A5063480274- Adipokines, Inflammation, and Metabolic Diseases
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Ferroptosis and cancer prognosis
- Metabolism, Diabetes, and Cancer
- Moyamoya disease diagnosis and treatment
- Neuroendocrine Tumor Research Advances
- Cancer Mechanisms and Therapy
- Organ Donation and Transplantation
- Bone health and treatments
- Cancer-related molecular mechanisms research
- Retinal Development and Disorders
- Sarcoma Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- RNA Interference and Gene Delivery
- Liver Disease and Transplantation
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Orthopedic Infections and Treatments
- Microscopic Colitis
- Tannin, Tannase and Anticancer Activities
- Organ Transplantation Techniques and Outcomes
- Inflammatory Bowel Disease
- Bladder and Urothelial Cancer Treatments
- Growth Hormone and Insulin-like Growth Factors
Hebei University
2024
Southern University of Science and Technology
2024
University of South China
2023
Xinjiang Medical University
2019
The First Affiliated Hospital, Sun Yat-sen University
2010-2017
Sun Yat-sen University
2010-2017
General Hospital of Shenyang Military Region
2010
Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and may involve fat-induced activation serine kinase cascade involving IKK-β. To test this hypothesis, we first examined insulin action signaling awake rats during hyperinsulinemic-euglycemic clamps after lipid infusion with or without pretreatment salicylate, known inhibitor Whole-body glucose uptake metabolism were estimated using [3-3H]glucose infusion, individual tissues was [1-14C]2-deoxyglucose injection clamp....
To monitor and measure dendritic shrinkage of retinal ganglion cells (RGCs) in a strain transgenic mice (Thy-1 YFP) that expresses yellow fluorescent proteins neurons under the control Thy-1 promoter.A total 125 RGCs from 16 eyes YFP were serially imaged with confocal scanning laser ophthalmoscope for 6 months after optic nerve crush. Quantitative analysis cell body area, axon diameter, field, number terminal branches, branch length, branching complexity, symmetry, distance disc was used to...
Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and may involve fat-induced activation serine kinase cascade involving IKK-β. To test this hypothesis, we first examined insulin action signaling awake rats during hyperinsulinemic-euglycemic clamps after lipid infusion with or without pretreatment salicylate, known inhibitor Whole-body glucose uptake metabolism were estimated using [3-3H]glucose infusion, individual tissues was [1-14C]2-deoxyglucose injection clamp....
BackgroundCurrently, there are few studies on immune-related prognostic analysis of hepatocellular carcinoma (HCC). Our aim was to establish an immune-correlated model for HCC.MethodsImmune-associated cells were obtained from the scRNA-seq dataset (GSE149614) HCC. Differentially expressed genes between normal and tumor immune-associated ImmPort database used identify differentially (IRDEGs). Subsequently, risk established in TCGA-LIHC cohort (n = 438) Cancer Genome Atlas (TCGA) by using...
We describe a modified stent-assisted coiling technique, named the semi-deployment in endovascular treatment of wide-neck aneurysms. Thirty-one consecutive patients with 31 wide-necked or fusiform intracranial aneurysms were treated technique. The technical feasibility procedure, procedure-related complications, angiographic results, clinical outcome and follow-up angiography evaluated. In every case, technique was successfully deployed. Immediate demonstrated complete occlusion 24 cases...
Abstract Background Bladder cancer (BLCA) is the most prevalent malignant neoplasm of urinary tract, and ranks seventh as frequent systemic in males. Dysregulation programmed cell death (PCD) has been implicated various stages progression, including tumorigenesis, invasion, metastasis. However, correlation between multiple PCD modes BLCA lacking. Thus, a risk prediction model was built based on 12 models to predict prognosis immunotherapy response patients with BLCA. Methods The RNA...
Cancer stem cells (CSCs) often exhibit high expression of the p38/MAPK signaling pathway during therapy, leading to therapeutic stress-induced cellular escape (TSCE) and presenting a significant barrier cancer treatment. Therefore, blocking stress CSCs or simultaneously targeting stress-escaping (TSCSCs) has become crucial strategy in therapy. However, lack specific markers for identifying TSCSCs greatly limited development effective treatments. cell membranes selective binding...
Metastasis poses the greatest threat to lives of individuals with prostate cancer. Therefore, it is imperative identify underlying mechanism driving metastasis. Doing so would facilitate detection new diagnostic biomarkers and advancement treatment options for patients.Metastasis-related modules were identified through weighted gene co-expression network analysis based on microarray GSE6919. Hub genes confirmed by quantitative real-time PCR across different cell lines clinic samples. Pivotal...
Background: Acute kidney injury is a critical complication following liver transplant and it was associated with patient mortality after the operation. Herein, we conduct retrospective study to investigate acute in using organs from donation cardiac death (DCD). Methods: Datas patients undergoing transplantation between July 2011 2013 who received DCD grafts (n=76) were reviewed. AKI but prior hospital discharge defined according RIFLE criteria: peak serum creatinine ≥2 times baseline level....
Background: Diffusion-weighted imaging (DWI) is a novel technique to evaluate bowel inflammation in Crohn's disease (CD). It remains unclear whether DWI could differentiate grades of activity and add the accuracy conventional magnetic resonance enterography (MRE) defining activity. We aimed assess for evaluating ileocolonic CD compared with MRE, using ileocolonoscopy as reference standard. Methods: This was an observational study patients who underwent both MRE DWI. The findings ileocolon...
Abstract Echinococcus granulosus (E. granulosus) is a small parasitic flat worm that would cause zoonosis named Cystic echinococcosis (CE), which leads to serious healthy and economic damage all over the world. To prevent spread of disease, vaccine against E. has become one most effective strategies nowadays. According previous research, Eg14-3-3 protein an important candidate antigen granulosus. Therefore, serval bioinformatics approaches were used analyze spatial structure linear B-cell...