- Vaccine Coverage and Hesitancy
- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
- Genetic Associations and Epidemiology
- Eating Disorders and Behaviors
- Electronic Health Records Systems
- Big Data and Business Intelligence
- Protease and Inhibitor Mechanisms
- Animal Vocal Communication and Behavior
- Autism Spectrum Disorder Research
- Sleep and Wakefulness Research
- Biomarkers in Disease Mechanisms
- BRCA gene mutations in cancer
- Acute Lymphoblastic Leukemia research
- Bone Metabolism and Diseases
- Global Educational Reforms and Inequalities
- Liver Disease Diagnosis and Treatment
- Music and Audio Processing
- Bone health and osteoporosis research
- Liver Disease and Transplantation
- Diverse Education Studies and Reforms
- Global Cancer Incidence and Screening
- Alcohol Consumption and Health Effects
- Parkinson's Disease Mechanisms and Treatments
- Genital Health and Disease
23andMe (United States)
2021-2024
Baylor College of Medicine
2024
Albert Einstein College of Medicine
2015
Da Nang Hospital
2006-2015
The University of Texas Medical Branch at Galveston
2006
Abstract Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency act prematurely and associated with multiple forms of psychopathology, including substance use disorders. We performed genome-wide association studies (GWAS) eight impulsive personality traits from Barratt Impulsiveness Scale short UPPS-P Impulsive Personality ( N = 123,509–133,517 23andMe research participants European ancestry), measure Drug Experimentation 130,684). Because these GWAS...
Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during REM sleep, is an early clinical symptom alpha-synucleinopathies and defines a more severe subtype. The genetic background RBD its underlying mechanisms are not well understood. Here, we perform genome-wide association study RBD, identifying five risk loci near SNCA, GBA, TMEM175, INPP5F, SCARB2. Expression analyses highlight SNCA-AS1 potentially SCARB2 differential expression in different brain regions with...
Alpha-1 antitrypsin deficiency (AATD) is an autosomal co-dominant condition that predisposes to emphysema, cirrhosis, panniculitis, and vasculitis. Underrecognition has prompted efforts enhance early detection testing of at-risk individuals. Direct-to-consumer (DTC) genetic represents additional method detection.
Purpose. Vietnamese women are at particular risk of osteoporosis and its complications. This study examined knowledge awareness among who have accessed health care. Methods. A sample 217 women, 13 to 76 years age, were attending 1 2 care facilities in Da Nang, Vietnam, between November December 2009 completed a questionnaire assessing their measuring using 30-item instrument reflecting 9 domains (eg, factors, diagnosis, prognosis). Results. majority (81.6%) the had heard osteoporosis....
Abstract Dyslexia is a learning difficulty with neurodevelopmental origins, manifesting as reduced accuracy and speed in reading spelling. It substantially heritable frequently co-occurs other conditions, particularly attention deficit-hyperactivity disorder (ADHD). Here, we investigate the genetic structure underlying dyslexia range of psychiatric traits using results from genome-wide association studies dyslexia, ADHD, autism, anorexia nervosa, anxiety, bipolar disorder, major depressive...
Physician recommendation is an important predictor of HPV vaccine acceptance; however, physician willingness and preferences regarding vaccination may be influenced by factors including patient age, type, cost. A cross-sectional survey was administered to a convenience sample health care providers in Da Nang, Vietnam, evaluate awareness, perceptions about vaccines, vaccinate female patient. Willingness evaluated using full-factorial presentation scenarios featuring the following factors:...
Abstract Sialyl-Lewis x (sLe , CD15s) is a tetra-saccharide on the surface of leukocytes required for E-selectin-mediated rolling, prerequisite to migrate out blood vessels. Here we show using flow cytometry that sLe expression basophils and mast cell progenitors depends fucosyltransferase 6 ( FUT6 ). Using genetic association data analysis qPCR, type-specific defect was associated with single nucleotide polymorphisms (SNPs) in gene region (tagged by rs17855739 rs778798), affecting coding...
Goals: We aimed to characterize risk factors for early versus advanced-stage early-onset colorectal cancer (eoCRC) at our safety-net hospital system. Background: Colorectal (CRC) is the third leading cause of cancer-related deaths in United States. Rates CRC diagnosis young adults (age below 50) have been rising despite an overall decrease CRC. this group often detected late due screening historically being persons 50 years and older. Etiologies increase rates eoCRC remain unclear, as do...
Abstract This study aimed to test theoretical predictions over biological underpinnings of previously documented phenotypic correlations between human language-related and musical rhythm traits. Here, after identifying significant genetic rhythm, dyslexia various traits, we adapted multivariate methods capture signals common genome-wide association studies ( N = 606,825) 1,138,870). The results revealed 16 pleiotropic loci P < 5 × 10 −8 ) jointly associated with impairment dyslexia,...
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...
Dinh, T.A.; Rosenthal, S.L.; Doan, E.D.; Pham, V.H.; Tran, B.D.; Trang, T.; V.D.; Phan, B.G.A.; Chu, H.H.K.; Breitkopf, C. Radecki Author Information