A5025428519- Electrical and Bioimpedance Tomography
- Body Composition Measurement Techniques
- Flow Measurement and Analysis
- Microfluidic and Bio-sensing Technologies
- Microwave Imaging and Scattering Analysis
- Hemodynamic Monitoring and Therapy
- Building Energy and Comfort Optimization
- Acute Ischemic Stroke Management
- Geophysical and Geoelectrical Methods
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Engineering Applied Research
- Autophagy in Disease and Therapy
- Cardiovascular Function and Risk Factors
- Non-Destructive Testing Techniques
- Photoacoustic and Ultrasonic Imaging
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Signaling Pathways in Disease
- Mosquito-borne diseases and control
- Protein Structure and Dynamics
- Virology and Viral Diseases
- Advanced Computational Techniques and Applications
- Brain Tumor Detection and Classification
- Ultrasound and Hyperthermia Applications
Air Force Medical University
2014-2025
Kunming Medical University
2014-2024
Yantaishan Hospital
2021
First Affiliated Hospital of Kunming Medical University
2014-2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Beijing Municipal Education Commission
2020
Fujian Medical University
2020
Union Hospital
2020
Weatherford College
2020
East China University of Science and Technology
2020
The rapid printing of 3D parts with desired electrical properties enables numerous applications. Fused deposition modeling (FDM) using conductive thermoplastic composites has been a valuable approach for such fabrication. produced by FDM possess various controllable structural features, but the effects features on remain to be determined. This study investigated these resistivity and anisotropy 3D-printed ABS/CB composites. process parameters FDM, including layer thickness, raster width, air...
CD147, a member of the immunoglobulin superfamily (IgSF), plays fundamental roles in intercellular interactions numerous pathological and physiological processes. Importantly, our previous studies have demonstrated that HAb18G/CD147 is novel hepatocellular carcinoma (HCC)-associated antigen, stimulates adjacent fibroblasts HCC cells to produce elevated levels several matrix metalloproteinases, facilitating invasion metastasis cells. In addition, has also been shown be universal cancer...
We present a Python-based, open source Electrical Impedance Tomography (EIT) library called pyEIT. It is multiplatform software released under the Apache License v2.0. pyEIT has clean architecture and well documented. implements state-of-the-art EIT imaging algorithms also capable of simple 2D/3D meshing. written in Python. accelerates analysis offline data can be incorporated into clinical applications. In this paper, we focus on illustrating fundamental design principles by using some...
Objective Variations of conductive fluid content in brain tissue (e.g. cerebral edema) change impedance and can potentially be measured by Electrical Impedance Tomography (EIT), an emerging medical imaging technique. The objective this work is to establish the feasibility using EIT as tool for monitoring content. Design a prospective study. Setting In study was used, first time, monitor variations clinical model with patients undergoing dehydration treatment. system developed house its...
Cerebral edema after brain injury can lead to damage and death if diagnosis treatment are delayed. This study investigates the feasibility of employing electrical impedance tomography (EIT) as a non-invasive imaging tool for monitoring development cerebral edema, in which related water content is compared with intracranial pressure (ICP). We enrolled forty patients hemorrhage who underwent lateral external ventricular drain intraventricular ICP EIT 3 h initiation dehydration treatment. The...
Introduction Electrical impedance tomography (EIT) enables non-invasive, continuous, bedside evaluation of ventilation/perfusion (V/Q) match. To avoid the presence invasive monitoring for cardiac output in relative V/Q ratio calculation, we proposed a novel calibration method based on arterial blood pressure to optimize EIT match assessments. Methods We involved 12 mechanically ventilated piglets three experimental phases: baseline, pulmonary embolism, and atelectasis. After thorough...
Phantom experiments are an important step for testing during the development of new hardware or imaging algorithms head electrical impedance tomography (EIT) studies. However, due to sophisticated anatomical geometry and complex resistivity distribution human head, constructing accurate phantom EIT research remains challenging, especially skull modelling. In this paper, we designed fabricated a novel with anatomically realistic continuously varying based on 3D printing techniques. The model...
