A5100399062- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- RNA Research and Splicing
- Beetle Biology and Toxicology Studies
- Kruppel-like factors research
- Invertebrate Immune Response Mechanisms
- RNA modifications and cancer
- NF-κB Signaling Pathways
- Endometrial and Cervical Cancer Treatments
- Cancer, Lipids, and Metabolism
- RNA Interference and Gene Delivery
- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Botanical Studies and Applications
- Genetic diversity and population structure
- Phytoestrogen effects and research
- Antibiotic Resistance in Bacteria
- Ginger and Zingiberaceae research
- Cholesterol and Lipid Metabolism
- Immune Cell Function and Interaction
- Machine Learning in Bioinformatics
- Bacterial Identification and Susceptibility Testing
- Traditional Chinese Medicine Analysis
- Angiogenesis and VEGF in Cancer
Xijing Hospital
2025
Air Force Medical University
2025
Hunan Agricultural University
2023
First Affiliated Hospital of Soochow University
2020-2021
Qilu Hospital of Shandong University
2014-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2021
Soochow University
2020-2021
Louisiana State University Health Sciences Center New Orleans
2020
Pudong Medical Center
2020
Fudan University
2020
To evaluate the levels of miR-192-5p in non-alcoholic fatty liver disease (NAFLD) models and demonstrate role lipid accumulation.Thirty Sprague Dawley rats were randomly divided into three groups, which given a standard diet, high-fat diet (HFD), an HFD with injection liraglutide. At end 16 weeks, hepatic stearoyl-CoA desaturase 1 (SCD-1) measured. MiR-192-5p mimic inhibitor SCD-1 siRNA transfected Huh7 cells exposed to palmitic acid (PA). Lipid accumulation was evaluated by oil red O...
Background Beef cattle are among the most economically important animals in world because they farmed for their meat and leather. However, a lack of genetic information remains an obstacle to understanding mechanisms behind development this animal. Analysis beef transcriptome its expression profile data essential extending resources species would support studies on Results RNA sequencing was performed using Illumina High-Seq2000 platform. A total 25,605,140 26,214,800 reads were sequenced...
Growth is a priority trait from the point of view genetic improvement. Molecular markers linked to quantitative loci (QTL) have been regarded as useful for marker-assisted selection (MAS) in complex traits growth. Using an intermediate F2 cross slow and fast growth parents, linkage map Pacific whiteleg shrimp, Litopenaeus vannamei, based on amplified fragment length polymorphisms (AFLP) simple sequence repeats (SSR) was constructed. Meanwhile, QTL analysis performed growth-related traits....
The objective of this study was to evaluate the performance five commonly used automated antimicrobial susceptibility testing (AST) systems in China (Vitek 2, Phoenix, Microscan, TDR, and DL).Two "unknown" isolates, S1 (ESBL-producing Escherichia coli) S2 (KPC-producing Klebsiella pneumoniae), were sent 886 hospitals for identification AST. Using broth microdilution method (BMD) as gold standard, minimum inhibitory concentrations (MICs) determined.Most (392, 46.1%) Vitek followed by 16% each...
The growth and development of the Longissimus Dorsi muscle are complex, playing an important role in determination pork quality. study at mRNA level is particularly crucial for finding molecular approaches to improving meat quality pig breeding. current utilized transcriptome technology explore regulatory mechanisms intramuscular fat (IMF) deposition three core developmental stages (natal stage on day 1, growing 60, finishing 210) Ningxiang pigs. Our results revealed 441 differentially...
// Haiyang Guo 1,* , Xiyu Zhang Ruifen Dong 3 Xiaolin Liu Yinuo Li 2 Shan Lu Limei Xu Yuqiong Wang Xiyao Hou 1 Jian-Jun Wei 4 Changshun Shao and Zhaojian 1,2 Department of Molecular Medicine Genetics Ministry Education Key Laboratory Experimental Teratology,Shandong University, Jinan, Shandong, China Cell Biology, Shandong University School Medicine, Obstetrics Gynecology, Qilu Hospital, Pathology, Northwestern Chicago, IL,USA * These authors contributed equally to this work Correspondence:...
Ovarian carcinoma ranks fifth in the leading causes of cancer-relevant deaths among female, with highest fatality rate all gynecological malignant tumors and rising incidence worldwide. Mounting evidence has unveiled that lncRNAs are implicated tumorigenesis cancer develop ment. Several studies have proven carcinogenic role SNHG8 various malignancies, but physiological functions ovarian need more detailed explanations. The present study certified inhibition executed suppressive activities by...
Objective: Angiogenesis is involved in multiple biological processes, including atherosclerosis (AS) and cancer. Dickkopf1 (DKK1) plays many roles both tumors AS has emerged as a potential biomarker of cancer progression prognosis. Targeting DKK1 good choice for oncological treatments. Many anticancer therapies are associated with specific cardiovascular toxicity. However, the effects neutralizing therapy on unclear. We focused how affected angiogenesis ox-LDL-induced human umbilical vein...
MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play crucial regulatory roles in many biological processes, including the growth and development of skeletal muscle. miRNA-100-5p is often associated with tumor cell proliferation migration. This study aimed to uncover mechanism myogenesis. In our study, we found expression level was significantly higher muscle tissue than other tissues pigs. Functionally, this shows miR-100-5p overexpression promotes inhibits differentiation C2C12...
Abstract Acute coronary syndrome caused by the rupture of atherosclerotic plaques is one primary causes cerebrovascular and cardiovascular events. Neovascularization within plaque closely associated with its stability. Long non‐coding RNA (lncRNA) serves a crucial role in regulating vascular endothelial cells (VECs) proliferation angiogenesis. In this study, we identified lncRNA HCG11, which highly expressed patients vulnerable compared stable plaque. Then, functional experiments showed that...