A5078731988- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Health Literacy and Information Accessibility
- Social Media in Health Education
- Circular RNAs in diseases
- RNA modifications and cancer
- Cancer-related gene regulation
- Antifungal resistance and susceptibility
- MicroRNA in disease regulation
- Analytical Chemistry and Chromatography
- Misinformation and Its Impacts
- Receptor Mechanisms and Signaling
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects and Assays
- FOXO transcription factor regulation
- Head and Neck Cancer Studies
- Sperm and Testicular Function
- Extracellular vesicles in disease
- Analytical chemistry methods development
- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Phytochemical Studies and Bioactivities
- Paraoxonase enzyme and polymorphisms
Peking University
2024-2025
Peking University Cancer Hospital
2024-2025
Nanjing University
2016-2024
Nanjing General Hospital of Nanjing Military Command
2015-2024
Yunnan University
2023-2024
Nanjing Medical University
2020-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Sun Yat-sen University
2024
Beijing Jiaotong University
2024
Anhui University of Traditional Chinese Medicine
2024
Abstract The ideal vertical phase separation active layer morphology is crucial for the photoelectric conversion of organic solar cells. In this work, a layer‐by‐layer sequential deposition method used to prepare D18/L8‐BO‐based cells and dual additives strategy adopted construct layer. Additive DIM regulates crystallization D18 layer, additive DIO induces L8‐BO diffuse into interior form composition distribution with large donor/acceptor interpenetrated regions. improvement induced by...
// Yuan Qin 1, 2, * , Qiang Zhang Shan Lee Wei-long Zhong Yan-rong Liu 2 Hui-juan Dong Zhao Shuang Chen Ting Xiao Jing Meng Xue-shuang Wang Bo Sun Ting-ting Dai Cheng Yang Tao Hong-gang Zhou 1 State Key Laboratory of Medicinal Chemical Biology and College Pharmacy, Nankai University, Tianjin, China Tianjin Molecular Drug Research, International Joint Academy Biomedicine, These authors have contributed equally to this work Correspondence to: Sun, e-mail: sunrockmia@hotmail.com Zhou,...
// Tao Xie 1, * , Jian Geng Ye Wang 1 Liya 2 Mengxi Huang Jing Chen Kai Zhang Lijun Xue Xiaobei Liu Mao Yanan Qian Tingting Dai Lili Ren Hongju Yu Rui Longbang Cheng Xiaoyuan Chu Department of Medical Oncology, Jinling Hospital, Nanjing Clinical School Southern University, 210002, China Medicine, These authors have contributed equally to this work Correspondence to: Chu, email: chuxiaoyuan000@163.com Chen, chencheng1289@126.com Keywords: colorectal cancer, FOXM1, 5-FU, chemoresistance...
The presence of sulfonamide (SA) residues in foods is largely due to the raising animals with antibiotics added or polluted feedstuff. In this paper, a sensitive method was developed for determination three sulfonamides animal-derived food; SAs include sulfadimidine (SDD), sulfadiazine (SDZ), and sulfathiazole (STZ). based on capillary zone electrophoresis (CE) online chemiluminescence (CL) detection, using an Ag(III) complex as oxidant. These have inhibiting effect Ag(III)-luminol CL...
Immune checkpoint inhibitors (ICIs) benefit only a subset of patients in advanced esophageal squamous cell carcinoma (ESCC). Our study aims to develop and validate clinically accessible model better identify those who may respond ICIs. This enrolled ESCC treated with ICIs at Peking University Cancer Hospital from January 14, 2016, 26, 2024 for the training cohort Harbin Medical between 10, 2019, July 6, 2022 validation cohort. Combined positive score (CPS) was recorded assess predictive...
Halide perovskites have garnered significant attention for their exceptional carrier mobility, balanced bipolar transport properties, and ion-electron mixing conductivity, making them highly promising applications, such as solar cells, photodetectors, memristors. Despite potential, intrinsic ions defects within these materials complicate effective doping, interactions between metal electrodes perovskite can trigger interfacial chemical reactions that compromise device stability performance....
