A5010989010- Gut microbiota and health
- Tryptophan and brain disorders
- Artificial Intelligence in Healthcare and Education
- Glycosylation and Glycoproteins Research
- IL-33, ST2, and ILC Pathways
- Biofuel production and bioconversion
- Monoclonal and Polyclonal Antibodies Research
- Enzyme Production and Characterization
- Extracellular vesicles in disease
- AI in Service Interactions
- Phagocytosis and Immune Regulation
- Immune responses and vaccinations
- Parasitic infections in humans and animals
- Polysaccharides and Plant Cell Walls
- Fungal Biology and Applications
- Hematopoietic Stem Cell Transplantation
- Immune cells in cancer
- High Altitude and Hypoxia
- T-cell and B-cell Immunology
- MicroRNA in disease regulation
- Wine Industry and Tourism
- Congenital Anomalies and Fetal Surgery
- Immune Cell Function and Interaction
- Studies on Chitinases and Chitosanases
- Helicobacter pylori-related gastroenterology studies
Macao Polytechnic University
2024-2025
China Agricultural University
2008-2021
Xuzhou Medical College
2018-2020
Rationale: Breast cancer preferentially develops osteolytic bone metastasis, which makes patients suffer from pain, fractures and spinal cord compression. Accumulating evidences have shown that exosomes play an irreplaceable role in pre-metastatic niche formation as a communication messenger. However, the function of secreted by breast cells remains incompletely understood metastasis cancer. Methods: Mouse xenograft models intravenous injection were applied for analyzing cell-derived vivo....
Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans animals. Neuroinflammation impairment have been associated with microbiota dysbiosis, through the gut-brain axis. Furthermore, microbiota-accessible carbohydrates (MACs) found dietary fiber are important shaping microbial ecosystem potential to improve gut-brain-axis. However, effects of MACs on cognition an obese condition not yet investigated. The present study aimed evaluate effect...
A high-fat (HF) diet is a major predisposing factor of neuroinflammation and cognitive deficits. Recently, changes in the gut microbiota have been associated with impairment, through gut-brain axis. Curdlan, bacterial polysaccharide widely used as food additive, has potential to alter composition improve However, effects curdlan against HF diet-induced decline not investigated. We aimed evaluate neuroprotective effect mechanism dietary supplementation obesity-associated observed mice fed...
Spaceflight leads to health risks including bone demineralization, skeletal muscle atrophy, cardiovascular dysfunction, and disorders of almost all physiologic systems. However, the impacts microgravity on blood lineage cells hematopoietic stem (HSCs) in vivo are largely unknown. In this study, we analyzed peripheral samples from 6 astronauts who had participated spaceflight missions found significant changes several cell populations at different time points. These dynamic alterations role...
Excretory-secretory products released by Echinococcus granulosus protoscoleces (EgPSC-ESPs) are well-known to regulate T cell responses. However, their direct influence on the differentiation of B subsets remains largely elusive. This study investigated effects EgPSC-ESPs IL-10-producing cells (B10), and explored possible role Toll-like receptor 2 (TLR-2) signaling in this process. In comparison phosphate buffered saline (PBS), exposed excretory–secretory (ESPs) generated higher percentages...
<title>Abstract</title> This study investigates the burgeoning interest in ChatGPT's role education, with a particular emphasis on its effects postgraduate students' English-speaking proficiency, topic previously explored mainly through theoretical lenses scant empirical evidence. The research aims to fill this gap by examining experiences and perceptions of Chinese students using ChatGPT for IELTS speaking practice. Employing mixed-methods approach, combines experimental engagement ChatGPT,...
The burgeoning integration of Artificial Intelligence (AI) technology within educational settings, particularly in personalized learning environments, has garnered significant interest. This paper delves into the perceptions and experiences undergraduate students Chinese universities concerning AI's application learning. study surveyed 48 undergraduates from a comprehensive university who had utilized generative AI, gathering their insights through semi-structured interviews. Thematic...
T cell factor 1 (Tcf1) is known as a critical mediator for natural killer (NK) development and terminal maturation. However, its essential targets precise mechanisms involved in early NK progenitors (NKP) are not well clarified. To investigate the role of Tcf1 cells at distinct developmental phases, we employed three kinds genetic mouse models, namely, Tcf7 fl/fl Vav Cre/+ , CD122 Ncr1 mice, respectively. Similar to germline knockout found notably diminished number defective BM from all...
Nano-antibodies possess great potential in many applications. However, they are naturally derived from heavy chain-only antibodies (HcAbs), which lack light chains and the CH1 domain only found camelids sharks. In this study, we investigated whether precise genetic removal of exon γ1 gene enabled production a functional IgG1 mice. chain dimers lacking associated were detected sera genetically modified modification led to decreased expression but increased other IgG subclasses. The mice...
Abstract This study delves into the retrospections of undergraduate students concerning their online learning experiences after COVID-19 pandemic, using nine key influencing factors: behavioral intention, instruction, engagement, interaction, motivation, self-efficacy, performance, satisfaction, and self-regulation. 46 Year 1 from a comprehensive university in China were asked to maintain reflective diaries throughout an academic semester, providing first-person perspectives on strengths...