A5101705393- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Antioxidant Activity and Oxidative Stress
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Retinoids in leukemia and cellular processes
- Corneal surgery and disorders
- Chronic Kidney Disease and Diabetes
- Advanced Glycation End Products research
- Nosocomial Infections in ICU
- Cardiovascular Disease and Adiposity
- Genetic Associations and Epidemiology
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Intraocular Surgery and Lenses
- Pneumonia and Respiratory Infections
- Adipokines, Inflammation, and Metabolic Diseases
- Ocular Oncology and Treatments
- Adrenal Hormones and Disorders
- Remote Sensing in Agriculture
- Ophthalmology and Visual Health Research
- Humic Substances and Bio-Organic Studies
- Global Health Care Issues
- Streptococcal Infections and Treatments
Khoo Teck Puat Hospital
2012-2024
Singapore Eye Research Institute
2012-2024
Central University of Himachal Pradesh
2024
National Institute of Ayurveda
2024
Singapore National Eye Center
2015-2020
National University of Singapore
2014-2019
Duke-NUS Medical School
2014-2019
National University Health System
2019
University Health System
2019
Korea National Institute of Health
2017
Abstract Importance Asian Indians are the fastest growing migration groups in world. Studies evaluating impact of on disease outcomes this population rare. Background We describe methodology Singapore Indian Eye Study‐2 (SINDI‐2) aimed to evaluate status diabetic retinopathy and other major age‐related eye diseases living an urban environment. Design Population‐based cohort study. Participants A total 2200 adults had participated baseline SINDI (2007–2009, mean age [range] = 57.8 [42.7–84.1]...
There are several techniques for measuring macular pigment (MP) in vivo, of which Raman spectroscopy (RS) is a recently developed objectiveThis study reports the reproducibility, test-retest variability, and validity RS MP readings, by comparing them with heterochromatic flicker photometry (HFP).MP was measured HFP 120 healthy subjects, latter technique also used on two separate occasions sample 20 subjects to investigate intersessional variability readings. Intrasessional reproducibility...
Age-related maculopathy (ARM) is the leading cause of blindness in elderly. Although beneficial therapeutic strategies have recently begun to emerge, much remains unclear regarding etiopathogenesis this disorder. Epidemiologic studies enhanced our understanding ARM, but data, often conflicting, has led difficulties with drawing firm conclusions respect risk for condition. As a consequence, we saw need assimilate published findings factors through review literature appraising results from...
Diabetic retinopathy (DR) is a leading cause of vision-loss globally among type 2 diabetes (T2DM) patients. Information on the economic burden DR in Singapore limited. We aim to identify total annual direct medical costs at different stages, and examine factors influencing costs. Four hundreds seventy T2DM patients who attended Diabetes Centre secondary hospital 2011–2014 were included. Digital color fundus photographs assessed for masked fashion. Retinopathy severity was further categorized...
Purpose/Aim: Diabetic retinopathy (DR) is the most common diabetic microvascular complication, and it typically develops after 10 years of diabetes diagnosis. The primary aim this study was to evaluate association between adiposity DR susceptibility among individuals with longstanding type 2 mellitus (T2D). Materials Methods: In cross-sectional study, assessed by fundus photography in 953 T2D subjects. prevalence categories duration evaluated. a sub-cohort analysis, subjects having for ≥10...
Background/aims In order to address the eye care needs of increasing numbers elderly Chinese globally, there is a need for comprehensive understanding on longitudinal trends age-related diseases among Chinese. We herein report key findings from baseline Singapore Eye Study (SCES-1), and describe rationale methodology 6-year follow-up study (SCES-2). Methods 3353 adults who participated in SCES-1 (2009–2011) were invited SCES-2 (2015–2017). Examination procedures included standardised ocular,...
Purpose: This study was undertaken to assess serial month-to-month consistency of macular pigment (MP) optical density and serum concentrations lutein (L) zeaxanthin (Z). Four healthy subjects aged between 23 51 years volunteered participate in this study. Methods: MP (measured psychophysically using heterochromatic flicker photometry [HFP]), L Z (quantified high-performance liquid chromatography [HPLC]), were recorded every month for 24 consecutive months. Results: Mean (±SD) 0.361 (0.086)...
Aims Diabetes is a major public health problem in migrants and ethnic minorities worldwide. We determined the incidence risk factors of diabetic retinopathy (DR) migrant Indians living Singapore. Methods included data from 759 Indian adults with diabetes, who participated baseline (aged 40–80 years, 2007–2009) 6-year follow-up 2012–2015 Singapore Eye Study. Retinal photographs were graded for presence severity DR using modified Airlie House Classification. Incidence was assessed participants...
Fluctuation of kidney function may signify intra-glomerular microvascular hemodynamic instability. We aim to examine the association long-term serum creatinine and estimated glomerular filtration rate variability with diabetic retinopathy.We included type 2 diabetes mellitus patients who attended Diabetes Centre in 2011-2014 were followed up (median = 3.2 years). Digital colour fundus photographs assessed for retinopathy at follow-up. Diabetic severity was categorized into non-proliferative...