Xiaona Zhang

ORCID: 0000-0001-6479-3562
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About
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Research Areas
  • Cryptography and Data Security
  • Sperm and Testicular Function
  • Cancer-related molecular mechanisms research
  • Reproductive Biology and Fertility
  • Coding theory and cryptography
  • Epigenetics and DNA Methylation
  • Virus-based gene therapy research
  • ZnO doping and properties
  • Cryptography and Residue Arithmetic
  • CAR-T cell therapy research
  • Diabetes and associated disorders
  • 2D Materials and Applications
  • Subtitles and Audiovisual Media
  • Cancer Research and Treatments
  • Semiconductor materials and interfaces
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • COVID-19 and Mental Health
  • Genetic and Kidney Cyst Diseases
  • Birth, Development, and Health
  • RNA modifications and cancer
  • Heusler alloys: electronic and magnetic properties
  • Biomedical Research and Pathophysiology
  • RNA Research and Splicing
  • Genetics, Aging, and Longevity in Model Organisms
  • Microstructure and mechanical properties

Xinjiang Institute of Ecology and Geography
2020-2024

Chinese Academy of Sciences
2008-2024

Beijing Technology and Business University
2024

China Pharmaceutical University
2024

Tianjin Medical University General Hospital
2024

University of Chinese Academy of Sciences
2017-2023

Beijing University of Technology
2008-2023

Chinese Academy of Agricultural Sciences
2023

Northeast Agricultural University
2023

Soochow University
2023

MoS2 on polycrystalline metal substrates emerges as an intriguing growth system compared to that insulating due its direct application electrocatalyst in hydrogen evolution. However, the is still indistinct with regard effects of inevitably evolved facets. Herein, we demonstrate for first time crystallography Au foil can mediate a strong effect monolayer MoS2, where large-domain single-crystal triangles are more preferentially Au(100) and Au(110) facets than Au(111) at relative high...

10.1021/acsnano.5b00081 article EN ACS Nano 2015-03-24

Resource7 March 2022Open Access Transparent process Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans Xueqing Wang orcid.org/0000-0003-3136-2568 State Key Laboratory of Cell Biology, Shanghai Institute Biochemistry and Center for Excellence Molecular Science, Chinese Academy Sciences, Shanghai, China University Beijing, Contribution: Resources, Data curation, Formal analysis, Validation, ​Investigation, Visualization, Methodology, Writing - original draft,...

10.15252/embj.2021109633 article EN cc-by-nc-nd The EMBO Journal 2022-03-07

Individual single-crystalline Si nanowires (NWs) were bent by forming loops or arcs with different radius. Positional-resolved atomic level strain distribution (PRALSD) along both of the radial and axial directions calculated mapped directly from atomic-resolution strained high-resolution electron microscopy (HREM) images NWs. For first time, neutral-strain axis shifted compressive zone to tensile region was demonstrated PRALSD direction. Bending-induced ripple-buckling NW observed a...

10.1021/nl9012425 article EN Nano Letters 2009-05-22

Background/Aims: Novel long non-coding RNA Fer-1-like protein 4 (FER1L4) has been reported to play crucial regulatory roles in tumor progression. However, its clinical significance and biological role osteosarcoma (OS) is completely unknown. The aim of the present study was investigate FER1L4 OS progression underlying mechanism. Methods: We analyzed expression levels tissues patients cell lines via quantitative RT-PCR (qRT-PCR). effect on proliferation, colony formation, migration invasion...

10.1159/000495554 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2018-01-01

Sertoli cells are the major component of spermatogonial stem cell (SSC) niche; however, regulatory mechanisms in that dictate SSC fate decisions remain largely unknown. Here we revealed features N6-methyladenosine (m6A) mRNA modification and demonstrated functions WTAP, key subunit m6A methyltransferase complex spermatogenesis. m6A-sequencing analysis identified 21,909 sites from 15,365 putative m6A-enriched transcripts within 6,122 genes, including many cell-specific genes. Conditional...

10.1016/j.stemcr.2020.09.001 article EN cc-by-nc-nd Stem Cell Reports 2020-10-01

An easy fabrication method comprising a slit die extrusion-hot stretch-quench process was used to make carbon nanotubes (CNTs) filled with anisotropically conductive polymer composite (ACPC). CNTs were first premixed polycarbonate (PC) by coagulation and then melt mixed polyethylene (PE). During extrusion, the CNT/PC/PE subjected hot stretching CNT/PC phase form in situ an oriented fibril assembly PE matrix. Finally aligned short fibrils quenched preserve their structure. The resultant...

