A5019328016- Congenital Heart Disease Studies
- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Blood transfusion and management
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Aortic Disease and Treatment Approaches
- Neonatal Respiratory Health Research
- Cardiac Arrhythmias and Treatments
- Respiratory viral infections research
- Cardiac and Coronary Surgery Techniques
- Cardiovascular and Diving-Related Complications
- Cardiovascular Conditions and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemodynamic Monitoring and Therapy
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Coronary Artery Anomalies
Nationwide Children's Hospital
2014-2024
The Ohio State University
2012-2024
The Ohio State University Wexner Medical Center
2023
Society of Thoracic Surgeons
2022
Monroe Carell Jr. Children's Hospital
2018
SUNY Upstate Medical University
2017
Georgia Regents Medical Center
2014
Nationwide Mutual Insurance Company (United States)
2012
University of Tübingen
2011
American Association for Thoracic Surgery
2011
Recent investigations at our institution have studied a variety of vasodilatory shock states that are characterized by vasopressin deficiency and pressor hypersensitivity to the exogenous hormone. Our experience in adults prompted use arginine-vasopressin (AVP) similar group critically ill children.This report describes early (from February 1997 through April 1998) 11 profoundly infants children (5 male, 6 female) ages 3 days 15 years (median, 35 days) treated with AVP for hypotension after...
We developed a tissue-engineered vascular graft (TEVG) for use in children and present results of U.S. Food Drug Administration (FDA)-approved clinical trial evaluating this patients with single-ventricle cardiac anomalies. The TEVG was used as Fontan conduit to connect the inferior vena cava pulmonary artery, but high incidence narrowing manifested within first 6 months, which treated successfully angioplasty. To elucidate mechanisms underlying early stenosis, we data-informed,...
Our goal was to evaluate the role of three anesthetic techniques in altering stress response children undergoing surgery for repair congenital heart diseases utilizing cardiopulmonary bypass setting fast tracking or early tracheal extubation. Furthermore, we wanted correlation between blunting and perioperative clinical outcomes.Prospective, randomized, double-blinded study.Single center from December 2008 May 2011.Forty-eight subjects (low-dose fentanyl plus placebo, n = 16; high-dose 17;...
Abstract Objectives: To report an institutional experience performing percutaneous atrial septal interventions in patients with hypoplastic left heart syndrome (HLHS). Background: The success of the Hybrid approach palliating HLHS is crucially dependant on relieving any significant interatrial restriction. Data transcatheter to relieve restrictions are limited. Methods: We retrospectively reviewed 67 that were performed between July 2002 and September 2007 56 HLHS. median weight was 3.35 kg....
Advances in surgical and medical management have greatly improved long-term survival rates patients with congenital heart disease (CHD). As these reach adulthood, myocardial dysfunction can occur, leading to cardiac transplantation.We reviewed the pretransplantation posttransplantation courses of 24 >18 years old (mean age, 26 years; range, 18 56 years) CHD who received a transplant between January 1985 September 1998. The relation preoperative perioperative risk factors for complications...
To identify risk factors for survival after cardiac retransplantation and compare the with that primary transplantation.A retrospective analysis of 952 patients undergoing transplantation treatment end-stage heart disease at a single center between 1977 October 1997. Of these, 43 (4.5%) underwent failure resulting from transplant-related coronary artery disease, rejection, early graft failure.No significant difference in actuarial patient was found by Kaplan-Meier 1, 2, 5 years those 76%,...
Early high-grade acute rejections (pathologic grade A2 or A3) in recipients of lung allografts are a major risk factor for the subsequent development obliterative bronchiolitis (OB). We analyzed factors 152 single (100) bilateral (52) transplanted at our institution between 1990 and 1996. Using Kaplan-Meier product limit estimate analysis, there was 50% probability A3 rejection by 1 yr after transplant. By univariate only significant predictor early presence one more mismatches HLA-DR locus...
Objective: To investigate the prevalence of necrotizing enterocolitis (NEC) in neonates undergoing Stage I hybrid procedure for palliation complex congenital heart disease (CHD). Neonates Norwood surgery hypoplastic left-heart syndrome have highest risk NEC all CHD patients. The is another palliative option syndrome, but this has not been reported. Design: Retrospective chart review 73 who underwent CHD. Demographic, perinatal, perioperative, clinical, and procedural data were collected. was...
The transfusion of blood products in the setting uncontrolled bleeding is unquestionably lifesaving. However, many instances, decision to transfuse based on physician gestalt rather than medical evidence. When indications for are unclear, benefits must be balanced against their significant risks and associated costs. As our institution a referral center patients Jehovah's Witness faith, this population has pushed development techniques achieve goal bloodless surgery. Our practices caring...
In recent years, the continuous noninvasive hemoglobin measurement has been offered by devices using advanced pulse oximetry technology. Accuracy established in healthy adults as well surgical and intensive care unit patients but not setting of acute hemorrhage. this study, we evaluated accuracy such a device clinical preoperative phlebotomy thereby mimicking scenario blood loss.This prospective study included undergoing repair congenital heart disease (CHD) for whom was planned. Blood...
The many advantages of early tracheal extubation following congenital cardiac surgery in young infants and children are now widely recognized. Benefits include avoiding the morbidity associated with prolonged intubation consequences sedation positive pressure ventilation setting altered cardiopulmonary physiology. Our practice operating room has evolved new challenges arena postoperative pain management have appeared.Review our institutional outcomes surgery.Inclusion criteria included all...