A5100634748- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Voice and Speech Disorders
- RNA modifications and cancer
- Infant Health and Development
- Facial Nerve Paralysis Treatment and Research
- Oral microbiology and periodontitis research
- Dental Implant Techniques and Outcomes
- Sleep and related disorders
- dental development and anomalies
- Child and Adolescent Psychosocial and Emotional Development
- Obesity, Physical Activity, Diet
- Microbial Metabolic Engineering and Bioproduction
- Child Nutrition and Feeding Issues
- Enzyme Catalysis and Immobilization
- Escherichia coli research studies
- Child Development and Digital Technology
- Obstructive Sleep Apnea Research
- Impact of Technology on Adolescents
- Head and Neck Cancer Studies
- Nerve injury and regeneration
- Biochemical and biochemical processes
- Sinusitis and nasal conditions
- Orthodontics and Dentofacial Orthopedics
- Ear Surgery and Otitis Media
Cleveland Clinic
2023-2025
Anhui Medical University
2019-2024
Nankai University
2012-2024
Third Xiangya Hospital
2021-2024
Central South University
2021-2024
Cleveland Clinic Lerner College of Medicine
2024
National Health and Family Planning Commission
2020-2024
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2004-2023
Life Cycle Engineering (United States)
2023
Background Endoscopic sinus surgery (ESS) is a minimally invasive procedure indicated for medically refractory chronic sinusitis (CRS). As with any surgical procedure, there are potential risks and complications. Objective The purpose of this study to report skull base, orbital, hemorrhagic-associated complication rates following ESS. Methods A retrospective query on the TriNetX platform identified patients diagnosed CRS who subsequently underwent ESS in last 20 years. Outcomes analyses were...
Obstruction of the kidney may affect native or transplanted kidneys and results in injury scarring. Presented here is a model obstructive nephropathy induced by unilateral ureteric obstruction (UUO), which can either be irreversible (UUO) reversible (R-UUO). In UUO model, ureter obstructed for variable periods time order to induce increasingly severe renal inflammation interstitial fibrotic R-UUO hydronephrosis, tubular dilation inflammation. After suitable period then surgically reversed...
Although previous studies have shown that screen time (ST), fast foods (FFs) and sugar-sweetened beverages (SSBs) consumption are associated with depressive symptoms in adolescents, research on these associations Chinese adolescents is scarce. This study aimed to examine the association between ST, FFs, SSBs explore mediating effects of FFs ST symptoms.This school-based nationwide survey was carried out among 14,500 students four provinces China. The Children's Depression Inventory used...
The immune response of brain cells to invading bacteria in vivo and the mechanism used by pathogenic escape surveillance remain largely unknown. It is believed that microglia eliminate phagocytosis based on vitro data. Here we find a small percentage engulf neonatal meningitis-causing Escherichia coli (NMEC), but more are activated produce tumor necrosis factor alpha (TNFα), which activates astrocytes secrete complement component 3 (C3) involved anti-bacterial activity. To evade activity...
Swallowing disorders, or dysphagia, can lead to bolus aspiration in the airway, causing serious adverse health effects. Current clinical interventions for dysphagia are mainly empirical and often based on symptoms rather than etiology, of which a thorough understanding is still lacking. However, it challenging study swallowing process that involves sequential structural motions inaccessible standard visualization instruments. This proposed an vitro method visualize hydrodynamics identify...
Objectives/Hypothesis The superior laryngeal nerve (SLN) is the major sensory for upper larynx. Damage to this impacts successful swallowing. first aim of study was assess effect unilateral SLN lesion on threshold volume sufficient elicit swallowing in an intact pig model; defined radiographically as maximum bolus area visible lateral view. second determine if a difference existed between ipsilateral and contralateral function result loss, measured radiologic density fluid seen valleculae....
Abstract Background Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157) causes bloody diarrhea and hemolytic-uremic syndrome. EHEC O157 encounters varied microenvironments during infection, can efficiently adapt to these using the two-component system (TCS). Recently, a functional TCS, RstAB, has been implicated in regulation of virulence several bacterial pathogens. However, regulatory function RstAB is poorly understood. This study aimed at providing insights into global effects RstA on...
An O -glycosylation-competent chassis was tailored for sustainable biosynthesis of a polysaccharide-based glycoprotein by simultaneous conversion glucose and glycerol.
Abstract Understanding the mechanisms underlying dysphagia is crucial in devising effective, etiology-centered interventions. However, current clinical assessment and treatment of are still more symptom-focused due to our limited understanding sophisticated symptom-etiology associations causing swallowing disorders. This study aimed elucidate giving rise penetration flows into laryngeal vestibule that results aspirations with varying symptoms. Methods: Anatomically accurate, transparent...
Abstract Delayed graft function (DGF) is a frequently observed complication following kidney transplantation (KT). Our prior research revealed dynamic shifts in salivary microbiota post-KT with immediate (IGF), yet its behavior during DGF remains unexplored. Five recipients and 35 IGF were enrolled. Saliva samples collected the perioperative period, 16S rRNA gene sequencing was performed. The of IGFs changed significantly gradually stabilized recovery renal function. composition DGFs...
Infant mammalian feeding consists of rhythmic suck cycles and reflexive pharyngeal swallows. Although we know how oropharyngeal sensation influences the initiation frequency swallow cycles, role palatal is unknown. We implanted EMG electrodes into mylohyoid muscle, a muscle active during suckling, thyrohyoid swallowing, in eight infant pigs. Pigs were then bottle-fed while lateral videofluoroscopy was simultaneously recorded from electrodes. Two treatments administered prior to compared with...
Abnormal kinematics during swallowing can result in aspiration, which may become life threatening. We tested the role of palatal sensation motor control pharyngeal swallow infants.
Flagella contribute to the virulence of bacteria through chemotaxis, adhesion and invasion host surfaces. Flagellar phase variation is believed facilitate bacterial evasion immune response. In this study, flnA gene that encodes Escherichia coli H17 flagellin was examined by whole genome sequencing genetic deletion analysis. Unilateral flagellar has been reported in E. H3, H47 strains, although mechanism for strain not previously understood. Analysis variants indicated caused an ∼35 kb DNA...
To delineate the anomaly and frequency of their occurrence in a pig model, we reported topography vagus laryngeal branches compared differences with humans. Thirty sides cervical nerve 15 fresh cadavers ( Sus scrofa) were microdissected. We measured branch diameters lengths using Vernier caliper resolution 0.01 mm. Two patterns shown: 56.7% cranial (CLN) 43.3% without CLN. The length CLN not affected by side neck P > 0.05), but recurrent (RLN) nodose ganglion significantly different...