A5100437676- Nutrition and Health in Aging
- Frailty in Older Adults
- Education and Learning Interventions
- Odor and Emission Control Technologies
- Nutrition, Health and Food Behavior
- Industrial Gas Emission Control
- Health and Wellbeing Research
- Healthcare Education and Workforce Issues
- Food Quality and Safety Studies
- Diverse Approaches in Healthcare and Education Studies
- Body Composition Measurement Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Educational Systems and Policies
- Vehicle emissions and performance
- Health disparities and outcomes
- Mobile Ad Hoc Networks
- Educational Research and Pedagogy
- Systemic Lupus Erythematosus Research
- Psychosocial Factors Impacting Youth
- Education, Safety, and Science Studies
- Phytoestrogen effects and research
- Natural product bioactivities and synthesis
- Energy Efficient Wireless Sensor Networks
- Muscle Physiology and Disorders
University of Ulsan
2016-2025
Asan Medical Center
2016-2025
Ulsan College
2016-2025
Yonsei University
2016-2024
Gachon University Gil Medical Center
2024
Keimyung University
2012-2023
Catholic University of Korea
2004-2023
Korea Institute of Radiological and Medical Sciences
2023
Cornell University
2017-2023
Seoul National University
2018-2023
<h3>Objective</h3> Crohn9s disease (CD) is an intractable inflammatory bowel (IBD) of unknown cause. Recent meta-analysis the genome-wide association studies (GWAS) and Immunochip data identified 163 susceptibility loci to IBD in Caucasians, however there are limited other populations. <h3>Methods</h3> We performed a GWAS two validation Korean population comprising total 2311 patients with CD 2442 controls. <h3>Results</h3> confirmed four previously reported loci: <i>TNFSF15</i>,...
Frailty has been previously studied in Western countries and the urban Korean population; however, burden of frailty geriatric conditions aging populations rural communities had not yet determined.Thus, we established a populationbased prospective study adults aged ≥ 65 years residing Korea between October 2014 December 2014.All participants underwent comprehensive assessment that encompassed cognitive physical function, depression, nutrition, body composition using bioimpedance analysis.We...
South Korea became an aged society in 2017 and is predicted to become a super-aged by 2025. Therefore, knowing the trends among older adults identifying geriatric burden are crucial for both healthcare professionals policymakers. We previously summarized general health socioeconomic profiles of Korean from National Survey Living Conditions Welfare Needs Older Koreans. In this update, we briefly results 2020 Koreans categorizing them according their aging profile, status, lifestyle, status....
Pathophysiological background in different phenotypes of nonalcoholic fatty liver disease (NAFLD) remains to be elucidated. The aim was investigate the association between fecal and blood microbiota profiles presence NAFLD obese versus lean subjects. Demographic clinical data were reviewed 268 health checkup examinees, whose samples available for analysis. diagnosed with ultrasonography, subjects further categorized as (body mass index (BMI) ≥25) or (BMI <25). Fecal communities analyzed by...
Cyclin dependent kinase 1 (Cdk1) have previously reported correlation with cancer growth and a key regulator for cell cycle. Mostly, Cdk1's function of nucleus cycle is well known to be associated cancer, but cytoplasmic traits are not clearly identified, yet. We revealed that tissue microarray blocks epithelial ovarian (n = 249) showed increased level Cdk1 (p < 0.001), in 0.192) histologic type independently. On survival analysis, overexpression conferred significantly worse prognosis...
We aimed to describe the age- and sex-specific distributions of gait speed evaluate associations with longitudinal outcomes in Korean rural community-dwelling older adults.A total 1,348 people (mean age: 76 years, 55% women) population-based, prospective cohort Aging Study Pyeongchang Rural Area (ASPRA) between October 2014 June 2017. All participants underwent a comprehensive geriatric assessment, including 4-m usual speed, were followed annually.Among participants, women had slower than...
Abstract Background To determine the clinically meaningful changes and responsiveness of widely used frailty measures. Methods We analyzed data from a prospective cohort study 1,135 community-dwelling older adults who underwent assessments health-related quality life using EuroQol-5D at baseline 1 year later. Frailty measures included deficit-accumulation index (FI); phenotype; Fatigue, Resistance, Ambulation, Illness, Loss Weight scale; Study Osteoporotic Fracture (SOF) index. determined by...
