E. Berthoux
- Sarcoidosis and Beryllium Toxicity Research
- Systemic Lupus Erythematosus Research
- Venous Thromboembolism Diagnosis and Management
- Renal Diseases and Glomerulopathies
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Vasculitis and related conditions
- Pregnancy and Medication Impact
- Dermatological and COVID-19 studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- IgG4-Related and Inflammatory Diseases
- Systemic Sclerosis and Related Diseases
- Infectious Diseases and Tuberculosis
- Blood groups and transfusion
- Renal Transplantation Outcomes and Treatments
- Salivary Gland Disorders and Functions
- Cancer Immunotherapy and Biomarkers
- Chronic Lymphocytic Leukemia Research
- Blood disorders and treatments
- Drug-Induced Adverse Reactions
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Research on Leishmaniasis Studies
- Pericarditis and Cardiac Tamponade
- Oropharyngeal Anatomy and Pathologies
Centre Hospitalier Saint-Joseph Saint-Luc
2015-2024
Hôpital Saint Joseph
2023
Université Paris Cité
2022
Centre de Recherche Épidémiologie et Statistique
2022
Université Claude Bernard Lyon 1
2013-2022
Hôpital Edouard Herriot
2011-2022
Hospices Civils de Lyon
2011-2022
Hôpital de la Croix-Rousse
2022
Centre Hospitalier Universitaire de Saint-Étienne
2012
Hôpital Lyon Sud
2007-2011
There is little known about the impact of SARS-CoV-2 on patients with inflammatory rheumatic and musculoskeletal diseases (iRMD). We examined epidemiological characteristics associated severe disease, then death. also compared mortality between hospitalised for COVID-19 without iRMD.Individuals suspected iRMD-COVID-19 were included in this French cohort. Logistic regression models adjusted age sex used to estimate ORs 95% CIs COVID-19. The most significant clinically relevant factors...
Abstract Objectives The specific roles of remission status, lupus low disease activity state (LLDAS), and damage accrual on the prognosis pregnancies in women with SLE are unknown. We analysed their impact maternal flares adverse pregnancy outcomes (APOs). Methods evaluated all (≥18 years) enrolled prospective GR2 study an ongoing singleton at 12 weeks (one pregnancy/woman). Several sets criteria were used to define remission, damage. APOs included: foetal/neonatal death, placental...
Data about hydroxychloroquine (HCQ) levels during pregnancy are sparse. We assessed HCQ whole blood at first trimester of as a potential predictor maternal and obstetric/fetal outcomes in patients with systemic lupus erythematosus (SLE).
TNFα blockers have drastically improved rheumatoid arthritis prognosis by preventing joint destruction in DMARD resistant patients. Altering cytokine balance immune diseases may expose to paradoxical adverse events.We present the case of a 40-year-old woman, with confirmed erosive and seropositive RA, successfully treated blocker (etanercept) for seven years, who developed severe neurosarcoidosis. She had lymphocytic meningitis, bilateral peripheral facial paralysis anosmia, associated hilar...
The incidence of pulmonary embolism (PE) is high during severe Coronavirus Disease 2019 (COVID-19). We aimed to identify predictive and prognostic factors PE in non-ICU hospitalized COVID-19 patients. In the retrospective multicenter observational CLOTVID cohort, we enrolled patients with confirmed RT-PCR who were a medicine ward also underwent CT angiography for suspicion. Baseline data, laboratory biomarkers, treatments, outcomes collected. Predictive prognostics identified by using...
Abstract Background A high prevalence of pulmonary embolism (PE) has been described during COVID‐19. Our aim was to identify predictive factors PE in non‐ICU hospitalized COVID‐19 patients. Methods Data and outcomes were collected upon admission a French multicenter retrospective study, including patients for COVID‐19, with CT angiography (CTPA) performed the emergency department suspected PE. Predictive significantly associated identified through multivariate regression model. Results total...
Abstract Background Acid sphingomyelinase deficiency (ASMD) or Niemann–Pick disease types A, A/B, and B is a progressive, life-limiting, autosomal recessive disorder caused by sphingomyelin phosphodiesterase 1 ( SMPD1 ) gene mutations. There need to increase the understanding of morbidity mortality across children adults diagnosed with ASMD. Methods This observational retrospective survey analysed medical records patients ASMD retrievable data from 27 hospitals in France, diagnosed/followed...
To describe extra-haematological manifestations associated with human parvovirus B19 (HPV-B19) infection. We conducted a nationwide multicentre study to retrospectively the characteristics and outcome of in French adults. Data from 25 patients followed 2001 2016 were analysed. Median age was 37.9 years (range: 22.7–83.4), female predominance (sex ratio: 4/1). Only 3 had an underlying predisposing condition (hemoglobinopathy or pregnancy). The most common joint (80%) skin (60%) involvement....
<h3>Background and Objectives</h3> Spinal cord sarcoidosis is a rare manifestation of with consequent risk neurologic sequelae for the patient. We investigated prognostic factors efficacy immunosuppressive treatments in longitudinal cohort. <h3>Methods</h3> retrospectively studied patients spinal followed between 1995 2021 7 centers France. Patients definite, probable, or possible according to Neurosarcoidosis Consortium Consensus Group criteria involvement confirmed by MRI were included....
A 54-year-old male patient was admitted for acute respiratory distress with fever. He suffering from chronic sinusitis/rhinitis and had persistent otitis the past 2 months before admission despite several antibiotics courses. developed a complex pulmonary involvement (embolism diffuse alveolar hemorrhage) glomerular disease (proteinuria hematuria but initially no renal failure). Clinical suspicion of Wegener’s granulomatosis confirmed by positive high titer antineutrophil cytoplasmic...
Journal Article Accepted manuscript Comment on: Hydroxychloroquine levels in pregnancy and materno-fetal outcomes Systemic Lupus Erythematosus patients: Reply Get access Gelsomina Alle, MD, MD Service de Médecine Interne, Centre référence des maladies auto-immunes et auto-inflammatoires systémiques rares d'Ile-de-France, l'Est l'Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux Paris (AP-HP) - Université Cité. Paris, FranceRheumatology Section, Internal Medicine Service, Hospital Italiano...
The study was performed on 313 patients hospitalized in an acute geriatric unit during a six-month period and aimed at determine the prevalence of adverse drug events (ADE) preventability them. ADE were determined by medical information unit. Preventability inadequacy with standards care, medication-related factors (non respect contra-indication) explicit lists harmful medication elderly. 12.7%. mean age 84.8 years old. number comorbidities per patient 3 medications consumed 7.7±3.1. 70%...