10.1021/jp9042396 article EN The Journal of Physical Chemistry B 2009-12-23

Dysfunctional autophagy often occurs during the development of neurodegenerative diseases, such as Parkinson's disease, Huntington's and Alzheimer's disease. The purinergic P2X4 receptor is an ATP-gated ion channel that widely expressed in microglia, astrocytes, neurons central peripheral nervous systems. P2X4R involved regulation cellular excitability, synaptic transmission, neuroinflammation. However, role played by disease remains poorly understood. Rat models were established injecting...

10.4103/1673-5374.313053 article EN cc-by-nc-sa Neural Regeneration Research 2021-01-01

Background: The coronavirus disease 2019 (COVID-19) pandemic in China is essentially under control. Under global scrutiny, has started reviving the social, cultural, and working lives of its inhabitants. However, localized outbreaks COVID-19 are occurring, indicating that country still needs to follow prevention control measures. Previous studies have assessed knowledge, attitudes, behaviors general public regarding during pandemic. little known about practices (KAP) Chinese residents after...

10.3389/fpubh.2021.659797 article EN cc-by Frontiers in Public Health 2021-05-20

Abstract Leydig cells are essential components of testicular interstitial tissue and serve as a primary source androgen in males. A functional deficiency often causes severe reproductive disorders; however, the transcriptional programs underlying fate decisions steroidogenesis these have not been fully defined. In this study, we report that homeodomain transcription factor PBX1 is master regulator cell differentiation testosterone production mice. was highly expressed peritubular myoid adult...

10.1007/s00018-024-05249-5 article EN cc-by Cellular and Molecular Life Sciences 2024-05-09

CP/CuO x with suitable copper valence states obtained by fine-tuning the conductivity of electrochemical reconstruction may provide a competitive cathode catalyst for achieving excellent activity and selectivity NO 3 − -to-NH conversion.

10.1039/d4nr01625d article EN Nanoscale 2024-01-01

Purpose: Chronic wounds that are difficult to heal pose a major challenge for clinicians and researchers. Currently, common treatment methods focus on isolating the wound from outside world, relying tissue at site grow unaided. Umbilical cord mesenchymal stem cell (MSC) exosomes can promote healing by enhancing new blood vessel growth site. Valproic acid (VPA) reduces inflammatory response acts macrophages accelerate closure. In this study, VPA was loaded into umbilical MSC form drug carrier...

10.3390/molecules29174281 article EN cc-by Molecules 2024-09-09

Sertoli cells play indispensable roles in spermatogenesis by providing the advanced germ with structural, nutritional, and regulatory support. Lactate is regarded as an essential Sertoli-cell-derived energy metabolite that nurses various types of spermatogenic cells; however, this assumption has not been tested using genetic approaches. Here, we have reported depletion lactate production conditionally deleting dehydrogenase A (Ldha) greatly affected spermatogenesis. Ldha deletion...

10.3390/biology11121791 article EN cc-by Biology 2022-12-09

Abstract Sensory perception and metabolic homeostasis are known to deteriorate with ageing, impairing the health of aged animals, while mechanisms underlying their deterioration remain poorly understood. The potential interplay between declining sensory impaired metabolism during ageing is also barely explored. Here, we report that intraflagellar transport (IFT) in cilia neurons nematode Caenorhabditis elegans due a daf-19 /RFX-modulated decrease IFT components. We find reduced thus impairs...

10.1038/s41467-021-22065-8 article EN cc-by Nature Communications 2021-03-19

Fowl adenovirus serotype 8b (FAdV-8b), as causative agent of inclusion body hepatitis (IBH), poses a great threat to the poultry industry. Considering importance innate immune response in host against viral infections, we investigated pathogenicity FAdV-8b strain HLJ/151129 1-mo-old specific pathogen-free (SPF) chickens and responses infection this study. The results demonstrated that no obvious clinical signs were observed infected birds. Neither mobility nor mortality was both control...

10.1016/j.psj.2023.102846 article EN cc-by-nc-nd Poultry Science 2023-06-05
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