A5101542924- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Autoimmune and Inflammatory Disorders Research
- Nutrition and Health in Aging
- Platelet Disorders and Treatments
- Viral-associated cancers and disorders
- Parvovirus B19 Infection Studies
- Immune Cell Function and Interaction
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lysosomal Storage Disorders Research
- Medical Imaging Techniques and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Blood groups and transfusion
- Ferroptosis and cancer prognosis
- Childhood Cancer Survivors' Quality of Life
- Telomeres, Telomerase, and Senescence
- Adolescent and Pediatric Healthcare
- Chronic Myeloid Leukemia Treatments
- Hematopoietic Stem Cell Transplantation
- Histiocytic Disorders and Treatments
- Cancer-related molecular mechanisms research
- Hepatitis B Virus Studies
- Calcium signaling and nucleotide metabolism
- Folate and B Vitamins Research
Hebei Provincial Center for Disease Control and Prevention
2025
Children's Hospital of Capital Institute of Pediatrics
2017-2024
Capital Institute of Pediatrics
2004-2024
Eastern Hepatobiliary Surgery Hospital
2023-2024
Second Military Medical University
2023-2024
Peking Union Medical College Hospital
2017-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2024
First Affiliated Hospital of Henan University of Science and Technology
2024
China Rehabilitation Research Center
2017-2021
The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
2021
To investigate the distribution of hantavirus (HV) in rodent organs, we selected eight counties across four regions Hebei Province (southern, northern, eastern, and central) as study areas. Rodents were captured using night trapping methods, organ samples aseptically collected for HV detection via quantitative real-time PCR (qPCR) gene sequencing. During 2022–2023 spring autumn seasons, 1386 rodents trapped, including 73 Rattus norvegicus carrying Seoul virus (SEOV). The highest rate was...
OBJECTIVE: To examine whether plasma fatty acid-binding protein 4 concentrations, measured in the first trimester, are associated with gestational diabetes mellitus (GDM). METHODS: This prospective, multicenter cohort study was conducted at three maternity centers two cities (Harbin and Beijing) China from July 2015 to June 2016. Data for fasting glucose concentrations trimester one-step GDM screening a 75-g oral tolerance test performed between 24 28 weeks of gestation were collected...
Objective . To investigate the preoperative body composition, metabolic characteristics, and postoperative changes in patients with active acromegaly analyze effects of gender age. Methods We included 36 untreated 37 nonfunctional pituitary adenomas. Adipose tissue (AT), visceral fat index (VFI), sclerotin, protein, skeletal muscle, total water (TBW), intracellular (ICW), extracellular (ECW) were measured using bioelectrical impedance analysis (BIA). Total energy expenditure (TEE) basal...
Phase angle (PhA), a bioimpedance parameter, is used to assess the nutrition status and body composition of patients. Patients with pancreatic head cancer often present changes that relate adverse outcomes. PhA may be useful evaluate prognosis in these patients, but data are deficient. We aim explore effects on evaluation short-term outcome prediction This prospective study included 49 participants who underwent pancreaticoduodenectomy (PD). All participants’ nutritional postoperative...
Abstract Background Several studies have demonstrated the prognostic utility of absolute lymphocyte count (ALC) during therapy for a range malignancies, with low ALC associated adverse outcome. Here we investigated whether retained independent significance respect to minimal residual disease (MRD) status in children acute lymphoblastic leukemia (ALL). Procedure We reviewed 171 cases pediatric ALL treated on Children's Oncology Group P9900 series treatment trials. Variables analyzed included...
Objective. Experimental and clinical studies have shown that obstructive jaundice results in increased intestinal permeability. The mechanisms implicated this phenomenon remain obscure. Integrated tight junctions (TJs) are essential for normal gut barrier function. TJ proteins, such as zonula occludens (ZO)-1, claudins occludin, indispensable to maintain the function of TJs. This study was undertaken investigate whether protein disruption occurs mucosa malignant (MOJ) patients. Material...
