- HIV/AIDS drug development and treatment
- Hepatitis C virus research
- HIV Research and Treatment
- HIV-related health complications and treatments
- Endometrial and Cervical Cancer Treatments
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Ovarian cancer diagnosis and treatment
- Mosquito-borne diseases and control
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
- Vector-borne infectious diseases
- Endometriosis Research and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- MRI in cancer diagnosis
- Leptospirosis research and findings
- Cytomegalovirus and herpesvirus research
- Autoimmune Bullous Skin Diseases
- Oral and gingival health research
Tzu Chi University
2018-2024
Tzu Chi Foundation
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2021
Buddhist Tzu Chi General Hospital
2018-2020
National Taiwan University Hospital
2019-2020
Several studies have demonstrated that significant weight gain occurs in some people living with HIV (PWH) after initiating integrase strand transfer inhibitors (INSTIs). Most on change been clinical trials primarily focused Africa, Europe, and North America, limited representation from real-world Asia. This retrospective observational study, conducted at nine designated HIV-care hospitals March 2019 to January 2024, aimed address this gap. Of the 533 patients screened, 314 met criteria for...
Abstract Background Higher rates of hepatitis C virus (HCV) reinfection after viral clearance have been well described among HIV‐positive men who sex with (MSM) in Europe. The epidemiology HCV reinfection, however, has rarely investigated patients Asia‐Pacific region. Methods We retrospectively identified recent infection had cleared their primary infection, either spontaneously or via treatment, between January 2011 and May 2018. All included were observed until 31 March 2019. was defined...
Understanding the risk behaviors associated with sexually-transmitted hepatitis C virus (HCV) infection among men who have sex (MSM) may inform public health policies and interventions aiming to achieve HCV microelimination.HIV-positive MSM had one of following conditions were enrolled undergo face-to-face questionnaire interviews collect information on their sexual practices in past 12 months: (1) elevation aminotransferases 6 months; (2) acquisition sexually transmitted infections (3)...
Increasing trends of HCV infection have been reported among HIV-positive men who sex with (MSM) in Europe, Australia and North America. The recently acquired MSM are less clear Asia-pacific region.All patients seeking care at a university hospital Taiwan tested for anti-HCV IgG least once annually to estimate the incidence seroconversion during 2011-2018. genotyping sequencing were performed multivariate logistic regression analysis was conducted identify factors associated MSM.During study...
Abstract Background Monitoring the trends of pre-treatment drug resistance (PDR) and resistance-associated mutations (RAMs) among antiretroviral-naïve people with HIV (PWH) is important for implementation treatment control programmes. We analysed HIV-1 PDR after introduction second-generation integrase strand-transfer inhibitors (INSTIs) in 2016 Taiwan, when single-tablet regimens non-nucleoside reverse-transcriptase inhibitor (NNRTI-) INSTI-based antiretroviral therapy became preferred...
ObjectivesWHO has recommended same-day antiretroviral therapy (SDART) initiation since 2017; however, higher attrition rates were noted in developing countries.MethodsWe included newly-diagnosed people with HIV (PWH) from 2018 to 2022 at 18 hospitals around Taiwan. SDART was defined as starting ART on the same day of diagnosis and rapid within 14 days diagnosis. A composite unfavorable outcome death after 30 diagnosis, loss follow-up (LTFU), or virologic failure rebound 12 months.ResultsAt...
Little is known about the engagement in hepatitis C virus (HCV) care and completion of HCV treatment people living with human immunodeficiency (HIV) (PLWH) who have coinfection Asia-Pacific region. Examining cascade can identify barriers to facilitate achievement micro-elimination PLWH.To investigate incident infections among PLWH Taiwan.PLWH infections, defined as seroconversion, were retrospectively identified by sequential anti-HCV testing all archived blood samples at National Taiwan...
Central nervous system symptoms occur in more than 80% of patients with scrub typhus infection; however, the entity central involvement is still not fully understood. We present case a patient fulminant multiple organ failure, including prolonged deep coma, and detail sequential neurological symptoms, signs, laboratory data, neuroradiological findings.
Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination impact cosmetic defect are important concerns. We report a Case cutaneous patient who ever traveled to Mexico before onset deteriorating wound around swollen left eyebrow. A diagnosis infection with Leishmania mexicana was made based on histopathological examination...
Objective: To investigate the diagnosis, treatment and prognosis of uterine serous carcinoma (USC), further analyze prognostic factors. Methods: USC patients who underwent surgery with complete follow-up at Cancer Hospital, Peking Union Medical College, Chinese Academy Sciences between January 1, 2004 December 31, 2014 were retrospectively reviewed. The Kaplan-Meier method Cox regression analysis used for survival analysis. Results: (1) Diagnosis treatment: study included 71 patients. Only...
Background: Same-day antiretroviral therapy (SDART) initiation is recommended for newly diagnosed people with HIV (PWH) by the WHO; however, higher attrition rates were noted after SDART in developing countries.Methods: To compare clinical outcomes versus rapid ART initiation, we included PWH from 2018 to 2022 Taiwan, where program of was implemented 2018. defined as starting on same day diagnosis and within 14 days diagnosis. A composite unfavorable outcome assessed, any deaths 30...
Objective: To analyze the prognosis and appropriate treatment modalities of patients with recurrence early stage (Ⅰb-Ⅱa) cervical squamous cancer primarily treated radical hysterectomy. Methods: This retrospective study included International Federation Gynecology Obstetrics (FIGO) Ⅰb Ⅱa recurrent who underwent hysterectomy from January 2007 to July 2015. Kaplan-Meier method Cox regression analysis were performed related prognostic factors overall survival progression-free survival, which...
Objective: To analyze the clinicopathological features and prognostic factors of patients with uterine clear cell carcinoma (UCCC). Methods: UCCC who underwent surgery complete follow-up at Cancer Hospital, Chinese Academy Medical Sciences Peking Union College between January 1, 2004 December 31, 2014 were retrospectively reviewed. The Kaplan-Meier method Cox regression analysis used for survival analysis. Results: study included 34 patients. Only 18 (52.9%) diagnosed preoperatively 8...