A5074902825- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Central Venous Catheters and Hemodialysis
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Influenza Virus Research Studies
- Bacterial Identification and Susceptibility Testing
- HIV, Drug Use, Sexual Risk
- Immune Cell Function and Interaction
- Tuberculosis Research and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Hepatitis C virus research
- Antibiotic Use and Resistance
- Vaccine Coverage and Hesitancy
- Surgical site infection prevention
- Antibiotic Resistance in Bacteria
- Virology and Viral Diseases
- Bacillus and Francisella bacterial research
- Pneumonia and Respiratory Infections
- Poxvirus research and outbreaks
- Peripheral Neuropathies and Disorders
Hospital Regional de Alta Especialidad del Bajío
2011-2025
Universidad de Guanajuato
2013-2024
Secretaria de Salud
2024
Universidad de León
2016-2022
Instituto Tecnológico de León
2019
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2003-2015
Instituto Nacional de Salud Pública
2015
AbbVie (United States)
2015
Cornell University
2015
To compare the efficacy of efavirenz (EFV) vs lopinavir/ritonavir (LPV/r) in combination with azidothymidine/lamivudine antiretroviral therapy naive, HIV+ individuals presenting for care CD4 counts <200/mm.Prospective, randomized, open label, multicenter trial Mexico. HIV-infected subjects <200/mm were randomized to receive label EFV or LPV/r plus (fixed-dose combination) 48 weeks. Randomization was stratified by baseline cell count (< =100 >100/mm). The primary endpoint percentage patients...
ObjectivesTo study the prevalence, risk factors, outcome, and molecular epidemiology in patients with bacteremia caused by extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae (Kp) (cases), comparison a susceptible Kp (controls).MethodsThis was retrospective case–control including all episodes of for period 1993 to 2002 at referral hospital adults Mexico. ESBL production tested E-test. All isolates were typed pulsed field gel electrophoresis (PFGE). A subset underwent plasmid...
Antiretroviral therapies have proved life-saving in HIV infection, dramatically reducing morbidity and mortality.With longer survival, morbidities mortalities infection are increasingly similar to the associated with ageing.In treated risk of these is linked immune activation, inflammation coagulation indices.And persons failure restore circulating CD4 T cell numbers a greater as well heightened levels coagulation.The drivers incompletely defined could be related sustained low viral...
We studied the prevalence of HIV, syphilis, hepatitis B virus (HBV), and C (HCV) infection associated risk behaviors in prison state system Guanajuato, Mexico between September 2011 February 2012. Blood samples were drawn from adult inmates all State prisons who agreed to participate this cross-sectional study. Data on collected by using self-administered questionnaires. The HBV, HCV was 0.6% [95% confidence interval (CI) = 0.2–1.1], 0.7% (95% CI 0.4–1.0), 0.4 0.04–0.74), 4.8 3.6–5.9),...
To estimate the prevalence of HCV-infection and identify associated factors among inmates in State Prison System Guanajuato Mexico (Sep-2011 to Feb-2012).Cross-sectional, observational study 10 prisons (2011-2012). We offered HCV-testing applied audio computer-assisted self-interviews all adults imprisoned System. used a complex survey analysis distribution variables its corresponding 95% confidence intervals, taking into consideration expected cluster effect by common characteristics within...
The 2009-2010 influenza A (H1N1pdm09) pandemic caused substantial morbidity and mortality among young patients; however, estimates have been confounded by regional differences in eligibility criteria inclusion of selected populations. In 2013-2014, H1N1pdm09 became North America's dominant seasonal strain. Our objective was to compare the baseline characteristics, resources, treatments with outcomes critically ill patients Mexican Canadian hospitals 2014 using consistent...
Carbapenem-resistant Gram-negative bacilli (CR-GNB) are a major public health concern. We aimed to evaluate the prevalence of CR-GNB and frequency carbapenemase-encoding genes in tertiary referral center from El Bajio, Mexico. A cross-sectional study was conducted between January October 2022; (GNB) were screened for vitro resistance at least one carbapenem. further analyzed carbapenemase-production through phenotypical methods by real-time PCR following genes: blaKPC, blaGES, blaNDM,...
Background: People who live with HIV (PWLH) have been one of the most affected groups during current mpox outbreak. They are hypothesized to a more severe clinical course than people without but comparative data is scarce. We aimed compare features and outcomes in Mexico. Setting: Country-wide study Methods: performed an observational using nation-wide epidemiological data. included all confirmed diagnosed between May November 2022 Clinical sociodemographic characteristics were compared HIV....
Introduction of pneumococcal conjugate vaccines (PCV) targeted against a limited number serotypes substantially decreased invasive (IPD) and non-invasive diseases (NIPD) but it was accompanied by non-vaccine type replacement disease. After 9 years introduction PCV in Mexico, we analyze the evidence indirect effects on IPD NIPD serotype distribution among groups not to receive vaccine.From January 2000 December 2014, strains isolated from cases patients ≥5 age participant hospitals SIREVA II...
HIV pretreatment drug resistance (PDR) to NNRTIs in persons initiating ART is increasing Mexico.
Current results do not provide conclusive evidence on the effect of BCG vaccination COVID-19 alone or in combination with other factors. To address this limitation, study we used a citizen science initiative pandemic to collect data worldwide during 2 October 2020–30 2020 (1,233 individuals) structured way for analysing factors and characteristics affected individuals relation vaccination. For first time, our suggested that may increase risk at certain age, particularly vaccinated childhood....
We aimed to determine the effectiveness of switching bictegravir in maintaining an undetectable viral load (<50 copies/mL) among people with HIV (PWH) as compared continuing dolutegravir-, efavirenz-, or raltegravir-based antiretroviral therapy using nationwide observational data from Mexico. emulated 3 target trials comparing vs dolutegravir, efavirenz, raltegravir. Eligibility criteria were PWH aged ≥16 years a <50 copies/mL and at least months current (dolutegravir, raltegravir) between...
Summary Background Skin redness is a common cosmetic concern affecting predominantly fair‐skin individuals and often leading to rosacea. On the basis of current scientific knowledge physiological mechanisms underlying problem, complex integral skin care serum (100RXED2025) was developed tested clinically for efficacy. Method Forty‐five healthy men women volunteers, age 30–65, were recruited. All subjects had fair (phototype I, II, or III) presented some degree with telangiectasia on cheeks,...