A5052980210- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health, psychology, and well-being
- Sleep and Work-Related Fatigue
- Spaceflight effects on biology
- Climate Change and Health Impacts
- Musculoskeletal pain and rehabilitation
- Health and Conflict Studies
- Advanced Neuroimaging Techniques and Applications
- Occupational Health and Performance
- Health, Environment, Cognitive Aging
- Pesticide Exposure and Toxicity
- Myofascial pain diagnosis and treatment
- Complementary and Alternative Medicine Studies
- Dietary Effects on Health
- Acupuncture Treatment Research Studies
- Cholinesterase and Neurodegenerative Diseases
- Occupational Health and Safety Research
- Medical and Biological Ozone Research
- Geriatric Care and Nursing Homes
- Psychosomatic Disorders and Their Treatments
- Healthcare professionals’ stress and burnout
- Agriculture and Farm Safety
- Carcinogens and Genotoxicity Assessment
- Optimism, Hope, and Well-being
- Nutritional Studies and Diet
Baylor College of Medicine
2018-2024
Michael E. DeBakey VA Medical Center
2022
Boston University
2021
Baylor University
2011-2015
Centers for Disease Control and Prevention
1996-2011
Kansas State University
2005
National Center for Infectious Diseases
1997-1998
Analysis Group (United States)
1995
The University of Texas Health Science Center at Houston
1994
Gulf War veterans have reported health problems that they attribute to their military service, but little is understood about the nature or extent of these conditions. To determine whether Kansas are affected by excess problems, a population-based survey 1,548 who served in Persian (PGW) and 482 elsewhere (non-PGW) was conducted 1998. illness, defined as having chronic symptoms three six domains, occurred 34% PGW veterans, 12% non-PGW receiving vaccines during war, 4% did not receive...
At least one-fourth of U.S. veterans who served in the 1990-1991 Gulf War are affected by chronic symptomatic illness known as (GWI). Clear determination causes GWI has been hindered many factors, including limitations how epidemiologic studies have assessed impact complex deployment environment on veterans' health.We sought to address etiologic questions evaluating association with characteristics deployment.We compared veteran-reported wartime experiences a population-based sample 304...
Introduction Gulf War Illness (GWI), also called Chronic Multisymptom (CMI), is a multi-faceted condition that plagues an estimated 250,000 (GW) veterans. Symptoms of GWI/CMI include fatigue, pain, and cognitive dysfunction. We previously reported 12% convenience sample middle aged (median age 52 years) GW veterans met criteria for mild impairment (MCI), clinical syndrome most prevalent in older adults (e.g., ≥70 years). The current study sought to replicate extend this finding. Methods used...
An exploratory case-control study was conducted to assess whether the many reported differences in immune function of chronic fatigue syndrome (CFS) patients are detectable rigorously defined cases CFS. Although studies have between and controls various measures function, none these were found all studies. In this study, no white blood cell numbers; complex, complement, or serum immunoglobulin levels; delayed type hypersensitivity allergic responses; NK function; proliferative responses...
Epidemiologic studies have implicated wartime exposures to acetylcholinesterase (AChE)-inhibiting chemicals as etiologic factors in Gulf War illness (GWI), the multisymptom condition linked military service 1991 War. It is unclear, however, why some veterans developed GWI while others with similar did not. Genetic variants of enzyme butyrylcholinesterase (BChE) differ their capacity for metabolizing AChE-inhibiting chemicals, and may confer differences biological responses these compounds....
The Gulf War Illness Consortium (GWIC) was designed to identify objective biomarkers of (GWI) in 1991 veterans. symptoms GWI include fatigue, pain, cognitive problems, gastrointestinal, respiratory, and skin problems. Neurotoxicant exposures during deployment, such as pesticides, sarin, pyridostigmine bromide pills have been identified contributors GWI. We also found an association between mild traumatic brain injury (mTBI) increased rates However, the combined impact these physical chemical...
