A5100354601- Spine and Intervertebral Disc Pathology
- Bone Tissue Engineering Materials
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Orthopaedic implants and arthroplasty
- Medical Imaging and Analysis
- Dental Implant Techniques and Outcomes
- Bone Metabolism and Diseases
- Bone health and osteoporosis research
- Thyroid Cancer Diagnosis and Treatment
- Periodontal Regeneration and Treatments
- Cardiac Imaging and Diagnostics
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Diabetes Treatment and Management
- Tissue Engineering and Regenerative Medicine
- Anesthesia and Pain Management
- Electrospun Nanofibers in Biomedical Applications
- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Graphene and Nanomaterials Applications
- Mechanical Circulatory Support Devices
- Esophageal Cancer Research and Treatment
- Menopause: Health Impacts and Treatments
- Spinal Hematomas and Complications
Xijing Hospital
2016-2025
Air Force Medical University
2016-2025
China Aerospace Science and Industry Corporation (China)
2023-2024
Capital Medical University
2019-2024
Northwest Normal University
2024
Beijing Anzhen Hospital
2023-2024
University of Hong Kong
2023-2024
Liaocheng People's Hospital
2011-2024
Shandong First Medical University
2024
Institute of Process Engineering
2024
Aims: To evaluate HAb18G/CD147 as a cancer‐associated biomarker using its monoclonal antibody HAb18. Methods and results: On immunohistochemical analysis of 28 tissue microarrays pathological sections 1117 breast samples, was expressed in carcinoma with an overall positivity rate 67.76%, which significantly higher than that sarcomas (27.34%, P < 0.0001) normal epithelial (5.18%, fetal (2.67%, tissues. In tissues from 14 organs, the difference expression between epithelium corresponding...
Osteomyelitis, particularly chronic osteomyelitis, remains a major challenge for orthopedic surgeons. The traditional treatment which involves antibiotics and debridement, does not provide complete solution infection bone repair. Antibiotics such as vancomycin (VCM) are commonly used to treat osteomyelitis in clinical settings. VCM use is limited by lack of effective delivery methods that sustained, high doses entirely fill irregular tissue infections.We engineered chitosan (CS)-based...
Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication. Meplazumab is humanized IgG
Efficient induction of antimicrobial activity with vancomycin nanoparticle-loaded poly(trimethylene carbonate) localized drug delivery system Yang Zhang,1,* Ruo-jia Liang,2,* Jiao-jiao Xu,3 Li-feng Shen,1 Jian-qing Gao,4 Xu-ping Wang,1 Na-ni Dan Shou,1 Ying Hu3 1Department Medicine, Zhejiang Academy Traditional Chinese 2Department Gynaecology, Provincial Hospital Hangzhou, 3Zhejiang Pharmaceutical College, Ningbo, 4College Sciences, University, People’s Republic China *These authors...
ABSTRACT Purpose The biomechanics of a novel facet joint fusion device is unknown. objective this study to analyze and compare the biomechanical properties integrated with oblique lateral interbody (OLIF) those conventional pedicle screw fixation device, employing finite element analysis. Methods A comprehensive three‐dimensional model L3‐S1 lumbar spine was developed validated. Based on model, three surgical groups were created: OLIF combined bilateral (BFJFF + OLIF), unilateral (UPSF (BPSF...
Background Although three-dimensional (3D) β-tricalcium phosphate (β-TCP) scaffolds serve as promising bone graft substitutes for the segmental defect treatment, no consensus has been achieved regarding their optimal 3D architecture. Methods In this study, we systematically compared four types of β-TCP with different architectures, including two porous scaffolds, one type tubular and solid efficacy in treating a rabbit model. Results Our study demonstrated that when to traditional promoted...
Objectives A subset of non-functioning pituitary macroadenomas (NFPAs) may exhibit early progression/recurrence (P/R) after surgical resection. The purpose this study was to apply radiomics in predicting P/R NFPAs. Methods Only patients who had undergone preoperative MRI and postoperative follow-ups for more than 1 year were included study. From September 2010 December 2017, 50 eligible diagnosed with pathologically confirmed NFPAs identified. Preoperative coronal T2WI contrast-enhanced (CE)...
Organ and tissue dysfunction represents a clinically significant condition. By integrating cell biology with materials science, engineering enables the reconstruction restoration of damaged tissues or organs, offering noninvasive repair approach. In our study, we replicated cellular growth environment by utilizing human umbilical cord-derived decellularized extracellular matrix (dECM) as modifying agent for polyethylene terephthalate (PET) polymeric fiber scaffold. This allowed us to create...
The influence of weak radio-frequency electromagnetic field (RF-EMF) on living organisms raises new concern because the Industrial, Scientific, and Medical (ISM) frequency band at 6.78 MHz being promoted by AirFuel Alliance for mid-range wireless power transfer (WPT) applications product development. Human exposure to RF-EMF radiation is unavoidable. In this study, we employed in vitro cell culture molecular biology approach coupled with integrated transcriptomic proteomic analyses uncover...
Abstract Osteoporotic bone defects are a major challenge in clinics for regeneration. With the condition of osteoporosis, excessive absorption and impaired osteogenesis result unexpectedly long healing procedures defects. In order to simultaneously enhance formation reduce resorption, polydopamine-coated porous titanium scaffold was designed, be integrated with anti-catabolic drug zoledronic acid nanoparticles (ZOL loaded gelatin NPs), which able achieve local sustained release ZOL as...
Background: At present, preoperative diagnosis of lateral cervical lymph node metastasis (LLNM) in patients with papillary thyroid carcinoma (PTC) mostly depends on the training and expertise ultrasound doctors. A machine-learning model for predicting LLNM accurately before PTC surgery may help to determine scope reduce unnecessary surgical trauma. Methods: The data primary who underwent thyroidectomy at Beijing Tongren Hospital between July 2009 June 2021 were retrospectively analyzed. All...
Enhancement of osteogenic capacity was achieved in a mineralized collagen composite, nano-hydroxyapatite/collagen (nHAC), by loading with synthetic peptides derived from BMP-2 residues 32-48 (P17-BMP-2). Rabbit marrow stromal cells (MSCs) were used vitro to study cell biocompatibility, attachment and differentiation on the composite counting kit, scanning electron microscopy (SEM) real-time reversed transcriptase-polymerase chain reaction analysis (RT-PCR). Optimal peptide dosage (1.0 µg/mL)...