A5102966998- Mitochondrial Function and Pathology
- Muscle Physiology and Disorders
- Adipose Tissue and Metabolism
- Neurogenetic and Muscular Disorders Research
- Amyotrophic Lateral Sclerosis Research
- RNA Research and Splicing
- MicroRNA in disease regulation
- Fibroblast Growth Factor Research
- Circular RNAs in diseases
- RNA modifications and cancer
- Prenatal Screening and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Cancer-related molecular mechanisms research
- Organ Donation and Transplantation
- Liver Disease Diagnosis and Treatment
- Epilepsy research and treatment
- Hereditary Neurological Disorders
- Mesenchymal stem cell research
- Bladder and Urothelial Cancer Treatments
- Child Nutrition and Water Access
- Frailty in Older Adults
- Heme Oxygenase-1 and Carbon Monoxide
- Calpain Protease Function and Regulation
Chinese PLA General Hospital
2025
Chinese People's Liberation Army
2025
State Key Laboratory of Kidney Diseases
2025
Lanzhou University
2024
Lanzhou University Second Hospital
2024
Wuhan Union Hospital
2022
Peking University Shenzhen Hospital
2022
Sun Yat-sen University
2007-2018
The First Affiliated Hospital, Sun Yat-sen University
2007-2018
Bayer (Japan)
2018
Nutritional deficiencies remain significant public health issues in older populations globally. This study evaluates the burden, trends, and cross-country inequalities of four common nutritional (protein-energy malnutrition, iodine deficiency, vitamin A dietary iron deficiency) adults from 1990 to 2021. Age-standardised prevalence, disability-adjusted life years (DALYs), average annual percentage changes (AAPCs) these people aged ≥ 65 at global, regional, national levels were estimated...
Abstract Hepatic steatosis is associated with significant morbidity and mortality after liver resection transplantation. This study focuses on the role of autophagy in regulating sensitivity fatty livers to ischemia reperfusion (I/R) injury. Quantitative immunohistochemistry conducted human allograft biopsies showed that, reduction markers LC3 Beclin-1 at 1 h reperfusion, was correlated hepatic poor survival transplant recipients. In animal studies, western blotting confocal imaging analysis...
Background The epidemiology, diagnosis, and treatment of motor neuron disease (MND) in Chinese patients are ill known. Methods A registered study 461 MND was conducted across 10 facilities 7 cities from February 2009 to March 2010. Results Patients were classified as amyotrophic lateral sclerosis (ALS) (84.4%), progressive bulbar palsy (PBP) (4.1%), muscular atrophy (PMA) (10.4%), or primary (PLS) (0.9%). predominant men (men/women; 1.6:1.0). Mean onset age 52.6 years, with the highest...
To investigate the trends in epilepsy prevalence, incidence, mortality, and disability-adjusted life-years (DALYs) all ages, with risk factors for - associated death, from 1990 to 2021.
The regulatory mechanism of mammary gland development and lactation is important, as not only provides healthy milk for infants, but also health benefits to mothers. Circular RNAs (circRNAs) have recently received much attention, a few been functionally characterized. In the present study, structure expression profile rat Tc2n-derived circular RNA (cTc2n) was investigated by several protocols. cTc2n comprised exons10 11 Tc2ngeneandhad no poly(A)structure. significantly higher in than other...
Background: Impaired liver regeneration (LR) in fatty was a critical problem to be solved. Our previous study showed that activation of an enterohepatic signal, which ileal fibroblast growth factor (FGF) 15/19 hepatic FGFR4 (FGF15/19-FGFR4) signalling promoted and reduced lipid accumulation after hepatectomy wild type mice. However, the effect FGF15/19-FGFR4 pathway on is unclear. Methods: Ob/ob mice used as model two-thirds partial (PH) performed ob/ob Recombinant human FGF19 (rhFGF19)...
Background: Acute kidney injury is a critical complication following liver transplant and it was associated with patient mortality after the operation. Herein, we conduct retrospective study to investigate acute in using organs from donation cardiac death (DCD). Methods: Datas patients undergoing transplantation between July 2011 2013 who received DCD grafts (n=76) were reviewed. AKI but prior hospital discharge defined according RIFLE criteria: peak serum creatinine ≥2 times baseline level....
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China