A5054552540- Salmonella and Campylobacter epidemiology
- Trace Elements in Health
- Animal Virus Infections Studies
- Listeria monocytogenes in Food Safety
- Brucella: diagnosis, epidemiology, treatment
- Viral gastroenteritis research and epidemiology
- Antimicrobial Peptides and Activities
- Antibiotic Resistance in Bacteria
- Galectins and Cancer Biology
- Animal Nutrition and Physiology
- Drug Transport and Resistance Mechanisms
- Escherichia coli research studies
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Burkholderia infections and melioidosis
- Tuberculosis Research and Epidemiology
- Immune Response and Inflammation
- Animal Disease Management and Epidemiology
- Veterinary medicine and infectious diseases
- Biochemical and Structural Characterization
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture disease management and microbiota
- Mycobacterium research and diagnosis
- Animal Diversity and Health Studies
- S100 Proteins and Annexins
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2022-2025
Istituto Superiore di Sanità
2009-2019
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche
2016-2019
National Institute for Public Health and the Environment
2019
Universidad Complutense de Madrid
2014-2016
University of California, Irvine
2012
Salmonella enterica serovar Typhimurium is an important zoonotic gastrointestinal pathogen responsible for foodborne disease worldwide. It a successful enteric because it has developed virulence strategies allowing to survive in highly inflamed intestinal environment exploiting inflammation overcome colonization resistance provided by microbiota. In this study, we used piglets featuring intact microbiota, which naturally develop gastroenteritis, as model salmonellosis. We compared the...
Zinc is an essential metal for cellular homeostasis and function in both eukaryotes prokaryotes. To acquire this nutrient, bacteria employ transporters characterized by different affinity the metal. Several studies have investigated role of high transporter ZnuABC bacterial response to zinc shortage, showing that has a key adapting starvation. In contrast, low importer ZupT been subject limited investigations. Here we show Salmonella strain lacking impaired its ability grow devoid...
Foot and Mouth disease (FMD) transmission is strongly related to the distribution density of FMD-susceptible animals. In this study, we applied a model simulate spread FMD in three Italian regions with different livestock demographics (densely, medium, sparsely populated) order assess cost effectiveness control options within framework contingency plan. The results simulations showed that stamping-out was sufficient outbreak medium populated areas whereas, densely areas, only vaccinations...
Salmonellosis in water buffalo (Bubalus bubalis) calves is a widespread disease characterized by severe gastrointestinal lesions, profuse diarrhea and dehydration, occasionally exhibiting systemic course. Several Salmonella serovars seem to be able infect buffalo, but isolates collected from this animal species have been poorly characterized. In the present study, prevalence of spp. affected lethal gastroenteritis was assessed, polyphasic characterization isolated strains S. Typhimurium...
Trained immunity is the capacity of innate immune cells to produce an improved response against a secondary infection after previous unrelated infection. Salmonellosis represents public health issue and affects pig farming industry. In general, vaccination salmonellosis still facing problems regarding control distinct serovars. Therefore, we hypothesized that immunostimulant based on heat inactivated Mycobacterium bovis (HIMB) could have training effect in pigs challenged with Salmonella...
Salmonella Typhimurium (S. Typhimurium) is responsible for foodborne zoonotic infections that, in humans, induce self-limiting gastroenteritis. The aim of this study was to evaluate whether the wild-type strain S. (STM14028) able exploit inflammation fostering an active infection. Due similarity between human and porcine diseases induced by Typhimurium, we used piglets as a model salmonellosis gastrointestinal research. This showed that STM14028 efficiently colonize vitro mono-macrophages...
Surveillance data collected in the period 2017-20 for Brucella spp. wildlife of Lombardy Region northern Italy were used to describe exposure species wild boar (Sus scrofa), European brown hare (Lepus europaeus), fallow deer (Dama dama), red (Cervus elaphus), and roe (Capreolus capreolus). Among tested species, (n=6,440) showed highest percentage seropositive samples (5.9%). Notably, boars perifluvial area Po River higher percentages positivity than those pre-Alpine district. In addition,...
Poultry is the most likely source of livestock-associated Extended Spectrum Beta-Lactamase (ESBL) and plasmid-mediated AmpC (pAmpC)-producing E. coli (EC) for humans. We tested hypothesis that farming methods have an impact on load ESBL/pAmpC-EC in gut broilers at slaughter. Isolates (n = 156) antibiotic-free (AF), organic (O), conventional (C) animals were characterized antibiotic susceptibility resistance genes. Thirteen isolates whole-genome sequenced. The average loads cecal contents...
Salmonella enterica serovar Choleraesuis (S. Choleraesuis) infection causes a systemic disease in pigs. Vaccination could represent solution to reduce prevalence farms. In this study, we aimed assess the efficacy of an attenuated strain Typhimurium ΔznuABC) against S. infection. The vaccination protocol combined priming with ΔznuABC vaccine and boost inactivated compared protection conferred that induced by vaccine. first group piglets was orally vaccinated boosted Choleraesuis, second one...