- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Leprosy Research and Treatment
- Ship Hydrodynamics and Maneuverability
- Parasitic Infections and Diagnostics
- Viral gastroenteritis research and epidemiology
- Maritime Navigation and Safety
- Maritime Transport Emissions and Efficiency
- Cancer therapeutics and mechanisms
- Viral Infections and Vectors
- Orthopedic Surgery and Rehabilitation
- Ocular Diseases and Behçet’s Syndrome
- Animal Virus Infections Studies
- Fluid Dynamics and Mixing
- Parasitic infections in humans and animals
- Advanced Multi-Objective Optimization Algorithms
- Hydrology and Drought Analysis
- Salmonella and Campylobacter epidemiology
- HIV/AIDS Research and Interventions
- Leptospirosis research and findings
- Cystic Fibrosis Research Advances
- Advanced Measurement and Detection Methods
- Elbow and Forearm Trauma Treatment
- Combustion and flame dynamics
Shanghai Maritime University
2016-2024
University of Virginia
2014-2024
Guizhou Center for Disease Control and Prevention
2024
Vertex Pharmaceuticals (United States)
2023
Sixth Affiliated Hospital of Kunming Medical University
2022
Kunming Medical University
2022
Xi'an Chest Hospital
2020
Center for Tuberculosis Control of Guangdong Province
2020
Guizhou Normal University
2019-2020
Anhui Provincial Hospital
2020
ABSTRACT Campylobacter is a common bacterial enteropathogen that can be detected in stool by culture, enzyme immunoassay (EIA), or PCR. We compared culture for C. jejuni/C. coli , EIA (ProSpecT), and duplex PCR to distinguish non- jejuni/coli on 432 diarrheal matched control samples from infants multisite longitudinal study of enteric infections Tanzania, Bangladesh, Peru. The sensitivity specificity were 8.5% 97.6%, respectively, with the results 8.7% 98.0%, . Most (71.6%) EIA-positive...
Background: Data from many large cities in China show HIV prevalence among men who have sex with (MSM) increasing dramatically over the recent years, making transmission MSM a growing concern. To facilitate targeted prevention Chongqing, surveys were conducted to examine and its associated factors 2006 2007. Methods: Surveys 2007 3 districts of Chongqing at venues cruising areas where frequent. Univariate bivariate analysis on demographic, behavioral, biological data. Results: was 19.7%...
No data are available on the etiology of diarrhea requiring hospitalization after rotavirus vaccine introduction in Africa. The monovalent was introduced Tanzania 1 January 2013. We performed a impact and effectiveness study as well quantitative polymerase chain reaction (qPCR)–based at rural Tanzanian hospital. obtained admissions among children <5 years to Haydom Lutheran Hospital between 2010 31 December 2015 estimated all-cause admissions. then using test-negative design. Finally, we...
The present study analyzed the impact of COVID-19 pandemic on prevalence and incidence new leprosy cases, as well diversity, distribution, temporal transmission Mycobacterium leprae strains at county level in leprae-endemic provinces Southwest China. A total 219 cases during two periods, 2018-2019 2020-2021, were compared. We genetically characterized 83 clinical isolates M. Guizhou using variable number tandem repeats (VNTRs) single nucleotide polymorphisms (SNPs). obtained genetic profiles...
Abstract More than 100 counties, mainly in southwest China, report incidence rates of leprosy >1/100,000. The current study analysed the epidemiology China to improve our understanding transmission pattern and control programs. 207 counties were selected China. Leprosy patients their household contacts recruited. data from medical interview serological antileprosy antibody analysed. A total 2,353 new cases interviewed. distribution was partly associated with local natural economic...
Prolonged postoperative ileus (PPOI) is one of the common complications in gastric cancer patients who underwent gastrectomy. Evidence on predictors PPOI after gastrectomy limited and few prediction models nomogram are used to estimate risk PPOI. We hypothesized that a predictive can be for clinical estimation patients.To investigate factors establish estimation.Between June 2016 March 2017, data 162 with were obtained from prospective observational registry database. Clinical fulfilled...
Reports on antimicrobial resistance (AMR) of Mycobacterium leprae, relationship with bacteriological index (BI), and transmission in China are limited. We investigated the emergence AMR mutations, between BI complete, moderate lack decline cases, molecular epidemiological features cases by enrolling 290 leprosy from four endemic provinces. Seven (2.41%), one (0.34%), five (1.72%), (0.34%) strains had single mutations folP1, rpoC, gyrA, gyrB, 23S rRNA, respectively. Double folP1 rpoB gyrA...
Background Investigations of Mycobacterium tuberculosis genetic diversity in China have indicated a significant regional distribution. The aim this study was to characterize the genotypes clinical M. isolates obtained from Gansu, which has special geographic location China. Methodology/Principal Findings A total 467 strains isolated Gansu Province were genotyped by 15-locus mycobacterial interspersed repetitive units–variable number tandem repeats (MIRU-VNTR) and spoligotyping. results...