Background: Community-dwelling older adults living in rural areas are a less favorable environment for health care compared with urban adults. We believe that intermittent coaching through wearable devices can help optimize medically limited environments. Objective: aimed to evaluate whether device and mobile-based or self-management could increase physical activity outcomes of small groups areas. Methods: To address the above evaluation goal, we carried out "Smart Walk" program, model...
The primary aim of this study was to evaluate the effectiveness a 6-month multicomponent intervention on physical function in socioeconomically vulnerable older adults rural communities. As secondary aims, we evaluated frailty and other geriatric syndromes, sustained benefit at 12 months, baseline characteristics associated with poor response.This designed-delay conducted 187 (mean age: 77 years; 75% women) who were living alone or low income three regions Korea. A 24-week program that...
South Korea is the fastest aging country in world, having become an aged society 2017, with over 14% of its population 65 years or older. This Korean Geriatrics Fact Sheet 2018 aimed to overview and clarify current geriatric burden trends Korea. Using nationwide surveys public reports from government related organizations, especially 2017 Survey Living Conditions Welfare Needs Older Persons Institute for Health Social Affairs, our committee has summarized profile, socioeconomic status,...
Population aging is a challenge, therefore efficient frailty screening has been increasingly emphasized for mass older populations. This study aimed to evaluate the prevalence of social and its association with physical frailty, geriatric syndromes activity daily living (ADL) disability in community-dwelling adults. A cross-sectional was conducted 408 adults (mean age, 75 years; 58% female) Aging Study PyeongChang Rural Area. five-item index administered (range: 0-5); (1) going out less...
Though bioelectrical impedance analysis (BIA) is a favorable tool for assessing body composition to estimate nutritional status and physical fitness, such as sarcopenia, there are accuracy issues. Hence, high-frequency (HF) BIA equipment uses an additional frequency of 2 3 MHz has been developed commercial model. However, no studies validating the safety HF-BIA. Therefore, this study aims assess validity HF-BIA in analyzing relative dual-energy X-ray absorptiometry (DEXA). Appendicular lean...
Sarcopenia, which is characterized by an age-related decline in muscle mass and function, poses significant challenges to geriatric care. Its definition has evolved from muscle-specific criteria include mass, physical performance, recognizing sarcopenia as a frailty. Sarcopenia associated with adverse outcomes, including mortality, falls, fractures, cognitive decline, admission long-term care facilities. Neuromechanical factors, protein-energy balance, protein synthesis-breakdown mechanisms...
Breathlessness shares aging mechanisms with frailty and sarcopenia.
It is important to define lean muscle mass when diagnosing sarcopenia, but there still controversy on the clinical implication of sarcopenia derived by height, weight, and body index (BMI) adjusted indices. We aimed evaluate longitudinal relevance 3 definitions in Korean population.We conducted comprehensive geriatric assessments for 1,379 community-dwelling older participants Aging Study PyeongChang Rural Area (ASPRA) cohort followed them up prospectively death, institutionalization,...
Abstract Background We aimed to assess the clinical characteristics of sarcopenia by original and revised European Working Group on Sarcopenia in Older People (EWGSOP 1 2), propose a new phenotype score (SPS) improve relevance outcomes. Methods Analyses were performed 1408 older adults Aging Study PyeongChang Rural Area, community‐based cohort Korea. For definitions, we used EWGSOP 1, 2, SPS, index counting number abnormal domains among components grip strength, gait speed, or muscle mass....
Background Home Internet of Things (IoT) services and devices have the potential to aid older adults people with disabilities in their living environments. IoT can also caregivers health care providers conveniently providing those need. However, real-world data on needs vulnerable are lacking. Objective The objective this study is conduct a face-to-face survey demand for among disabilities, caregivers, setting see if there any differences aspects Methods We conducted 500 participants between...
Multicomponent interventions improve physical function and frailty in older adults, but their long-term benefit remains uncertain.This prospective non-randomised study was conducted 383 Koreans (mean age, 76.8 years; female 72.3%) who were living alone or receiving medical aid. Of these, 187 individuals chose to receive a 24-week intervention that consisted of group exercise, nutritional supplements, depression management, deprescribing home hazard reduction. The remaining 196 received usual...