A5074036471- COVID-19 and healthcare impacts
- Global Health Care Issues
- Health disparities and outcomes
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Healthcare cost, quality, practices
- Inflammatory Bowel Disease
- Air Quality and Health Impacts
- Tuberculosis Research and Epidemiology
- Biosimilars and Bioanalytical Methods
- Migration, Health and Trauma
- Employment and Welfare Studies
- Stroke Rehabilitation and Recovery
- Artificial Intelligence in Healthcare and Education
- Melanoma and MAPK Pathways
- Maternal and Perinatal Health Interventions
- Preterm Birth and Chorioamnionitis
- Medical and Biological Sciences
- Ginkgo biloba and Cashew Applications
- Healthcare Systems and Public Health
- Health Systems, Economic Evaluations, Quality of Life
- Autopsy Techniques and Outcomes
- Rheumatoid Arthritis Research and Therapies
- RNA regulation and disease
- Economic and Financial Impacts of Cancer
Regione Siciliana
2021-2024
Regional Health
2022
To date, no population-based studies have specifically explored the external validity of pivotal randomized clinical trials (RCTs) biologics simultaneously for a broad spectrum immuno-mediated inflammatory diseases (IMIDs). The aims this study were, firstly, to compare patients' characteristics and median treatment duration approved IMIDs between RCTs' real-world setting (RW); secondly, assess extent biologic users treated in that would not been eligible inclusion into RCT each indication...
Earlier in 2020, seven Italian regions, which cover 62% of the population, set up Mimico-19 network to monitor side effects restrictive measures against Covid-19 on volumes and quality care. To this aim, we retrospectively analysed hospital discharges data, computing twelve indicators volume performance three clinical areas: cardiology, oncology, orthopaedics. Weekly for period January-July 2020 were compared with corresponding average 2018-2019; comparisons performed within 3 sub-periods:...
Cancer is a multifactorial disease. The large impact of occupational exposure on the burden cancer continues to be paramount public health concern that deserves more attention. study aims evaluate cancer-specific mortality risk in relation sectors employment. We used cohort from Rome Longitudinal Study (ROL) and linked it with National Social Insurance Agency (INPS) database obtain working histories. considered longest duration employment sector as proxy exposure, insurance activities...
Biological drugs have improved the management of immune-mediated inflammatory diseases (IMIDs) despite being associated with important safety issues such as immunogenicity, infections, and malignancies in real-world settings.The aim this study was to explore potential a large Italian multi-database distributed network for use postmarketing surveillance biological drugs, including biosimilars, patients IMID.A retrospective cohort conducted using 13 regional claims databases during 2010-2019....
Objectives To develop a population-based risk stratification model (COVID-19 Vulnerability Score) for predicting severe/fatal clinical manifestations of SARS-CoV-2 infection, using the multiple source information provided by healthcare utilisation databases Italian National Health Service. Design Retrospective observational cohort study. Setting Population-based study database from five regions. Participants Beneficiaries Service, aged 18–79 years, who had residentship in participating...
The pandemic may undermine the equity of access to and utilisation health services for conditions other than COVID-19. objective study is evaluate indirect impact COVID-19 lockdown measures on sociodemographic inequalities in healthcare seven Italian areas.
to quantify the variability of COVID-19 mortality from beginning pandemic mid-July 2021, in relation immigrant status and by Region period.observational incidence study.the study population consists residents at 2020 seven Regions (Piedmont, Lombardy, Veneto, Emilia-Romagna, Tuscany, Lazio, Sicily) aged <=74 years.absolute frequency deaths occurred subjects who tested positive for SARS-CoV-2, crude standardized rates (standard: Italian 2020), ratios (obtained using Poisson models),...
Background: Preterm birth is a major worldwide public health concern, being the leading cause of infant mortality. Understanding risk factors remains limited, and early identification women at high preterm an open challenge. Objective: The aim study was to develop validate novel pre-pregnancy score for delivery in nulliparous using information from Italian healthcare utilization databases. Study Design: Twenty-six variables independently able predict were selected, LASSO logistic regression,...
Stroke is the leading global cause of permanent disability and second dementia within first year event. Systematic quality improvement interventions such as Audit & Feedback (A&F) can monitor improve performance post-stroke care in conjunction with use indicators (QIs). The scientific literature shows limited studies on QIs design for poststroke rehabilitation. In Italy, National Outcomes Evaluation Programme (PNE) annually provides several concerning acute wards. On contrary, assessment...
to assess the potential of using longitudinal metropolitan studies (LMS) study association between long-term exposure air pollution and incidence acute coronary events stroke.
Background: In Italy, the incidence of cutaneous malignant melanoma is two-fold higher in north than south. This gradient might be associated with differences trends and disease surveillance. We compared time rates, mortality dermatologic office visit rates skin biopsy between Emilia-Romagna Region (northern Italy) Sicily (southern Italy). Methods: The cancer registries Parma, Modena, Ferrara Romagna (current population, 2,606,465) Catania-Messina-Enna, Siracusa Ragusa (2,775,019) provided...
to describe differences in the incidence of SARS-CoV-2 infections between Italians and foreigners residing seven Italian Regions during different phases pandemic by gender.retrospective observational study.all confirmed from 02.02. 2020 16.07.2021 under study were included. resident population calculated National Institute Statistics as 01.01.2020 was used calculate rates. The considered period is divided into 5 sub-periods (phases).number five crude rates citizenship (Italian vs foreign)....
Abstract The COVID-19 pandemic has a non-negligible indirect impact on hospital care pathways, which is important to estimate. To this aim, we set up the Mimico-19 network of seven Italian regions (62% population) representing different socio-demographic areas country with also burden epidemic. We retrospectively analysed regional discharges data, computing twelve indicators volumes and performance in three clinical areas: cardiology, oncology orthopaedics, including time-dependent pathways...
Population Medicine considers the following types of articles:• Research Papers -reports data from original research or secondary dataset analyses.• Review -comprehensive, authoritative, reviews within journal's scope.These include both systematic and narrative reviews.• Short Reports -brief reports research.• Policy Case Studies articles on policy development at a regional national level.• Study Protocols -articles describing protocol study.• Methodology -papers that present different...
Population Medicine considers the following types of articles:• Research Papers -reports data from original research or secondary dataset analyses.• Review -comprehensive, authoritative, reviews within journal's scope.These include both systematic and narrative reviews.• Short Reports -brief reports research.• Policy Case Studies articles on policy development at a regional national level.• Study Protocols -articles describing protocol study.• Methodology -papers that present different...
Bilateral traits in the human body are generally symmetric. A composite of deviations from this bilateral symmetry is known as fluctuating asymmetry (FA). Increased FA has been associated with negative health outcomes and developmental disorders used a measure instability (DI). In previous study our laboratory, was found to be significantly higher patients type 2 diabetes mellitus (DM2) than controls. This raised possibility that measures DI may predict susceptibility adult DM2. However,...
to evaluate and validate the adoption of an algorithm for identification cases congenital anomalies (CAs) improve performance Congenital Malformations Registry Sicily Region (Southern Italy).an was used identify on a sample hospital discharge records (SDO) with ICD-9-CM code between 740-759 any diagnoses within first year life, together healthy births equal 5% total same period. The identified were evaluated through clinical record analysis.the analysed composed 4,271 June 2013 December 2014...