A5007319414- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Recycling and Waste Management Techniques
- Mass Spectrometry Techniques and Applications
- Atmospheric chemistry and aerosols
- Vitamin D Research Studies
- Medical Imaging Techniques and Applications
- Analytical chemistry methods development
- Chemistry and Chemical Engineering
- Air Quality and Health Impacts
- Inorganic Fluorides and Related Compounds
- Environmental Impact and Sustainability
- Isotope Analysis in Ecology
- Forensic and Genetic Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Silicone and Siloxane Chemistry
- Carcinogens and Genotoxicity Assessment
- Health, Environment, Cognitive Aging
- Food Waste Reduction and Sustainability
- Atmospheric Ozone and Climate
- Carbon Dioxide Capture Technologies
- Pharmacological Effects and Assays
- Chemistry and Stereochemistry Studies
University of Copenhagen
2011-2025
European Environment Agency
2016-2023
German Environment Agency
2022
Santé Publique France
2022
Technical University of Denmark
2006-2019
Food Research Institute
2001-2016
Carleton College
1998
Systematic description of more than 200 uses PFAS and the individual substances associated with each them (over 1400 in total).
This commentary presents a scientific basis for managing as one chemical class the thousands of chemicals known PFAS (per- and polyfluoroalkyl substances). The includes perfluoroalkyl acids, perfluoroalkylether their precursors; fluoropolymers perfluoropolyethers; other PFAS. approach is presented in relation to physicochemical, environmental, toxicological properties. Specifically, high persistence, accumulation potential, and/or hazards (known potential) studied date warrant treating all...
Fluoropolymers are a group of polymers within the class per- and polyfluoroalkyl substances (PFAS). The objective this analysis is to evaluate evidence regarding environmental human health impacts fluoropolymers throughout their life cycle(s). Production some intimately linked use emissions legacy novel PFAS as polymer processing aids. There serious concerns toxicity adverse effects fluorinated aids on humans environment. A variety other PFAS, including monomers oligomers, emitted during...
In this discussion paper, the transition from long-chain poly- and perfluorinated alkyl substances (PFASs) to fluorinated alternatives is addressed. Long-chain PFASs include perfluoroalkyl carboxylic acids (PFCAs) with 7 or more carbons, sulfonic (PFSAs) 6 their precursors. Because have been found be persistent, bioaccumulative toxic, they are being replaced by a wide range of alternatives. We summarize key concerns about potential impacts on human health environment in order provide concise...
The concept of essential use is developed and applied to various uses PFASs determine the feasibility elimination or substitution in each category.
Per- and polyfluoroalkyl substances (PFAS) are of concern because their high persistence (or that degradation products) impacts on human environmental health known or can be deduced from some well-studied PFAS. Currently, many different PFAS (on the order several thousands) used in a wide range applications, there is no comprehensive source information individual functions applications. Here we provide broad overview use categories where have been employed for which function; also specify...
Despite decades of research on per- and polyfluoroalkyl substances (PFAS), fundamental obstacles remain to addressing worldwide contamination by these chemicals their associated impacts environmental quality health. Here, we propose six urgent questions relevant science, technology, policy that must be tackled address the "PFAS problem": (1) What are global production volumes PFAS, where PFAS used? (2) Where unknown hotspots in environment? (3) How can make measuring globally accessible? (4)...
Abstract Background The NORMAN Association ( https://www.norman-network.com/ ) initiated the Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/ in 2015, following collaborative trial on non-target screening of environmental water samples by mass spectrometry. Since then, this exchange information chemicals that are expected to occur environment, along with accompanying expert knowledge and references, has become a valuable base for “suspect screening” lists....
Abstract Background Safe and clean drinking water is essential for human life. Persistent, mobile toxic (PMT) substances and/or very persistent (vPvM) are an important group of which additional measures to protect resources may be needed avoid negative environmental health effects. PMT/vPvM do not sufficiently biodegrade in the environment, they can travel long distances with (those that PMT substances) environment health. substance research regulation arguably its infancy order get control...
Food contact articles (FCAs) are manufactured from food materials (FCMs) that include plastics, paper, metal, glass, and printing inks. Chemicals can migrate FCAs into during storage, processing, transportation. materials' safety is evaluated using chemical risk assessment (RA). Several challenges to the RA of exist.We review regulatory requirements for FCMs in United States Europe, identify gaps RA, highlight opportunities improving protection public health. We intend initiate a discussion...
Summary: Per- and polyfluoroalkyl substances (PFASs) are man-made chemicals that contain at least one perfluoroalkyl moiety, –CnF2n–. To date, over 4,000 unique PFASs have been used in technical applications consumer products, some of them detected globally human wildlife biomonitoring studies. Because their extraordinary persistence, environmental exposure to will be a long-term source concern. Some such as perfluorooctanoic acid (PFOA) perfluorooctanesulfonic (PFOS) investigated...
Per- and polyfluoroalkyl substances (PFAS) are a class of for which there widespread concerns about their extreme persistence in combination with toxic effects. It has been argued that PFAS should only be employed those uses necessary health or safety critical the functioning society where no alternatives available ("essential-use concept"). Implementing essential-use concept requires sufficient understanding current availability, suitability, hazardous properties alternatives. To illustrate...
Various countries have instituted risk governance measures to control and minimize the risks of chemicals at national international levels. Activities typically include assessment based on a) hazard exposure assessments; b) setting limits production, use, emissions chemicals; c) enforcement regulations; d) monitoring effectiveness taken. These steps largely depend chemical analysis access pure reference standards. However, except for specific highly regulated categories chemicals, such...
Summary Migration of chemicals from packaging materials to foods may lead human exposure. Polyfluoroalkyl substances ( PFAS ) can be used in technical mixtures TM s) for use food paper and board, have been detected serum umbilical cord blood. The specific structures the s are often unknown, but polyfluorinated alkyl phosphate esters PAP characterized s, packaging, food. metabolized into fluorotelomer alcohols FTOH perfluoroalkyl carboxylic acids PFCA s). Some endocrine activities,...
Due to large knowledge gaps in chemical composition and toxicological data for substances involved, paper board food-contact materials (P&B FCM) have been emerging as a FCM type of particular concern consumer safety. This study describes the development step-by-step strategy, including extraction, high-performance liquid chromatography (HPLC) fractionation, tentative identification relevant vitro testing selected tentatively identified substances. As case study, we used two fractions from...