Understanding the nature of Mycobacterium leprae transmission is vital to implement better control strategies for leprosy elimination. The present study expands knowledge county-level strain diversity, distribution, and patterns in endemic provinces China.We genetically characterized 290 clinical isolates M. from four using variable number tandem repeats (VNTR) single nucleotide polymorphisms (SNPs). Attained genetic profiles cluster consequences were contrasted with geographical migration...
Pulmonary tuberculosis (TB) is a severe infectious respiratory disease, the burden of which remains high in China. To provide scientific evidence for developing more targeted prevention and control strategies, this study aimed to determine incidence trends explore epidemiological characteristics pulmonary TB Anhui Province, Eastern China between 2013 2018.The retrospective analyzed information regarding cases reported by National Infectious Disease Reporting System census data collected from...
The diesel spray characteristics are strongly influenced by the flow dynamics inside injector nozzle. Moreover, off-axis oscillation of needle could lead to variation orifice in In this paper, was investigated using high-speed X-ray phase contrast imaging and quantitative image processing. effects fuel, injection pressure nozzle geometry on were analyzed. results showed that vertical horizontal independent pressure. maximum range 14μ m found. Biodiesel application slightly decreased due high...
Abstract In order to shorten the optimization cycle of ship design and solve time‐consuming problem computational fluid dynamics (CFD) numerical calculation, this paper proposes a multi‐precision back‐propagation neural network (MP‐BP) approximation technology. Fewer high‐precision samples more low‐precision were used construct an approximate model, (BP) was train samples. So that model is as close possible real achieving effect model. Subsequently, verification typical hull form are given....
ABSTRACT Ship form optimization poses a complex and high‐dimensional engineering challenge. Therefore, when conducting multi‐objective research of ship forms, traditional intelligent algorithms are prone to falling into local optima solution difficult converge. In order effectively improve the diversity convergence performance algorithm, this paper improves bare‐bones particle swarm (BBMOPSO) algorithm by dynamically adjusting global search step sizes, verifies algorithm's reliability...
Multidrug-resistant tuberculosis (MDR-TB) is currently a major problem in China. The prevention and treatment work for MDR-TB patients started late Anhui province. To determine the prevalence of sputum smear-positive TB (SSPTBPs) analyze risk factors province, we conducted an investigation drug resistance among SSPTB outpatients from September 2015 to August 2016.
To compare the clinical efficacy of micro steel plate and Kirschner needle oblique transverse internal fixation adjacent metacarpal bone in treatment diaphyseal fracture.Fifty-nine patients with fractures admitted between January 2018 September 2021 were selected as study subjects divided into observation group (29 cases) control (30 based on different methods. The was treated wire bones, while fixation. Postoperative complications, operation time, incision length, fracture healing cost,...
Although fluoroquinolones (FQs) are the backbone drugs for treatment of multidrug-resistant tuberculosis (MDR-TB), knowledge about resistance pattern and molecular characterization new-generation FQs in Chongqing is limited. This study aimed to investigate rate mutation types later-generation against MDR-TB Chongqing, further explore relationship between different genotypes phenotypes. A total 967 clinical strains were characterized using multilocus sequence typing drug susceptibility...
Abstract Multi‐objective optimization of ship form can effectively reduce energy consumption, and is one the important research topics green ships. However, computational cost numerical simulation based on fluid dynamics (CFD) theory relatively high, which affects efficiency optimization. Traditional subjective weighting methods mostly rely expert's experience, scientificity This paper integrates CFD method, improved multi‐objective algorithm objective method to build a framework. Conduct...
Abstract Background Enteric infections are hypothesized to be associated with intussusception in children. A small increase following rotavirus vaccination has been seen some settings. We conducted post-marketing surveillance for vaccine, Rotavac introduction India and evaluated association of enteric pathogens. Methods In a case-control study nested within large sentinel hospital-based program India, stool samples from 272 children aged less than 2 years admitted age-, gender-...
Abstract In a typical gas lift system, slippage between gaseous and liquid phases results in increased water cut decreased reservoir pressure which reduces lifting efficiency causes low oil recovery. Pig is novel artificial technique proposed recent years for effectively reducing accumulation increasing two-phase flow stability certain special cases, such as high gas-liquid ratio, pressure, horizontal and/or rather deep wells, highly viscous or waxy oil, sand production, etc. this paper,...
Objective To evaluate the resistance of multidrug-resistant Mycobacterium tuberculosis (M.tb) strains to bedaquiline (BDQ) and analyze relationships between their genotypes BDQ-resistant phenotypes in order provide a scientific basis for rational use BDQ treatment (MDR-TB) clinical practice. Methods A total 387 M. tb strains, including 100 pan-susceptible 287 isolated from patients with MDR (MDR-TB strains), were enrolled this study. Of MDR-TB 77 collected Chongqing 2015 other...