A5101728614- Collagen: Extraction and Characterization
- Microbial Natural Products and Biosynthesis
- biodegradable polymer synthesis and properties
- Meat and Animal Product Quality
- Plant biochemistry and biosynthesis
- Bone Tissue Engineering Materials
- Enzyme Catalysis and Immobilization
- Genomics and Phylogenetic Studies
- Dyeing and Modifying Textile Fibers
- Protein Hydrolysis and Bioactive Peptides
- Adsorption and biosorption for pollutant removal
- Advanced Computational Techniques and Applications
- Electrospun Nanofibers in Biomedical Applications
- Microbial Metabolic Engineering and Bioproduction
- 3D Shape Modeling and Analysis
- Surface Modification and Superhydrophobicity
- Material Properties and Processing
- Geomechanics and Mining Engineering
- Phytochemistry and Biological Activities
- Enzyme Structure and Function
- Rock Mechanics and Modeling
- Cultural Heritage Materials Analysis
- Hydrogels: synthesis, properties, applications
- Advanced Decision-Making Techniques
- Proteins in Food Systems
Shaanxi University of Science and Technology
2019-2024
Chinese Academy of Sciences
2006-2024
Wuhan Institute of Virology
2024
Shanghai Institute of Organic Chemistry
2006-2023
Virginia Tech
2023
University of Chinese Academy of Sciences
2019-2023
Xi’an University
2021-2023
China Institute of Water Resources and Hydropower Research
2014-2021
Mississippi State University
2021
Sichuan University
2013-2020
A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded biosynthetic gene clusters. Information about these clusters, is currently dispersed throughout the literature, making it difficult exploit. To facilitate consistent systematic deposition retrieval data on we propose Minimum a Biosynthetic Gene cluster (MIBiG) standard.
Tetrahydroisoquinolines (THIQs) with a C1-aryl-substituted groups are common in many natural and synthetic compounds of biological importance. Currently, their enantioselective synthesis primarily reliant on chemical catalysis. Enzymatic using imine reductase is very attractive, because the cost-effectiveness, high catalytic efficiency, enantioselectivity. However, steric hindrance 1-aryl substituents make this conversion challenging, current successful examples mostly restricted to simple...
Abstract Coupling distinct enzymatic effectors emerges as an efficient strategy for defense against phage infection in bacterial immune responses, such the widely studied nuclease and cyclase activities type III CRISPR-Cas system. However, concerted other systems are poorly understood. Here, we biochemically structurally characterize a two-component system DUF4297–HerA, demonstrating that DUF4297–HerA confers resistance by cooperatively cleaving dsDNA hydrolyzing ATP. DUF4297 alone forms...
The physicochemical properties of collagen solutions (5 mg/ml) cross-linked by various amounts glutaraldehyde (GTA) [GTA/collagen (w/w) = 0–0.5] under acidic condition (pH 4.00) were examined. Based on the results determination residual amino group content, sodium dodecyl sulphate–polyacrylamide gel electrophoresis, dynamic rheological measurements, differential scanning calorimetry and atomic force microscopy (AFM), it was proved that possessed strikingly different depending amount GTA. At...
Chlorothricin, isolated from Streptomyces antibioticus, is a parent member of spirotetronate family antibiotics that have long been appreciated for their remarkable biological activities. ChlF1 plays bifunctional roles in chlorothricin biosynthesis by binding to its target genes (chlJ, chlF1, chlG, and chlK). The dissociation constants these are ∼ 102-140 nm. A consensus sequence, 5'-GTAANNATTTAC-3', was found sites. represses the transcription chlK but activates chlJ, which encodes key...
Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser with a combination two near-infrared lasers (980 1064 nm), was performed first time in this study. One centimeter long, full-thickness were made on Wistar rat's dorsal skin. The efficiencies laser-welding different parameters investigated. Incision-healing, histology examination, tensile strength test recorded. irradiance level 15.9 W/cm2 both 980...