β-elemene has been observed to exert inhibitory effects on a multitude of tumors, primarily through multiple pathways such as the inhibition cancer cell proliferation and induction apoptosis. The present study is designed elucidate role underlying mechanisms in therapeutic intervention non-small lung (NSCLC). Both vitro vivo experimental models corroborate potency NSCLCs. Our findings indicate that facilitates maturation miR-127-3p by inhibiting CBX8. Functioning an upstream regulator MAPK4,...
Dysregulated alternative splicing (AS) plays critical roles in driving cancer progression, and the underlying mechanisms remain largely unknown. Here, we demonstrated that PHF5A, a component of U2 small nuclear ribonucleoproteins, was frequently upregulated colorectal (CRC) samples associated with poor prognosis. PHF5A promoted proliferation metastasis CRC cells vitro vivo. Transcriptomic analysis identified PHF5A-regulated AS targets pathways. Particularly, induced TEAD2 exon 2 inclusion to...
Transcription factor forkhead box M1 (FOXM1) is a crucial regulator in colorectal cancer (CRC) progression. However, the regulatory mechanisms causing dysregulation of FOXM1 CRC remain unclear. Dual-luciferase reporter assay was conducted to determine as miR-6868-5p target. The function and angiogenesis verified vitro. Intratumoral injection model constructed explore effect on vivo. Chromatin immunoprecipitation assays were used assess direct binding H3K27me3 miR-6868 promoter. Through...
5-Fluorouracil is a commonly used chemotherapy drug for colorectal cancer. Resistance to remains challenge. This research aimed explore the mechanism of resistance in RT-qPCR and Western blot were determine RNA protein expression both cells exosome. Assays vitro vivo performed measure role miR-149-5p cancer cells. RIP, luciferase activity report, pulldown assay applied detect association PTOV1-AS1, SUV39H1, miR-149-5p, FOXM1. MiR-149-5p was down-expressed 5-Fluorouracil-resistant enhanced...
WeChat (Tencent) is one of the most important information sources for Chinese people. Relevantly, various health-related data are constantly transmitted among users. public accounts (WPAs) health rapidly emerging. Health-related have a significant impact on health. Because rise in web-based health-seeking behavior, general has grown accustomed to obtaining cancer from WPAs. Although WPAs make it easy people obtain information, quality questionable.
Background Seeking health information on the internet is a popular trend. Xigua Video, short video platform in China, ranks among most accessed websites country and hosts an increasing number of videos with medical information. However, nature these frequently unscientific, misleading, or even harmful. Objective Little known about Video as source breast cancer. Thus, study aimed to investigate contents, quality, reliability cancer–related content Video. Methods On February 4, 2020, search...
Most of gastric carcinoma (GC) is attributed to infection by Helicobacter pylori (H. pylori) but there increasing evidence that the positive H. status correlates with better prognosis in GC. The pylori-induced cellular immune response may suppress cancer and this work, recombinant pcDNA3 plasmids encoding various fragments virulence genes cagA, vacA babA are constructed combined into groups immunize BALB/c mice. activated splenic CD3+ T cells purified anticancer effects investigated vitro...
AIM: To investigate the difference in risk factors between non-arteritic anterior ischaemic optic neuropathy (NAION) and central retinal artery occlusion (CRAO) develop a predictive diagnostic nomogram. METHODS: The study included 37 patients with monocular NAION, 20 CRAO, 24 hypertension. Gender, age, systemic diseases were recorded. Blood routine, lipids, hemorheology, carotid brachial doppler ultrasound, echocardiography collected. disc area, cup cup-to-disc ratio (C/D) of unaffected eye...
Non-small cell lung cancer (NSCLC) is one of the main causes cancer-related death worldwide, with a serious impact on human health and life. The identification NSCLC at an early stage formidable task that frequently culminates in belated diagnosis. LncRNA kind noncoding RNA limited protein-coding capacity, its expression out balance many cancers, especially NSCLC. A large number studies have reported lncRNA acts vital role regulating angiogenesis, invasion, metastasis, proliferation...