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignancy characterized by poor prognosis and closely linked to tumor stemness. However, the key molecules that regulate ICC stemness remain elusive. Although Y‐box binding protein 1 (YBX1) negatively affects in various cancers enhancing chemoresistance, its effect on cisplatin sensitivity remains unclear. Methods Three bulk single‐cell RNA‐seq datasets were analyzed investigate YBX1 expression association with...
Increasing evidence suggests an association between elevated serum aminotransferase levels and metabolic disorders (metabolic syndrome, hyperlipidemia diabetes mellitus). However, the significance of relatively low aminotransferases in relation to has not been fully investigated general population. We using data from a survey Jilin Province, China.In 2007, prospective was conducted throughout Jilin, China, covering both urban rural areas. A total 3835 people, 18-79 years old, were undergoing...
In this study, the influences of mulberry leaf extract (MLE) addition on physicochemical properties including specific volume, texture and sensory features white bread (WB) were evaluated by analysis technology. A double-blind, randomised, repeat-measure design was used to study impact MLE postprandial blood glucose response as well satiety index WB. Results showed that no significant effects WB except for slight changes color bitterness. The significantly reduced total rise after ingestion...
Tumor resection is the first-line therapy for acromegaly patients. In some cases, unsatisfactory intraoperative neuromuscular blockades (NMBs) lead to failed operations. The purpose of this study was investigate and quantify NMB status patients explore relationship between hormone levels body composition. Twenty with untreated seventeen nonfunctioning pituitary adenomas as controls were enrolled in study. assessed using train-of-four (TOF) technique TOF-Watch® SX. onset time NMB, deep...
Abstract Background Malnutrition is common in cancer patients. The NUTRISCORE a newly developed cancer-specific nutritional screening tool and was validated by comparison with the Patient-Generated Subjective Global Assessment (PG-SGA) Screening Tool (MST) Spain. We aimed to evaluate performance of NUTRISCORE, MST, PG-SGA estimating risk malnutrition Chinese Methods Data from an open parallel multicenter cross-sectional study 29 clinical teaching hospitals 14 cities were used. Cancer...
To investigate the efficacy and safety of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) in combination ATG post-transplant cyclophosphamide (PTCy) -induced immune tolerance after treatment childhood myelodysplastic syndromes(MDS）.From July 2016 to November 2020, a total 8 children with MDS receiving allo-HSCT combined PTCy-induced our hospital were enrolled, whose clinical data retrospected analyzed.Median age at diagnosis (1 male 7 females) was 6.4 (range, 10 months 15...
Objective Thrombocytopenic hemorrhage is one of the major appearance in pediatric hemorrhagic diseases, which, idiopathic thrombocytopenic purpura ( ITP ) most common disease. Thrombocytopenia earliest phenomenon or only certain phases such as ITP, aplastic anemia AA and myelodysplastic syndrome MDS ). By now, pathogenesis thrombocytopenia different diseases has not been clearly determined. At present, it very difficult to diagnose these estimate their prognosis with current clinical data....
The pathologic responses to transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC) are heterogeneous and result disparate outcomes. study aimed establish validate an effective nomogram for predicting complete response (PCR) after TACE.We analyzed the clinicopathologic characteristics of HCC undergoing hepatectomy following TACE. Variables statistical significance a multivariate logistic regression analysis were incorporated nomogram.We detected PCR 64 (50.4%)...
The experiment results of double dielectric barrier discharge reactor (DDBD) and pulsed corona (PCD) show that the optimal operating frequency DDBD is 10kHz, power 0.5~2.1kW, but PCD 1600Hz, 1~4.8kW. more suitable for deodorization device because wider voltage, it's easy to control electric field intensity in appropriate value, better adapt working environment. activated carbon adsorption was set at tail applied sewage pumping station, effect obtained. Ozone escape controlled prescribed...