature all studies comparing with conducted through electronic databases PubMed, EMBASE, Cochrane Library, CNKI, VIP, WANFANG. Retrieval time from when were built...
Introduction The aim of this study was to investigate the effects blood flow-restrictive resistance training (BFR-RT) on improving metabolic abnormalities, pressure (BP), obesity, and 10-year atherosclerotic cardiovascular disease (ASCVD) risk in middle-aged patients with type 2 diabetes mellitus (T2DM). Method We conducted a parallel-group, single blind randomized controlled trial. Participants who met inclusion criteria were randomly divided into control group, BFR-RT group aerobic...
Heart failure (HF) complicating ST-segment elevation myocardial infarction (STEMI) is recognized as an ominous complication. The HAS-BLED and Outcomes Registry for Better Informed Treatment (ORBIT) scores are used to assess the bleeding risk in patients with anticoagulated atrial fibrillation. This study aimed investigate relationship of ORBIT Killip class 3-4 STEMI.639 STEMI were enrolled this study. recorded after admission, all divided into 2 groups: 1-2 groups. Different clinical...
Abstract Background Repetitive monomorphic ventricular tachycardia (RMVT) arising from the left His‐Purkinje system can occasionally be encountered during clinical practice. We describe eight cases as a unique entity in this study to characterize and electrophysiological features of patients. Methods Eight patients with frequent palpitation (five men median age 28 years) were included January 2003 July 2018. Twelve‐lead ECG (Electrocardiogram), Holter, echocardiographic tests performed after...
An osteoclast-associated receptor (OSCAR) is an immunoglobulin expressed in osteoclast, and takes part the formation of osteoclast. While soluble OSCAR (sOSCAR) component reported to be involved pathogenesis arteriosclerosis, aim this present study investigate relationship between sOSCAR acute coronary syndrome (ACS).This enrolled 41 patients with ACS 33 without as a control, from March 2017 June 2017. The baseline clinical parameters serum levels were collected participants. univariate...
Objective To evaluate the accuracy of systolic pressure variation (SPV) in monitoring blood volume patients.Methods Twenty-two ASA Ⅱ or Ⅲ patients (17 male,5 female),aged 49-79 yr,with body height 153-173 cm,weighing 55-89 kg,scheduled for elective coronary artery bypass grafting under cardiopulmonary bypass,were studied.Stroke (SVV) was monitored based on arterial wave and SPV measured invasive after changing title.After chest closed,the load test immediately carried out.6％ hydroxyethyl...
Objective To evaluate the accuracy and value of measurement left ventricular systolic function in dilated cardiomyopathy (DCM) hypertrophic (HCM) patients with stereo three-dimensional echocardiography (S3 DE). Methods End-diastolic volume (EDV), end-systolic (ESV),stroke volume(SV) ejection fraction(EF) ventricle were measured M-mode echocardiography(ME),two-dimensional echocardiography(2DE) S3DE DCM patientsC20 cases). HCM patients(20 cases),and normal controls(20 The different results...
Pulmonary arterial hypertension (PAH) is characterized by structural alterations of pulmonary vessels. Few studies have explored the clinical significance quantitative assessment small vessels chest computed tomography (CT). Our aim was to assess whether prognosis connective tissue diseases (CTD)-PAH patients could be assessed through measured CT.In all, 42 CTD-PAH diagnosed based on right heart catheterization were retrospectively investigated. All underwent a CT within 1 month before and...
Objective: To investigate the diagnostic value of serum chitinase-3-like-1 protein (YKL-40) levels for myocardial involvement in idiopathic inflammatory myopathy (IIM).Methods: A total 92 patients with definite IIM who visited Jiangsu Province People's Hospital between May 2018 and January 2022 were enrolled this retrospective study. Of these, 59 underwent cardiac magnetic resonance (CMR). Serum YKL-40 all participants was determined by ELISA.Results: 1. concentration significantly higher...