A5102486711- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- Cancer Immunotherapy and Biomarkers
- SARS-CoV-2 and COVID-19 Research
- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Phytochemical compounds biological activities
- Cytokine Signaling Pathways and Interactions
- SARS-CoV-2 detection and testing
- Orthopedic Surgery and Rehabilitation
- Inflammatory Biomarkers in Disease Prognosis
- Geochemistry and Geologic Mapping
- Geological and Geochemical Analysis
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Lung Cancer Research Studies
- Respiratory viral infections research
- High-pressure geophysics and materials
- Sesquiterpenes and Asteraceae Studies
- Tumors and Oncological Cases
- Bone and Joint Diseases
- Pineapple and bromelain studies
- Vascular Anomalies and Treatments
- Fullerene Chemistry and Applications
Wuhan Children's Hospital
2024
Huazhong University of Science and Technology
2009-2024
Lishui Central Hospital
2024
Wenzhou Medical University
2024
Hebei Medical University
2010-2023
Fourth Hospital of Hebei Medical University
2010-2023
Central South University
2000-2023
The First Hospital of Changsha
2017-2023
Xiangya Hospital Central South University
2023
Mengo Hospital
2023
Tuberculosis (TB) is the most common opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS) caused by human virus (HIV) and one of primary causes death from AIDS. The increased accessibility to highly active antiretroviral therapy (HAART) has significantly improved clinical outcome HIV infection. However, following ART, rapid restoration immune system leads reconstitution inflammatory (IRIS). Oxidative stress innate immunity play a role TB‑associated IRIS...
Colorectal cancer (CRC) is the third most common in world. The purpose of this study was to investigate role TNNT2 proliferation, migration and invasion CRC cells its expression tissues better understand regulatory CRC.Western blotting (WB) qPCR were used detect colorectal paracancerous tissues. CCK-8, colony formation, Transwell other experiments clarify cells. Changes TNNT2, EGFR HER2 mRNA transcription levels detected by SYBR Real-Time PCR assay, effects overexpression or knockdown on...
Abstract Background Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. Based on symptoms, COVID-19 cases can be classified as symptomatic or asymptomatic. However, there is limited information about the differences between patients with and without pneumonia. Our study aimed to further discuss spectrum clinical characteristics of asymptomatic Methods In China, all are hospitalized in designated hospitals...
Background: Recently, an increasing number of cases with transformation from lung adenocarcinoma to small cell cancer (SCLC) have been identified, but few studies investigated the clinical, pathological as well molecular characteristics these cases. This study aimed summarize and analyze features.
With the continuous generation of new variants severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pressure epidemic prevention and control continues to increase in China. Omicron with stronger infectiousness, immune escape ability repeated infection spread many countries regions around world a short period time. China has also successively reported cases imported infections. This study aims understand epidemiological characteristics variant via analyzing patients Hunan Province,...
Aim: To evaluate long-term outcome and prognostic factors of stage III esophageal cancer after definitive (chemo) radiotherapy using three dimensional conformal (3DCRT) or intensity-modulated (IMRT) techniques. Methods: Patients with T3N1M0/T4N0-1M0 squamous cell carcinoma (ESCC) treated from 2002 to 2016 in 10 Chinese medical centers were reviewed. Overall survival (OS) progression-free (PFS) rates calculated. Prognostic analyzed by Log-rank test multivariate Cox model. Results: Total 1,450...
Colorectal cancer (CRC) is the third most common worldwide. At present, there are limited effective biomarkers of CRC. The present study aimed to identify potential signatures associated with tumorigenesis and prognosis CRC using publicly available databases, further validate identified in cell lines. Identification differentially expressed mRNAs between paracancerous samples was conducted based on data from Cancer Genome Atlas (TCGA; 471 tumor 41 normal samples). Survival analysis performed...
Aims: The present study is to investigate the association between T790M status and clinical characteristics of patients with EGFR-sensitive advanced non-small cell lung cancer (NSCLC) who progressed initial epidermal growth factor receptor tyrosine kinase inhibitors (EGFRTKIs) administration. Methods: A total 167 mutations NSCLC had successful genetic tests EGFR-TKI treatment were included in this retrospectively. demographic these collected, which manifested as pathological type, metastasis...
To examine the survival benefit of definitive concurrent chemoradiotherapy (CCRT) compared to radiotherapy alone in patients with esophageal squamous cell carcinoma (ESCC) using a real-world patient population.This retrospective study included 2,762 ESCC across ten medical centers China from 2001 2017. A total 1,133 received and 815 were treated CCRT. The rates assessed by propensity-score matching (PSM) subgroup analysis.The baseline characteristics significantly different between two...
Introduction: The objective of this case report is to provide clinical evidence that acute infectious wrist arthritis in children can lead the rare condition carpal tunnel syndrome (ACTS). This article discusses detail characteristics complicating ACTS terms etiology, pathogenic bacteria, treatment modalities, and sequelae improve understanding disease. Patient concerns: A 10-year-old male child presented with a 15-day history swelling pain left forearm, wrist, hand. Diagnoses: Left-sided...
Background: To study the anti-cancer effect of isoalantolactone, a sesquiterpene lactoneisolated from roots Inula heleniumon human gynecologic cancer cells. Methods: A structure-activity relationship experiment was designed to identify functional moiety isoalantolactone for its significant activity. Five cell lines were treated with isoalantolactone. Cell proliferation determined by MTT assay in vitro and apoptosis flow cytometry. Results: We found strongly inhibited proliferationofHEC-1,...
Background To investigate the anticancer effects of limonoid compounds that were isolated and purified from Xylocarpus granatum fruits on human esophageal cancer (EC) cells. A structure‐activity relationship experiment was designed to identify functional moiety identified as being critical for its activity. Methods Eca109 cells cultured in RPMI1640 medium treated with compounds. Cell proliferation determined by MTT assay vitro. apoptosis analyzed flow cytometry after xylogranatin C. The...
Abstract Background: In December 2019, a cluster of coronavirus Disease 2019 (COVID-19) occurred in Wuhan, Hubei Province, China. With the advent Chinese Spring Festival, this disease spread rapidly throughout country. The information about clinical characteristics COVID-19 patients outside Wuhan is limited. Methods: All with confirmed were admitted to First Hospital Changsha City, designated hospital for assigned by City Government. and epidemiological characteristics, data laboratory,...
Background . COPD is a common clinical chronic airway inflammatory disease that occurs mostly in middle‐aged and older adults over the age of 40. The incidence increasing year by onset gradually becoming younger. Objective To observe effect teach‐back combined with king interaction on life patients obstructive pulmonary (COPD). Methods A total 100 admitted to our hospital from Jan 2021 2022 were retrospectively selected be divided into 50 cases control group observation according nursing...
Objective To evaluate the efficacy of salvage radiotherapy for supraclavicular lymph node metastasis (SLNM) after initial treatment in patients with esophageal cancer. Methods A total 117 SLNM radical resection cancer were enrolled as subjects from 2006 to 2012. All received three-dimensional 1.8-2.0 Gy per cycle, 5 cycles a week. The survival rates calculated using Kaplan-Meier method and analyzed log-rank test. Cox model was used multivariate analysis. Results The follow-up...