Intracranial bleeding is one of the most severe medical emergencies in neurosurgery. Early detection or diagnosis would largely reduce rate disability and mortality, improve prognosis patients. Electrical Impedance Tomography (EIT) can non-invasively image internal resistivity distribution within a human body using ring external electrodes, thus promising technique to promptly detect occurrence intracranial bleedings because blood differs from other brain tissues resistivity. However, so far...
To evaluate the efficacy of tirofiban administered at different time points within 24 hours intravenous thrombolysis with alteplase in acute ischemic stroke.Patients who underwent and fulfilled other inclusion criteria were randomly divided into 4 groups according to administration: Group A (2 h), B (2-12 C (12-24 D (control). The changes National Institutes Health Stroke Scale score, modified Rankin adverse events analyzed.At 7 ± 1 day, was better than that (P = .006) .001), but there no...
Electrical impedance tomography (EIT) is a bedside tool for lung ventilation and perfusion assessment. However, the ability long-term monitoring diminished due to interferences from clinical interventions motion artifacts. The purpose of this study investigate feasibility discrete wavelet transform (DWT) detect remove common types artifacts in thoracic EIT.Baseline drifting, step-like spike-like were simulated mimic three decomposition was employed characterize those different frequency...
The hepatocellular carcinoma-associated antigen HAb18G/CD147, a member of CD147 family, could promote tumour invasion and metastasis via inducing the secretion matrix metalloproteinases (MMP). Anti-CD147 monoclonal antibodies (MoAb) have exhibited obvious inhibitory effect on MMP induction. However, none epitopes these MoAb has been reported. We previously prepared five against named HAb18, 3B3, 1B3, 5A5 4D2. To map MoAb, series truncated fragments extracellular region HAb18G/CD147 was...
Electrical impedance tomography (EIT) is a noninvasive, radiation-free, and low-cost imaging modality for monitoring the conductivity distribution inside patient. Nowadays, time-difference EIT (tdEIT) used extensively as it has fast speed can reflect dynamic changes of diseases, which make attractive number medical applications. Moreover, modeling errors are compensated to some extent by subtraction voltage measurements collected before after change. However, tissue varies with frequency...
Abstract Objective : This study investigated the feasibility of electrical impedance tomography (EIT) for monitoring deterioration ischemic lesion after onset stroke. Approach Fifteen rats were randomly distributed into two groups: operated to establish a right middle cerebral artery occlusion (MCAO) ( n = 10), and sham-operated 5). Then, kept 2 h under anesthesia EIT monitoring. Subsequently, descriptive statistical analysis was performed on whole-brain resistivity changes,...
Objective To investigate the possible use of electrical impedance tomography (EIT) in monitoring focal cerebral infarction a rabbit model. Methods A model was established eight New Zealand rabbits using photochemical method without craniectomy. Focal confirmed by histopathological examination. Intracranial variation measured 16 electrodes placed circle on scalp. EIT images were obtained damped least-squares reconstruction algorithm. The average resistivity value (ARV) infarct region...
Electrical impedance tomography (EIT) is low-cost and noninvasive has the potential for real-time imaging bedside monitoring of brain injury. However, injury by EIT suffers from image noise (IN) resolution problems, causing blurred reconstructions. To address these a least absolute shrinkage selection operator model built, fast iterative shrinkage-thresholding algorithm with continuation (FISTA-C) proposed. Results numerical simulations head phantom experiments indicate that FISTA-C reduces...
[131 I]Metuximab injection (Licartin) was an efficient therapeutic anti-hepatocellularcarcinoma (HCC) radioimmunological agent generated by labeling 131 I with the murinemonoclonal antibody fragment HAb18-F(ab’)2 but human anti-mouse (HAMA)response in some patients after administration limited its clinical use. To reduce theimmunogenicity of murine antibody, we attempted to humanize HAb18 variable domainresurfacing based on three-dimensional structure Fv fragment. Considering thesurface...
The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 A549 cells. However, the effect both glycoproteins on mitochondria remains elusive. Here, we found that cooperation increases mitochondrial biogenesis but does not cause damage. We observed change morphological characteristics spatial distribution intracellular mitochondria. cooperate cooperatively to ER stress UPRmt. Our preliminary data suggested disturb fusion-fission homeostasis enhance...