Abstract We performed serological testing for a large number of infectious agents in 26 patients from Atlanta who had chronic fatigue syndrome (CFS) and 50 controls matched by age, race, sex. did not find any agent associated with CFS. In addition, we elevated levels antibody to wide range examined. particular, titers herpesvirus, nor evidence enteroviral exposure this group patients.
The Boston University-based Gulf War Illness Consortium (GWIC) is a multidisciplinary initiative developed to provide detailed understanding of brain and immune alterations that underlie illness (GWI), the persistent multisymptom disorder associated with military service in 1990-1991 War. core GWIC case-control clinical study conducted in-depth evaluation 269 veterans (223 GWI cases, 46 controls) at three U.S. sites included assessments, imaging, neuropsychological testing, analyses broad...
To address gaps in understanding the pathophysiology of Gulf War Illness (GWI), VA Million Veteran Program (MVP) developed and implemented a survey to MVP enrollees who served U.S. military during 1990–1991 Persian (GW). Eligible Veterans were invited via mail complete assessing health conditions as well GW-specific deployment characteristics exposures. We evaluated representativeness this GW-era cohort relative broader population by comparing demographic, military, between respondents...
Veterans with difficult-to-diagnose conditions who receive care in the Department of Affairs (VA) healthcare system can be referred for evaluation at one three specialty VA War-Related Illness and Injury Study Centers (WRIISC). 1990−1991 Gulf War have long experienced excess rates chronic symptoms associated condition known as (GWI), hundreds evaluated WRIISC. Here we provide first report from a cohort 608 seen WRIISC completed questionnaires on (>6 months) consistent GWI well prominent...
Gulf War Illness (GWI), a chronic multisymptom illness with complex and uncertain etiology pathophysiology, is highly prevalent among veterans deployed to the 1990-1991 GW. We examined how GWI phenotypes varied by demographic military characteristics GW-era veterans. Data were from VA's Cooperative Studies Program 2006/Million Veteran (MVP) 029 cohort, Genomics of GWI. From June 2018 March 2019, 109,976 MVP enrollees (out total over 676,000) contacted participate in Survey. Of eligible...
Abstract Background During deployment, veterans of the 1991 Gulf War (GW) were exposed to multiple war-related toxicants. Roughly a third these continue exhibit neurotoxicant induced symptoms Illness (GWI), multi-faceted condition that includes fatigue, pain and cognitive decrements. When studied empirically, both deployed with exposures those who meet criteria for GWI are more likely show deficits in area neuropsychological functioning. Although studies have shown impairments small sample...
Objective: Gulf War Illness (GWI) is a debilitating multisymptom condition that affects nearly third of 1990–91 (GW) veterans. Symptoms include pain, fatigue, gastrointestinal issues, and cognitive decrements. Our work has shown GWI rates potential causes for symptoms vary between men women Studies have documented neuropsychological neuroimaging findings mostly in or combined sex datasets. Data are lacking veterans due to lack power repositories veteran samples. Methods: We characterized GW...
Objective: To study various risk factors previously reported to be associated with chronic fatigue syndrome (CFS). Design: Case-control study. Setting: Metropolitan Atlanta CFS surveillance registry consisting of physicians and clinics that evaluate patients fatiguing illness. Patients: Twenty-five identified from the Centers for Disease Control Prevention, site, were matched by race, sex, age two randomly selected controls. Cases further subgrouped type illness onset-sudden, occurring...
Gulf War illness (GWI) refers to the multitude of chronic health symptoms, spanning from fatigue, musculoskeletal pain, and neurological complaints respiratory, gastrointestinal, dermatologic symptoms experienced by about 250,000 GW veterans who served in 1991 (GW). Longitudinal studies showed that severity these often remain unchanged even years after GW, with GWI continue have poorer general increased medical conditions than their non-deployed counterparts. For better management treatment...